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ONTOLOGY REPORT - ANNOTATIONS


Term:enalapril
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Accession:CHEBI:4784 term browser browse the term
Definition:A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).
Synonyms:exact_synonym: N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
 related_synonym: (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline;   (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid;   1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester;   Formula=C20H28N2O5;   InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1;   InChIKey=GBXSMTUPTTWBMN-XIRDDKMYSA-N;   SMILES=CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O;   analapril;   enalaprila;   enalaprilum
 alt_id: CHEBI:116847
 xref: Beilstein:3657467 "Beilstein";   CAS:75847-73-3 "ChemIDplus";   CAS:75847-73-3 "KEGG COMPOUND";   DrugBank:DB00584;   Drug_Central:1005 "DrugCentral";   HMDB:HMDB0014722;   KEGG:C06977;   KEGG:D07892;   LINCS:LSM-3282
 xref_mesh: MESH:D004656
 xref: MetaCyc:CPD0-2065;   PMID:10669559 "ChEMBL";   PMID:23030053 "Europe PMC";   PMID:23413003 "Europe PMC";   Patent:EP12401;   Patent:US4374829;   Wikipedia:Enalapril


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enalapril term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 26 8,148,181 8,209,392 RGD:6480464
G EGR1 early growth response 1 JBrowse link 11 26,046,195 26,049,806 RGD:6480464
G GATA4 GATA binding protein 4 JBrowse link 25 26,126,172 26,211,474 RGD:6480464
G KCND3 potassium voltage-gated channel subfamily D member 3 JBrowse link 17 63,470,829 63,668,354 RGD:6480464
G NAB1 NGFI-A binding protein 1 JBrowse link 37 1,207,619 1,243,546 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 16 15,054,196 15,072,454 RGD:6480464
G NPPA natriuretic peptide A JBrowse link 2 84,406,317 84,408,115 RGD:6480464
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464
G SLC8A1 solute carrier family 8 member A1 JBrowse link 17 32,004,207 32,381,399 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 225
    role 225
      application 191
        pro-agent 15
          prodrug 15
            enalapril 9
              enalapril maleate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 225
    subatomic particle 225
      composite particle 225
        hadron 225
          baryon 225
            nucleon 225
              atomic nucleus 225
                atom 225
                  main group element atom 218
                    p-block element atom 218
                      carbon group element atom 206
                        carbon atom 205
                          organic molecular entity 205
                            organic group 153
                              organic divalent group 152
                                organodiyl group 152
                                  carbonyl group 152
                                    carbonyl compound 152
                                      carboxylic acid 112
                                        carboacyl group 47
                                          univalent carboacyl group 47
                                            carbamoyl group 44
                                              carboxamide 44
                                                peptide 19
                                                  oligopeptide 15
                                                    dipeptide 9
                                                      enalaprilat (anhydrous) 9
                                                        enalapril 9
                                                          enalapril maleate 0
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