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ONTOLOGY REPORT - ANNOTATIONS


Term:ellagic acid
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Accession:CHEBI:4775 term browser browse the term
Definition:An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.
Synonyms:exact_synonym: 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
 related_synonym: 2,3,7,8-tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione;   4,4',5,5',6,6'-hexahydroxydiphenic acid 2,6,2',6'-dilactone;   Ellagsaeure;   Formula=C14H6O8;   InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H;   InChIKey=AFSDNFLWKVMVRB-UHFFFAOYSA-N;   Lagistase;   SMILES=Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O;   acide ellagique;   acido elagico;   acidum ellagicum;   benzoaric acid
 xref: Beilstein:47549 "Beilstein";   CAS:476-66-4 "ChemIDplus";   CAS:476-66-4 "KEGG COMPOUND";   HMDB:HMDB0002899;   KEGG:C10788;   KNApSAcK:C00011153;   LINCS:LSM-36455
 xref_mesh: MESH:D004610
 xref: PDBeChem:REF;   PMID:10445164 "Europe PMC";   PMID:10999626 "Europe PMC";   PMID:11902978 "Europe PMC";   PMID:15659385 "Europe PMC";   PMID:15936648 "Europe PMC";   PMID:16317787 "Europe PMC";   PMID:17379263 "Europe PMC";   PMID:17940513 "Europe PMC";   PMID:18155344 "Europe PMC";   PMID:19015354 "Europe PMC";   PMID:19684079 "Europe PMC";   PMID:20034460 "Europe PMC";   PMID:21922312 "Europe PMC";   PMID:22173652 "Europe PMC";   PMID:22538930 "Europe PMC";   PMID:22626975 "Europe PMC";   PMID:23058930 "Europe PMC";   PMID:23060566 "Europe PMC";   PMID:23092326 "Europe PMC";   PMID:23322372 "Europe PMC";   PMID:25438234 "Europe PMC";   PMID:7644381 "Europe PMC";   Reaxys:47549 "Reaxys";   Wikipedia:Ellagic_acid


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ellagic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acp3 acid phosphatase 3 JBrowse link 8 112,838,574 112,884,062 RGD:6480464
G Aifm1 apoptosis inducing factor, mitochondria associated 1 JBrowse link X 135,304,063 135,343,062 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Alkbh2 alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase JBrowse link 12 48,257,575 48,262,244 RGD:6480464
G Apaf1 apoptotic peptidase activating factor 1 JBrowse link 7 31,699,309 31,784,192 RGD:6480464
G Ascl1 achaete-scute family bHLH transcription factor 1 JBrowse link 7 28,038,662 28,040,504 RGD:6480464
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:6480464
G Atf3 activating transcription factor 3 JBrowse link 13 109,817,892 109,849,632 RGD:6480464
G Atg5 autophagy related 5 JBrowse link 20 49,301,783 49,393,147 RGD:6480464
G Bad BCL2-associated agonist of cell death JBrowse link 1 222,198,516 222,207,459 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:6480464
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit JBrowse link 6 137,762,230 137,808,573 RGD:6480464
G Calr calreticulin JBrowse link 19 25,956,771 25,961,666 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Daxx death-domain associated protein JBrowse link 20 5,480,103 5,485,962 RGD:6480464
G Dffa DNA fragmentation factor subunit alpha JBrowse link 5 165,922,893 165,935,822 RGD:6480464
G E4f1 E4F transcription factor 1 JBrowse link 10 13,812,335 13,835,847 RGD:6480464
G Egr3 early growth response 3 JBrowse link 15 51,756,683 51,762,080 RGD:6480464
G Endog endonuclease G JBrowse link 3 8,741,833 8,744,414 RGD:6480464
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:6480464
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 5 128,923,809 129,022,268 RGD:6480464
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit JBrowse link 10 89,104,026 89,139,978 RGD:6480464
G F12 coagulation factor XII JBrowse link 17 9,736,577 9,744,420 RGD:6480464
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:6480464
G Flna filamin A JBrowse link X 156,460,785 156,487,245 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gal galanin and GMAP prepropeptide JBrowse link 1 218,653,059 218,657,922 RGD:6480464
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 17 42,085,027 42,131,344 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gsta4 glutathione S-transferase alpha 4 JBrowse link 8 85,497,557 85,514,732 RGD:6480464
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:6480464
G Gtf2e2 general transcription factor IIE subunit 2 JBrowse link 16 62,113,846 62,164,339 RGD:6480464
G Gtf2h4 general transcription factor 2H subunit 4 JBrowse link 20 3,582,688 3,588,373 RGD:6480464
G Gusb glucuronidase, beta JBrowse link 12 30,202,066 30,215,583 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hlcs holocarboxylase synthetase JBrowse link 11 34,357,372 34,537,798 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hras HRas proto-oncogene, GTPase JBrowse link 1 214,178,404 214,181,841 RGD:6480464
G Ier2 immediate early response 2 JBrowse link 19 25,774,146 25,775,670 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igfbp2 insulin-like growth factor binding protein 2 JBrowse link 9 80,118,029 80,144,804 RGD:6480464
