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ONTOLOGY REPORT - ANNOTATIONS


Term:ellagic acid
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Accession:CHEBI:4775 term browser browse the term
Definition:An organic heterotetracyclic compound resulting from the formal dimerisation of gallic acid by oxidative aromatic coupling with intramolecular lactonisation of both carboxylic acid groups of the resulting biaryl. It is found in many fruits and vegetables, including raspberries, strawberries, cranberries, and pomegranates.
Synonyms:exact_synonym: 2,3,7,8-tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione
 related_synonym: 2,3,7,8-tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione;   4,4',5,5',6,6'-hexahydroxydiphenic acid 2,6,2',6'-dilactone;   Ellagsaeure;   Formula=C14H6O8;   InChI=1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H;   InChIKey=AFSDNFLWKVMVRB-UHFFFAOYSA-N;   Lagistase;   SMILES=Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O;   acide ellagique;   acido elagico;   acidum ellagicum;   benzoaric acid
 xref: Beilstein:47549 "Beilstein";   CAS:476-66-4 "ChemIDplus";   CAS:476-66-4 "KEGG COMPOUND";   HMDB:HMDB0002899;   KEGG:C10788;   KNApSAcK:C00011153;   LINCS:LSM-36455
 xref_mesh: MESH:D004610
 xref: PDBeChem:REF;   PMID:10445164 "Europe PMC";   PMID:10999626 "Europe PMC";   PMID:11902978 "Europe PMC";   PMID:15659385 "Europe PMC";   PMID:15936648 "Europe PMC";   PMID:16317787 "Europe PMC";   PMID:17379263 "Europe PMC";   PMID:17940513 "Europe PMC";   PMID:18155344 "Europe PMC";   PMID:19015354 "Europe PMC";   PMID:19684079 "Europe PMC";   PMID:20034460 "Europe PMC";   PMID:21922312 "Europe PMC";   PMID:22173652 "Europe PMC";   PMID:22538930 "Europe PMC";   PMID:22626975 "Europe PMC";   PMID:23058930 "Europe PMC";   PMID:23060566 "Europe PMC";   PMID:23092326 "Europe PMC";   PMID:23322372 "Europe PMC";   PMID:25438234 "Europe PMC";   PMID:7644381 "Europe PMC";   Reaxys:47549 "Reaxys";   Wikipedia:Ellagic_acid


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ellagic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACP3 acid phosphatase 3 JBrowse link 3 132,317,403 132,368,765 RGD:6480464
G AIFM1 apoptosis inducing factor mitochondria associated 1 JBrowse link X 130,129,362 130,165,887 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G ALB albumin JBrowse link 4 73,404,287 73,421,482 RGD:6480464
G ALKBH2 alkB homolog 2, alpha-ketoglutarate dependent dioxygenase JBrowse link 12 109,088,188 109,093,631 RGD:6480464
G APAF1 apoptotic peptidase activating factor 1 JBrowse link 12 98,645,141 98,735,433 RGD:6480464
G ASCL1 achaete-scute family bHLH transcription factor 1 JBrowse link 12 102,957,674 102,960,513 RGD:6480464
G ASNS asparagine synthetase (glutamine-hydrolyzing) JBrowse link 7 97,851,677 97,928,441 RGD:6480464
G ATF3 activating transcription factor 3 JBrowse link 1 212,565,334 212,620,777 RGD:6480464
G ATG5 autophagy related 5 JBrowse link 6 106,184,476 106,325,820 RGD:6480464
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BMP6 bone morphogenetic protein 6 JBrowse link 6 7,726,099 7,881,728 RGD:6480464
G BRF1 BRF1 RNA polymerase III transcription initiation factor subunit JBrowse link 14 105,209,286 105,315,577 RGD:6480464
G CALR calreticulin JBrowse link 19 12,938,609 12,944,489 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CD14 CD14 molecule JBrowse link 5 140,631,728 140,633,701 RGD:6480464
G CDK1 cyclin dependent kinase 1 JBrowse link 10 60,778,331 60,794,852 RGD:6480464
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:6480464
G CTSD cathepsin D JBrowse link 11 1,752,755 1,763,927 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 JBrowse link 15 74,719,542 74,725,528 RGD:6480464
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 JBrowse link 2 38,067,603 38,076,181 RGD:6480464
G DAXX death domain associated protein JBrowse link 6 33,318,558 33,323,016 RGD:6480464
G DFFA DNA fragmentation factor subunit alpha JBrowse link 1 10,456,522 10,472,529 RGD:6480464
G E4F1 E4F transcription factor 1 JBrowse link 16 2,223,488 2,235,742 RGD:6480464
G EGR3 early growth response 3 JBrowse link 8 22,687,659 22,693,480 RGD:6480464
G ENDOG endonuclease G JBrowse link 9 128,818,402 128,822,676 RGD:6480464
G EP300 E1A binding protein p300 JBrowse link 22 41,092,592 41,180,077 RGD:6480464
