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ONTOLOGY REPORT - ANNOTATIONS


Term:nitrofurazone
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Accession:CHEBI:44368 term browser browse the term
Definition:A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcers, wounds and skin infections.
Synonyms:exact_synonym: 2-[(5-nitro-2-furyl)methylene]hydrazinecarboxamide
 related_synonym: (5-nitro-2-furfurylidenamino)urea;   1-(5-nitro-2-furfurylidene)semicarbazide;   5-Nitro-2-furaldehyde semicarbazone;   5-nitrofuraldehyde semicarbazide;   5-nitrofuran-2-carbaldehyde semicarbazone;   5-nitrofurfural semicarbazone;   Alfucin;   Amifur;   Chemofuran;   Formula=C6H6N4O4;   Furacillin;   Furacin;   Furacinetten;   Furacoccid;   Furaldon;   Furazol W;   Furesol;   InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11);   InChIKey=IAIWVQXQOWNYOU-UHFFFAOYSA-N;   Mammex;   Mastofuran;   Monafuracin;   Nifuzon;   SMILES=NC(=O)NN=Cc1ccc(o1)[N+]([O-])=O;   nitrofural;   nitrofuralum
 alt_id: CHEBI:7592
 xref: CAS:59-87-0 "ChemIDplus";   CAS:59-87-0 "KEGG COMPOUND";   CAS:59-87-0 "NIST Chemistry WebBook";   DrugBank:DB00336;   Drug_Central:1950 "DrugCentral";   HMDB:HMDB0014480;   KEGG:C08042;   KEGG:D00862;   LINCS:LSM-3779
 xref_mesh: MESH:D009583
 xref: PDBeChem:NFZ;   PMID:14703769 "Europe PMC";   PMID:2137394 "Europe PMC";   PMID:22355582 "Europe PMC";   PMID:2292799 "Europe PMC";   PMID:23957951 "Europe PMC";   Patent:US2416234;   Patent:US2927110;   Reaxys:86403 "Reaxys";   Wikipedia:Nitrofural


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nitrofurazone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Por cytochrome p450 oxidoreductase JBrowse link 12 23,998,411 24,017,063 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Tgfa transforming growth factor alpha JBrowse link 4 117,961,877 118,045,923 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          nitrofuran antibiotic 43
            nitrofurazone 14
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                monocarboxylic acid amide 14163
                                                  urea 4949
                                                    ureas 4946
                                                      semicarbazide 40
                                                        semicarbazone 14
                                                          nitrofurazone 14
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