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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:photosensitizing agent
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Accession:CHEBI:47868 term browser browse the term
Definition:A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells.
Synonyms:related_synonym: photosensitising agent


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Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        pharmaceutical 19272
          drug 19272
            photosensitizing agent 7686
              5-aminolevulinic acid + 26
              5-aminolevulinic acid hydrochloride 0
              9,10-diphenylanthracene 0
              acetophenone + 5
              benzophenone + 677
              carprofen + 0
              cercosporin 0
              cidofovir anhydrous + 267
              cisplatin 7332
              decarboxytiaprofenic acid 0
              diphenylcyclopropenone 14
              docetaxel anhydrous + 0
              ethyl eosin 0
              gemcitabine + 272
              hematoporphyrin 0
              lomefloxacin + 0
              lomefloxacin hydrochloride 0
              lucanthone + 194
              meso-tetrakis(N-methyl-4-pyridyl)porphine tetrakis(p-toluenesulfonate) 0
              meso-tetrakis(N-methyl-4-pyridyl)porphine(4+) + 1
              methoxsalen + 57
              methyl 5-aminolevulinate + 0
              methyl 5-aminolevulinate hydrochloride 0
              porfimer 0
              porfimer sodium 0
              protoporphyrin + 25
              riboflavin + 30
              safranin O 0
              temoporfin 0
              trioxsalen 3
              verteporfin 24
              vinorelbine + 21
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.