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Accession:CHEBI:46261 term browser browse the term
Definition:A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing.
Synonyms:exact_synonym: 1-phenylthiourea
 related_synonym: 1-phenyl-2-thiourea;   Formula=C7H8N2S;   InChI=1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10);   InChIKey=FULZLIGZKMKICU-UHFFFAOYSA-N;   PTC;   PTU;   PhNHC(S)NH2;   PhNHCSNH2;   SMILES=NC(=S)Nc1ccccc1;   alpha-phenylthiourea;   monophenyl thiourea;   phenyl-2-thiourea;   phenylthiocarbamide;   phenylthiourea
 xref: CAS:103-85-5 "ChemIDplus";   CAS:103-85-5 "NIST Chemistry WebBook";   DrugBank:DB03694
 xref_mesh: MESH:D010670
 xref: MetaCyc:CPD-7084;   PDBeChem:URS;   PMID:13914407 "Europe PMC";   PMID:20484932 "Europe PMC";   PMID:21534859 "Europe PMC";   PMID:22656649 "Europe PMC";   PMID:22690050 "Europe PMC";   PMID:22761952 "Europe PMC";   PMID:23598058 "Europe PMC";   PMID:25962731 "Europe PMC";   PMID:26005654 "Europe PMC";   PMID:26226450 "Europe PMC";   PMID:27402661 "Europe PMC";   PMID:4113332 "Europe PMC";   PMID:834304 "Europe PMC";   Reaxys:907309 "Reaxys";   Wikipedia:Phenylthiocarbamide

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N-phenylthiourea term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Car1 carbonic anhydrase 1 JBrowse link 2 88,185,204 88,227,486 RGD:6480464
G Car2 carbonic anhydrase 2 JBrowse link 2 88,097,740 88,112,868 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Fmo3 flavin containing dimethylaniline monoxygenase 3 JBrowse link 13 80,837,418 80,856,214 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mitf melanocyte inducing transcription factor JBrowse link 4 130,172,484 130,425,496 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tas2r138 taste receptor, type 2, member 138 JBrowse link 4 68,831,221 68,832,216 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19764
    role 19711
      chemical role 19227
        antioxidant 14142
          thiourea 34
            N-phenylthiourea 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19764
    subatomic particle 19762
      composite particle 19762
        hadron 19762
          baryon 19762
            nucleon 19762
              atomic nucleus 19762
                atom 19762
                  main group element atom 19646
                    p-block element atom 19646
                      carbon group element atom 19540
                        carbon atom 19529
                          organic molecular entity 19529
                            organic group 18432
                              organic divalent group 18423
                                organodiyl group 18423
                                  carbonyl group 18311
                                    carbonyl compound 18311
                                      carboxylic acid 17978
                                        carboacyl group 17095
                                          univalent carboacyl group 17095
                                            carbamoyl group 16817
                                              carboxamide 16817
                                                monocarboxylic acid amide 14173
                                                  urea 4966
                                                    ureas 4964
                                                      thiourea 34
                                                        N-phenylthiourea 11
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.