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ONTOLOGY REPORT - ANNOTATIONS


Term:disopyramide
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Accession:CHEBI:4657 term browser browse the term
Definition:A monocarboxylic acid amide that is butanamide substituted by a diisopropylamino group at position 4, a phenyl group at position 2 and a pyridin-2-yl group at position 2. It is used as a anti-arrhythmia drug.
Synonyms:exact_synonym: 4-(diisopropylamino)-2-phenyl-2-pyridin-2-ylbutanamide
 related_synonym: Formula=C21H29N3O;   InChI=1S/C21H29N3O/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);   InChIKey=UVTNFZQICZKOEM-UHFFFAOYSA-N;   SMILES=CC(C)N(CCC(C(N)=O)(c1ccccc1)c1ccccn1)C(C)C;   alpha-(2-(Diisopropylamino)ethyl)-alpha-phenyl-2-pyridineacetamide;   disopiramida;   disopyramidum;   gamma-Diisopropylamino-alpha-phenyl-alpha-(2-pyridyl)butyramide
 xref: Beilstein:492056 "Beilstein";   CAS:3737-09-5 "ChemIDplus";   DrugBank:DB00280;   Drug_Central:926 "DrugCentral";   KEGG:C06965;   KEGG:D00303;   LINCS:LSM-1439
 xref_mesh: MESH:D004206
 xref: PMID:16842817 "Europe PMC";   PMID:24502246 "Europe PMC";   Patent:BE617730;   Patent:US3225054;   Reaxys:492056 "Reaxys";   Wikipedia:Disopyramide


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disopyramide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Asah1 N-acylsphingosine amidohydrolase 1 JBrowse link 16 53,998,604 54,030,006 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        pharmaceutical 19214
          drug 19214
            cardiovascular drug 7564
              anti-arrhythmia drug 879
                disopyramide 6
                  disopyramide phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                monocarboxylic acid amide 14162
                                                  disopyramide 6
                                                    disopyramide phosphate 0
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