G Igfbp4 insulin-like growth factor binding protein 4 JBrowse link 10 86,950,555 86,962,563 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1r1 interleukin 1 receptor type 1 JBrowse link 9 46,962,291 47,038,139 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Inpp5d inositol polyphosphate-5-phosphatase D JBrowse link 9 94,745,220 94,850,778 RGD:6480464
G Iqgap2 IQ motif containing GTPase activating protein 2 JBrowse link 2 26,161,628 26,439,067 RGD:6480464
G Irf9 interferon regulatory factor 9 JBrowse link 15 34,282,936 34,288,981 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Litaf lipopolysaccharide-induced TNF factor JBrowse link 10 4,753,546 4,763,272 RGD:6480464
G Map1a microtubule-associated protein 1A JBrowse link 3 113,251,918 113,272,193 RGD:6480464
G Map3k1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 2 43,329,516 43,393,203 RGD:6480464
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Mapk9 mitogen-activated protein kinase 9 JBrowse link 10 35,333,859 35,374,364 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Mmd monocyte to macrophage differentiation-associated JBrowse link 10 77,687,964 77,783,737 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkb2 nuclear factor kappa B subunit 2 JBrowse link 1 266,050,634 266,059,277 RGD:6480464
G Nnat neuronatin JBrowse link 3 154,043,873 154,046,334 RGD:6480464
G Nop56 NOP56 ribonucleoprotein JBrowse link 3 122,803,726 122,808,564 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Npas2 neuronal PAS domain protein 2 JBrowse link 9 45,901,262 46,081,880 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Parg poly (ADP-ribose) glycohydrolase JBrowse link 16 8,350,168 8,457,999 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Pdia2 protein disulfide isomerase family A, member 2 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:6480464
G Plp2 proteolipid protein 2 JBrowse link X 15,679,254 15,682,653 RGD:6480464
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:6480464
G Ppard peroxisome proliferator-activated receptor delta JBrowse link 20 7,818,289 7,883,482 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:6480464
G Ptn pleiotrophin JBrowse link 4 64,239,156 64,330,996 RGD:6480464
G Ptprn2 protein tyrosine phosphatase, receptor type N2 JBrowse link 6 144,384,773 145,133,042 RGD:6480464
G Ran RAN, member RAS oncogene family JBrowse link 12 31,319,556 31,324,105 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Reck reversion-inducing-cysteine-rich protein with kazal motifs JBrowse link 5 59,348,568 59,415,169 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rgs5 regulator of G-protein signaling 5 JBrowse link 13 87,966,820 88,002,831 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Septin2 septin 2 JBrowse link 9 100,624,876 100,658,053 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sod3 superoxide dismutase 3 JBrowse link 14 60,958,583 60,971,143 RGD:6480464
G Star steroidogenic acute regulatory protein JBrowse link 16 71,036,204 71,040,847 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Taf1c TATA-box binding protein associated factor, RNA polymerase 1 subunit C JBrowse link 19 52,246,061 52,252,642 RGD:6480464
G Tcf12 transcription factor 12 JBrowse link 8 78,343,634 78,657,738 RGD:6480464
G Tert telomerase reverse transcriptase JBrowse link 1 32,250,876 32,275,330 RGD:6480464
G Tfam transcription factor A, mitochondrial JBrowse link 20 18,594,057 18,606,106 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnnt2 troponin T2, cardiac type JBrowse link 13 52,662,974 52,680,992 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ugp2 UDP-glucose pyrophosphorylase 2 JBrowse link 14 106,208,174 106,249,322 RGD:6480464
G Usp4 ubiquitin specific peptidase 4 JBrowse link 8 117,126,692 117,171,012 RGD:6480464
G Wars1 tryptophanyl-tRNA synthetase 1 JBrowse link 6 132,771,026 132,802,262 RGD:6480464
G Wee1 WEE1 G2 checkpoint kinase JBrowse link 1 174,765,228 174,790,882 RGD:6480464
G Zbtb16 zinc finger and BTB domain containing 16 JBrowse link 8 52,980,226 53,146,765 RGD:6480464
G Zmym2 zinc finger MYM-type containing 2 JBrowse link 15 37,156,250 37,229,803 RGD:6480464
corilagin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      chemical role 19171
        antioxidant 14106
          ellagic acid 122
            ellagitannin + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        aromatic carboxylic acid 10745
                                          benzoic acids 10711
                                            benzoic acid 3478
                                              hydroxybenzoic acid 2852
                                                trihydroxybenzoic acid 2258
                                                  gallic acid 2244
                                                    ellagic acid 122
                                                      ellagitannin + 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.