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Accession:CHEBI:43797 term browser browse the term
Definition:A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens has been replaced by an ethynyl group. It causes the irreversible inactivation of gamma-cystathionase (also known as cystathionine gamma-lyase) and is used as an affinity labeling reagent for gamma-cystathionase and other enzymes.
Synonyms:exact_synonym: (2S)-2-aminopent-4-ynoic acid
 related_synonym: (S)-2-amino-4-pentynoic acid;   (S)-2-propargylglycine;   (S)-alpha-propargylglycine;   (S)-propargylglycine;   Formula=C5H7NO2;   InChI=1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)/t4-/m0/s1;   InChIKey=DGYHPLMPMRKMPD-BYPYZUCNSA-N;   L-2-propynylglycine;   L-C-propargylglycine;   SMILES=C(=O)([C@@H](N)CC#C)O
 xref: CAS:23235-01-0 "ChemIDplus";   PDBeChem:LPG;   PMID:23772385 "Europe PMC";   PMID:30867596 "Europe PMC";   PMID:387077 "Europe PMC";   PMID:3994731 "Europe PMC";   PMID:7094918 "Europe PMC";   PMID:7364752 "Europe PMC";   PMID:944577 "Europe PMC"
 cyclic_relationship: is_tautomer_of CHEBI:143285

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  CHEBI ontology 19728
    chemical entity 19726
      molecular entity 19723
        polyatomic entity 19640
          molecule 19452
            organic molecule 19417
              acetylenic compound 5778
                terminal acetylenic compound 5542
                  L-propargylglycine 0
                    L-beta-ethynylserine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        amino acid 12443
                                          alpha-amino acid 7646
                                            L-alpha-amino acid 7311
                                              non-proteinogenic L-alpha-amino acid 579
                                                L-propargylglycine 0
                                                  L-beta-ethynylserine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.