G EPS15 epidermal growth factor receptor pathway substrate 15 JBrowse link 1 51,354,263 51,519,275 RGD:6480464
G EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit JBrowse link 17 42,700,275 42,745,078 RGD:6480464
G F12 coagulation factor XII JBrowse link 5 177,402,138 177,409,576 RGD:6480464
G FGFR1 fibroblast growth factor receptor 1 JBrowse link 8 38,411,138 38,468,834 RGD:6480464
G FLNA filamin A JBrowse link X 154,348,531 154,374,638 RGD:6480464
G FN1 fibronectin 1 JBrowse link 2 215,360,440 215,436,167 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 14 75,278,828 75,282,230 RGD:6480464
G G6PD glucose-6-phosphate dehydrogenase JBrowse link X 154,531,390 154,547,569 RGD:6480464
G GAL galanin and GMAP prepropeptide JBrowse link 11 68,684,544 68,691,175 RGD:6480464
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 JBrowse link 6 24,423,969 24,495,232 RGD:6480464
G GPT glutamic--pyruvic transaminase JBrowse link 8 144,502,217 144,507,174 RGD:6480464
G GPX1 glutathione peroxidase 1 JBrowse link 3 49,357,171 49,358,600 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 8 30,678,061 30,727,999 RGD:6480464
G GSTA4 glutathione S-transferase alpha 4 JBrowse link 6 52,977,952 52,995,332 RGD:6480464
G GSTT1 glutathione S-transferase theta 1 RGD:6480464
G GTF2E2 general transcription factor IIE subunit 2 JBrowse link 8 30,578,318 30,658,241 RGD:6480464
G GTF2H4 general transcription factor IIH subunit 4 JBrowse link 6 30,908,207 30,914,106 RGD:6480464
G GUSB glucuronidase beta JBrowse link 7 65,960,684 65,982,230 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G HLCS holocarboxylase synthetase JBrowse link 21 36,748,625 36,990,255 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 532,242 535,576 RGD:6480464
G IER2 immediate early response 2 JBrowse link 19 13,150,411 13,154,911 RGD:6480464
G IFNG interferon gamma JBrowse link 12 68,154,768 68,159,740 RGD:6480464
G IGFBP2 insulin like growth factor binding protein 2 JBrowse link 2 216,632,828 216,664,436 RGD:6480464
G IGFBP4 insulin like growth factor binding protein 4 JBrowse link 17 40,443,450 40,457,725 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL1R1 interleukin 1 receptor type 1 JBrowse link 2 102,069,638 102,179,874 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G INPP5D inositol polyphosphate-5-phosphatase D JBrowse link 2 233,060,342 233,207,903 RGD:6480464
G IQGAP2 IQ motif containing GTPase activating protein 2 JBrowse link 5 76,403,285 76,708,132 RGD:6480464
G IRF9 interferon regulatory factor 9 JBrowse link 14 24,161,265 24,166,565 RGD:6480464
G JUN Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 58,780,791 58,784,047 RGD:6480464
G KLK3 kallikrein related peptidase 3 JBrowse link 19 50,854,915 50,860,764 RGD:6480464
G LITAF lipopolysaccharide induced TNF factor JBrowse link 16 11,547,722 11,636,377 RGD:6480464
G MAP1A microtubule associated protein 1A JBrowse link 15 43,517,608 43,531,611 RGD:6480464
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 JBrowse link 5 56,815,543 56,896,152 RGD:6480464
G MAPK11 mitogen-activated protein kinase 11 JBrowse link 22 50,263,713 50,270,380 RGD:6480464
G MAPK14 mitogen-activated protein kinase 14 JBrowse link 6 36,027,677 36,122,964 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 180,233,143 180,292,083 RGD:6480464
G MGST1 microsomal glutathione S-transferase 1 JBrowse link 12 16,347,142 16,377,192 RGD:6480464
G MMD monocyte to macrophage differentiation associated JBrowse link 17 55,392,617 55,421,886 RGD:6480464
G MMP2 matrix metallopeptidase 2 JBrowse link 16 55,478,830 55,506,691 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NFKB2 nuclear factor kappa B subunit 2 JBrowse link 10 102,394,110 102,402,529 RGD:6480464
G NNAT neuronatin JBrowse link 20 37,521,250 37,523,690 RGD:6480464
G NOP56 NOP56 ribonucleoprotein JBrowse link 20 2,652,632 2,658,393 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NPAS2 neuronal PAS domain protein 2 JBrowse link 2 100,820,139 100,996,829 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G NR1I3 nuclear receptor subfamily 1 group I member 3 JBrowse link 1 161,229,666 161,238,623 RGD:6480464
G PARG poly(ADP-ribose) glycohydrolase JBrowse link 10 49,818,274 49,942,027 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PCNA proliferating cell nuclear antigen JBrowse link 20 5,114,953 5,126,622 RGD:6480464
