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ONTOLOGY REPORT - ANNOTATIONS


Term:edrophonium chloride
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Accession:CHEBI:4759 term browser browse the term
Definition:The chloride salt of edrophonium. A reversible inhibitor of cholinesterase with a rapid onset (30-60 seconds after injection) but a short duration of action (5-15 minutes), it is used in myasthenia gravis both diagnostically and to distinguish between under- or over-treatment with other anticholinesterases. It has also been used for the reversal of neuromuscular blockade in anaesthesia, and for the management of poisoning due to tetrodotoxin, a neuromuscular blocking toxin found in puffer fish and other marine animals.
Synonyms:exact_synonym: N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride
 related_synonym: (3-hydroxyphenyl)dimethylethylammonium chloride;   3-hydroxy-N,N-dimethyl-N-ethylanilinium chloride;   Formula=C10H16ClNO;   InChI=1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H;   InChIKey=BXKDSDJJOVIHMX-UHFFFAOYSA-N;   N-ethyl-3-hydroxy-N,N-dimethylbenzenaminium chloride;   SMILES=[Cl-].CC[N+](C)(C)c1cccc(O)c1;   chlorure d'edrophonium;   cloruro de edrofonio;   edrophonii chloridum;   ethyl(m-hydroxyphenyl)dimethylammonium chloride
 alt_id: CHEBI:267875
 xref: Beilstein:3748734;   CAS:116-38-1;   DrugBank:DB01010;   KEGG:D00994;   PMID:7488499;   Patent:US2647924;   Wikipedia:Edrophonium


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  CHEBI ontology 19758
    role 19705
      application 19359
        pharmaceutical 19228
          diagnostic agent 654
            edrophonium chloride 0
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  CHEBI ontology 19758
    subatomic particle 19756
      composite particle 19756
        hadron 19756
          baryon 19756
            nucleon 19756
              atomic nucleus 19756
                atom 19756
                  main group element atom 19641
                    main group molecular entity 19641
                      s-block molecular entity 19403
                        hydrogen molecular entity 19392
                          hydrides 18362
                            inorganic hydride 17222
                              pnictogen hydride 17186
                                nitrogen hydride 17020
                                  ammonium 8227
                                    ammonium ion derivative 8222
                                      ammonium compound 5093
                                        organoammonium salt 415
                                          quaternary ammonium salt 300
                                            edrophonium chloride 0
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