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ONTOLOGY REPORT - ANNOTATIONS


Term:tiamulin
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Accession:CHEBI:44137 term browser browse the term
Definition:A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae.
Synonyms:exact_synonym: (3aS,4R,5S,6S,8R,9R,9aR,10R)-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-6-vinyldecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate
 related_synonym: Formula=C28H47NO4S;   InChI=1S/C28H47NO4S/c1-8-26(6)17-22(33-23(31)18-34-16-15-29(9-2)10-3)27(7)19(4)11-13-28(20(5)25(26)32)14-12-21(30)24(27)28/h8,19-20,22,24-25,32H,1,9-18H2,2-7H3/t19-,20+,22-,24+,25+,26-,27+,28+/m1/s1;   InChIKey=UURAUHCOJAIIRQ-QGLSALSOSA-N;   SMILES=CCN(CC)CCSCC(=O)O[C@@H]1C[C@@](C)(C=C)[C@@H](O)[C@H](C)[C@]23CCC(=O)[C@H]2[C@@]1(C)[C@H](C)CC3;   tiamulina;   tiamuline;   tiamulinum
 alt_id: CHEBI:29695
 xref: CAS:55297-95-5 "ChemIDplus";   CAS:55297-95-5 "KEGG COMPOUND";   KEGG:C12065;   KEGG:D06127
 xref_mesh: MESH:C014224
 xref: PDBeChem:MUL;   PMID:15013817 "Europe PMC";   PMID:16253666 "Europe PMC";   PMID:25592328 "Europe PMC";   PMID:3170319 "Europe PMC";   PMID:3686511 "Europe PMC";   Patent:DE2248237;   Patent:US3919290;   Reaxys:7348837 "Reaxys";   Wikipedia:Tiamulin


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tiamulin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        antimicrobial agent 17215
          antibacterial agent 12930
            antibacterial drug 3089
              tiamulin 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      ketone 15918
                                        cyclic ketone 13351
                                          Pleuromutilin 1
                                            tiamulin 1
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