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ONTOLOGY REPORT - ANNOTATIONS


Term:oxadiazole
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Accession:CHEBI:46685 term browser browse the term
Synonyms:related_synonym: oxadiazoles


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1,3,4-oxadiazoles term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
azilsartan term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
GR 127935 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
GSK690693 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 JBrowse link 16 68,954,860 68,968,248 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tsc2 TSC complex subunit 2 JBrowse link 10 13,962,006 13,996,684 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    chemical entity 19726
      atom 19724
        nonmetal atom 19597
          nitrogen atom 18386
            nitrogen molecular entity 18386
              organonitrogen compound 18174
                organonitrogen heterocyclic compound 17188
                  oxadiazole 17
                    1,2,4-oxadiazole + 7
                    1,2,5-oxadiazole + 9
                    1,3,4-oxadiazoles + 1
                    1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester 0
                    1-[3-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-1-butanone 0
                    1-ethyl-4-[[methyl-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidinone 0
                    2,5-dichloro-N-methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]benzenesulfonamide 0
                    2-(2-methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                    2-(4-methoxyphenyl)-N-[4-[5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                    2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzamide 0
                    2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    3-(2-chlorophenyl)-N-cyclohexyl-5-methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-4-isoxazolecarboxamide 0
                    3-(2-methoxy-6-methyl-3-pyridinyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                    3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester 0
                    3-(4-bromophenyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole 0
                    3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole 0
                    3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole 0
                    3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole 0
                    3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-pyridinyl)propanamide 0
                    3-[3-(4-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                    3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-methylphenyl)propanamide 0
                    3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamide 0
                    3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-cyclopropylpropanamide 0
                    3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                    3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-methylpropanamide 0
                    3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    3-phenyl-5-[[[4-phenyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole 0
                    3-phenyl-5-thioxo-2,5-dihydro-1,2,3-oxadiazol-3-ium 0
                    4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-[5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                    4-morpholinyl-[4-[3-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone 0
                    5-(2,3-dihydrobenzofuran-5-yl)-3-(4-fluorophenyl)-1,2,4-oxadiazole 0
                    5-(2-chloro-4-fluorophenyl)-3-(2-pyrazinyl)-1,2,4-oxadiazole 0
                    5-(2-ethoxyphenyl)-3-(2-methoxy-6-methyl-3-pyridinyl)-1,2,4-oxadiazole 0
                    5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                    5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                    5-(3,5-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole 0
                    5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                    5-(5-bromo-2-chlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                    5-(6-chloro-3-pyridinyl)-3-(3-methoxyphenyl)-1,2,4-oxadiazole 0
                    5-[(4-methyl-1-piperidinyl)methyl]-3-phenyl-1,2,4-oxadiazole 0
                    5-[(4-methylphenoxy)methyl]-3-phenyl-1,2,4-oxadiazole 0
                    5-[4-phenyl-5-(trifluoromethyl)-2-thiophenyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 0
                    5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole 0
                    5-chloro-2-methoxy-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-ylbenzamide 0
                    AZD1979 + 0
                    AZD1979 oxetane hydrolysis product 0
                    N,2-dimethyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-3-furancarboxamide 0
                    N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine 0
                    N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinecarboxamide 0
                    N-(5-chloro-2,4-dimethoxyphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-(2,3,5-trimethylphenoxy)acetamide 0
                    N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide 0
                    N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-[4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-(4-methoxyphenyl)acetamide 0
                    N-ethyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(phenylmethyl)propanamide 0
                    N-ethyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-ethyl-N-(2-ethylphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-methyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                    N-tert-butyl-2-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzamide 0
                    [2-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-(1-pyrrolidinyl)methanone 0
                    butalamine 0
                    imolamine 0
                    opicapone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic molecule 19417
                              organic cyclic compound 19184
                                organic heterocyclic compound 18262
                                  organic heteromonocyclic compound 16347
                                    oxadiazole 17
                                      1,2,4-oxadiazole + 7
                                      1,2,5-oxadiazole + 9
                                      1,3,4-oxadiazoles + 1