G PDIA2 protein disulfide isomerase family A member 2 JBrowse link 16 283,164 287,215 RGD:6480464
G PGD phosphogluconate dehydrogenase JBrowse link 1 10,399,064 10,420,511 RGD:6480464
G PLA2G2A phospholipase A2 group IIA JBrowse link 1 19,975,431 19,980,434 RGD:6480464
G PLP2 proteolipid protein 2 JBrowse link X 49,171,898 49,175,235 RGD:6480464
G PML promyelocytic leukemia JBrowse link 15 73,994,673 74,047,827 RGD:6480464
G PPARD peroxisome proliferator activated receptor delta JBrowse link 6 35,342,558 35,428,191 RGD:6480464
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,287,485 12,434,344 RGD:6480464
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,792,021 24,472,905 RGD:6480464
G PRKG1 protein kinase cGMP-dependent 1 JBrowse link 10 50,990,888 52,298,350 RGD:6480464
G PTN pleiotrophin JBrowse link 7 137,227,341 137,343,733 RGD:6480464
G PTPRN2 protein tyrosine phosphatase receptor type N2 JBrowse link 7 157,539,052 158,587,823 RGD:6480464
G RAN RAN, member RAS oncogene family JBrowse link 12 130,871,879 130,877,678 RGD:6480464
G RB1 RB transcriptional corepressor 1 JBrowse link 13 48,303,747 48,481,890 RGD:6480464
G RECK reversion inducing cysteine rich protein with kazal motifs JBrowse link 9 36,036,905 36,124,455 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G RGS5 regulator of G protein signaling 5 JBrowse link 1 163,142,299 163,321,791 RGD:6480464
G SCD stearoyl-CoA desaturase JBrowse link 10 100,347,233 100,364,826 RGD:6480464
G SEPTIN2 septin 2 JBrowse link 2 241,315,187 241,354,027 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G SOD3 superoxide dismutase 3 JBrowse link 4 24,795,478 24,800,845 RGD:6480464
G STAR steroidogenic acute regulatory protein JBrowse link 8 38,142,700 38,150,952 RGD:6480464
G STAT3 signal transducer and activator of transcription 3 JBrowse link 17 42,313,324 42,388,502 RGD:6480464
G TAF1C TATA-box binding protein associated factor, RNA polymerase I subunit C JBrowse link 16 84,177,847 84,187,070 RGD:6480464
G TCF12 transcription factor 12 JBrowse link 15 56,918,090 57,292,595 RGD:6480464
G TERT telomerase reverse transcriptase JBrowse link 5 1,253,148 1,295,068 RGD:6480464
G TFAM transcription factor A, mitochondrial JBrowse link 10 58,385,143 58,399,230 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TNNT2 troponin T2, cardiac type JBrowse link 1 201,359,014 201,377,828 RGD:6480464
G TP53 tumor protein p53 JBrowse link 17 7,668,402 7,687,550 RGD:6480464
G UGP2 UDP-glucose pyrophosphorylase 2 JBrowse link 2 63,840,964 63,891,562 RGD:6480464
G USP4 ubiquitin specific peptidase 4 JBrowse link 3 49,277,144 49,340,053 RGD:6480464
G WARS1 tryptophanyl-tRNA synthetase 1 JBrowse link 14 100,333,789 100,376,327 RGD:6480464
G WEE1 WEE1 G2 checkpoint kinase JBrowse link 11 9,573,670 9,589,985 RGD:6480464
G ZBTB16 zinc finger and BTB domain containing 16 JBrowse link 11 114,059,576 114,256,770 RGD:6480464
G ZMYM2 zinc finger MYM-type containing 2 JBrowse link 13 19,957,406 20,091,848 RGD:6480464
corilagin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAT catalase JBrowse link 11 34,438,934 34,472,060 RGD:6480464
G NR1H4 nuclear receptor subfamily 1 group H member 4 JBrowse link 12 100,473,866 100,564,414 RGD:15042872
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      chemical role 22180
        antioxidant 14685
          ellagic acid 125
            ellagitannin + 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic group 21894
                              organic divalent group 21866
                                organodiyl group 21866
                                  carbonyl group 21838
                                    carbonyl compound 21838
                                      carboxylic acid 20881
                                        aromatic carboxylic acid 11273
                                          benzoic acids 11238
                                            benzoic acid 3718
                                              hydroxybenzoic acid 3010
                                                trihydroxybenzoic acid 2400
                                                  gallic acid 2381
                                                    ellagic acid 125
                                                      ellagitannin + 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.