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ONTOLOGY REPORT - ANNOTATIONS


Term:emedastine
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Accession:CHEBI:4779 term browser browse the term
Definition:1-Methyl-1,4-diazepane in which the hydrogen attached to the nitrogen at position 4 is substituted by a 1-(2-ethoxyethyl)-1H-benzimidazol-2-yl group. A relatively selective histamine H1 antagonist, it is used as the difumatate salt for allergic rhinitis, urticaria, and pruritic skin disorders, and in eyedrops for the symptomatic relief of allergic conjuntivitis.
Synonyms:exact_synonym: 1-(2-ethoxyethyl)-2-(4-methyl-1,4-diazepan-1-yl)-1H-benzimidazole
 related_synonym: 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole;   1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazole;   1-[2-(ethoxy)ethyl]-2-(4-methyl-1-homopiperazinyl)benzimidazole;   Formula=C17H26N4O;   InChI=1S/C17H26N4O/c1-3-22-14-13-21-16-8-5-4-7-15(16)18-17(21)20-10-6-9-19(2)11-12-20/h4-5,7-8H,3,6,9-14H2,1-2H3;   InChIKey=KBUZBQVCBVDWKX-UHFFFAOYSA-N;   SMILES=CCOCCn1c(nc2ccccc12)N1CCCN(C)CC1;   emedastina;   emedastinum
 alt_id: CHEBI:119712
 xref: Beilstein:6068161 "Beilstein";   CAS:87233-61-2 "ChemIDplus";   CAS:87233-61-2 "KEGG COMPOUND";   DrugBank:DB01084;   Drug_Central:999 "DrugCentral";   KEGG:C07785;   KEGG:D07890;   LINCS:LSM-5331
 xref_mesh: MESH:C043345
 xref: Patent:US4430343;   Wikipedia:Emedastine


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emedastine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      application 19353
        pharmaceutical 19222
          drug 19222
            anti-allergic agent 3789
              emedastine 1
                emedastine difumarate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      p-block molecular entity 19637
                        carbon group molecular entity 19528
                          organic molecular entity 19517
                            organic molecule 19436
                              organic cyclic compound 19199
                                organic heterocyclic compound 18276
                                  organic heteropolycyclic compound 17583
                                    organic heterobicyclic compound 16252
                                      benzimidazoles 827
                                        emedastine 1
                                          emedastine difumarate 0
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