                                      1-(4-amino-1,2,5-oxadiazol-3-yl)-5-[(2-pyridinylthio)methyl]-4-triazolecarboxylic acid propan-2-yl ester 0
                                      1-[3-[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinyl]-1-butanone 0
                                      1-ethyl-4-[[methyl-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methyl]amino]methyl]-2-pyrrolidinone 0
                                      2,5-dichloro-N-methyl-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]benzenesulfonamide 0
                                      2-(2-methoxyphenyl)-N-[4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                                      2-(4-methoxyphenyl)-N-[4-[5-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazol-3-yl]phenyl]acetamide 0
                                      2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzamide 0
                                      2-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      3-(2-chlorophenyl)-N-cyclohexyl-5-methyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-4-isoxazolecarboxamide 0
                                      3-(2-methoxy-6-methyl-3-pyridinyl)-5-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                                      3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazole-5-carboxylic acid ethyl ester 0
                                      3-(4-bromophenyl)-5-(3,5-dimethoxyphenyl)-1,2,4-oxadiazole 0
                                      3-(4-methoxyphenyl)-5-(2-phenylethyl)-1,2,4-oxadiazole 0
                                      3-(4-methoxyphenyl)-5-(4-methylphenyl)-1,2,4-oxadiazole 0
                                      3-(5-bromo-2-furanyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole 0
                                      3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-pyridinyl)propanamide 0
                                      3-[3-(4-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                                      3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-N-(3-methylphenyl)propanamide 0
                                      3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)propanamide 0
                                      3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-cyclopropylpropanamide 0
                                      3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-ethylpropanamide 0
                                      3-[3-(4-tert-butylphenyl)-1,2,4-oxadiazol-5-yl]-N-methylpropanamide 0
                                      3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      3-phenyl-5-[[[4-phenyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-1,2,4-oxadiazole 0
                                      3-phenyl-5-thioxo-2,5-dihydro-1,2,3-oxadiazol-3-ium 0
                                      4-[5-(2-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(2-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(3-chlorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(4-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-(4-methoxyphenyl)-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-[5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid 0
                                      4-morpholinyl-[4-[3-[4-(4-morpholinylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-piperidinyl]methanone 0
                                      5-(2,3-dihydrobenzofuran-5-yl)-3-(4-fluorophenyl)-1,2,4-oxadiazole 0
                                      5-(2-chloro-4-fluorophenyl)-3-(2-pyrazinyl)-1,2,4-oxadiazole 0
                                      5-(2-ethoxyphenyl)-3-(2-methoxy-6-methyl-3-pyridinyl)-1,2,4-oxadiazole 0
                                      5-(3,4-diethoxyphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                                      5-(3,5-dimethoxyphenyl)-3-(2-methoxyphenyl)-1,2,4-oxadiazole 0
                                      5-(3,5-dimethoxyphenyl)-3-phenyl-1,2,4-oxadiazole 0
                                      5-(3-chloro-4-methylphenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                                      5-(5-bromo-2-chlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole 0
                                      5-(6-chloro-3-pyridinyl)-3-(3-methoxyphenyl)-1,2,4-oxadiazole 0
                                      5-[(4-methyl-1-piperidinyl)methyl]-3-phenyl-1,2,4-oxadiazole 0
                                      5-[(4-methylphenoxy)methyl]-3-phenyl-1,2,4-oxadiazole 0
                                      5-[4-phenyl-5-(trifluoromethyl)-2-thiophenyl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole 0
                                      5-[[(1-cyclohexyl-5-tetrazolyl)thio]methyl]-3-phenyl-1,2,4-oxadiazole 0
                                      5-chloro-2-methoxy-N-[[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-N-propan-2-ylbenzamide 0
                                      AZD1979 + 0
                                      AZD1979 oxetane hydrolysis product 0
                                      N,2-dimethyl-N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-3-furancarboxamide 0
                                      N,N-diethyl-2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethanamine 0
                                      N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-(4-chlorophenyl)-4-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-piperidinecarboxamide 0
                                      N-(5-chloro-2,4-dimethoxyphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-(2,3,5-trimethylphenoxy)acetamide 0
                                      N-[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]-2-thiophenecarboxamide 0
                                      N-[2-(3,4-dihydro-1H-isoquinolin-2-yl)ethyl]-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-[4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]phenyl]-2-(4-methoxyphenyl)acetamide 0
                                      N-ethyl-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]-N-(phenylmethyl)propanamide 0
                                      N-ethyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-ethyl-N-(2-ethylphenyl)-3-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-methyl-3-[3-(4-propan-2-ylphenyl)-1,2,4-oxadiazol-5-yl]propanamide 0
                                      N-tert-butyl-2-[3-(2-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzamide 0
                                      [2-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]phenyl]-(1-pyrrolidinyl)methanone 0
                                      butalamine 0
                                      imolamine 0
                                      opicapone 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.