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Accession:CHEBI:45716 term browser browse the term
Definition:A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL).
Synonyms:exact_synonym: N-hydroxy-N'-phenyloctanediamide
 related_synonym: Formula=C14H20N2O3;   InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18);   InChIKey=WAEXFXRVDQXREF-UHFFFAOYSA-N;   SAHA;   SHH;   SMILES=ONC(=O)CCCCCCC(=O)Nc1ccccc1;   Suberanilohydroxamic acid;   Zolinza;   octanedioic acid hydroxyamide phenylamide;   suberoylanilide hydroxamic acid;   vorinostatum
 xref: CAS:149647-78-9 "ChemIDplus";   DrugBank:DB02546;   Drug_Central:4124 "DrugCentral";   HMDB:HMDB0015568;   KEGG:D06320;   LINCS:LSM-3828
 xref_mesh: MESH:C111237
 xref: PDBeChem:SHH;   PMID:21657958 "Europe PMC";   PMID:22887890 "Europe PMC";   PMID:23320102 "Europe PMC";   PMID:23348693 "Europe PMC";   PMID:23708756 "Europe PMC";   PMID:23758082 "Europe PMC";   PMID:23820962 "Europe PMC";   PMID:23864881 "Europe PMC";   Patent:CN102641261;   Patent:KR20110045493;   Patent:NZ592686;   Patent:US2011039937;   Patent:WO2008106524;   Reaxys:7213017 "Reaxys";   Wikipedia:Vorinostat

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vorinostat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CASQ1 calsequestrin 1 JBrowse link 38 22,012,060 22,020,430 RGD:6480464
G HSP70 heat shock protein 70 JBrowse link 12 1,285,282 1,287,670 RGD:6480464
G TNNI3K TNNI3 interacting kinase JBrowse link 6 71,825,853 72,107,832 RGD:6480464

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  CHEBI ontology 223
    role 223
      biological role 223
        biochemical role 185
          apoptosis inducer 17
            vorinostat 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 223
    subatomic particle 223
      composite particle 223
        hadron 223
          baryon 223
            nucleon 223
              atomic nucleus 223
                atom 223
                  main group element atom 216
                    p-block element atom 216
                      carbon group element atom 205
                        carbon atom 204
                          organic molecular entity 204
                            organic group 153
                              organic divalent group 152
                                organodiyl group 152
                                  carbonyl group 152
                                    carbonyl compound 152
                                      carboxylic acid 112
                                        carboacyl group 47
                                          univalent carboacyl group 47
                                            carbamoyl group 44
                                              carboxamide 44
                                                dicarboxylic acid amide 4
                                                  dicarboxylic acid diamide 3
                                                    vorinostat 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.