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ONTOLOGY REPORT - ANNOTATIONS


Term:cinacalcet
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Accession:CHEBI:48390 term browser browse the term
Definition:A secondary amino compound that is (1R)-1-(naphthalen-1-yl)ethanamine in which one of the hydrogens attached to the nitrogen is substituted by a 3-[3-(trifluoromethyl)phenyl]propyl group.
Synonyms:exact_synonym: N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine
 related_synonym: (R)-alpha-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine;   CNC;   Formula=C22H22F3N;   InChI=1S/C22H22F3N/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3/t16-/m1/s1;   InChIKey=VDHAWDNDOKGFTD-MRXNPFEDSA-N;   Mimpara;   N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine;   SMILES=C[C@@H](NCCCc1cccc(c1)C(F)(F)F)c1cccc2ccccc12
 xref: CAS:226256-56-0 "ChemIDplus";   DrugBank:DB01012;   Drug_Central:647 "DrugCentral";   KEGG:D03504;   LINCS:LSM-5815
 xref_mesh: MESH:D000069449
 xref: PMID:16680561 "Europe PMC";   PMID:17652181 "Europe PMC";   Patent:US2007060645;   Patent:US6011068;   Patent:US6211244;   Reaxys:10191346 "Reaxys";   Wikipedia:Cinacalcet


show annotations for term's descendants       view all columns           Sort by:
 
cinacalcet term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        pharmaceutical 19214
          drug 19214
            calcimimetic 3
              cinacalcet 3
                cinacalcet carbamate 0
                cinacalcet hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    main group molecular entity 19622
                      s-block molecular entity 19388
                        hydrogen molecular entity 19377
                          hydrides 18283
                            organic hydride 17547
                              organic fundamental parent 17547
                                hydrocarbon 16958
                                  alkane 12514
                                    methane 9394
                                      halomethane 9394
                                        fluoromethanes 6265
                                          fluoroform 6265
                                            trifluoromethyl group 6265
                                              (trifluoromethyl)benzenes 6265
                                                cinacalcet 3
                                                  cinacalcet carbamate 0
                                                  cinacalcet hydrochloride 0
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