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Term:etidronic acid
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Accession:CHEBI:4907 term browser browse the term
Definition:A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
Synonyms:exact_synonym: (1-hydroxyethane-1,1-diyl)bis(phosphonic acid)
 related_synonym: (1-Hydroxyethylene)diphosphonic acid;   (1-Hydroxyethylidene)bis(phosphonic acid);   (1-Hydroxyethylidene)bisphosphonic acid;   (1-Hydroxyethylidene)diphosphonic acid;   (Hydroxyethylidene)diphosphonic acid;   1,1,1-Ethanetriol diphosphonate;   1-Hydroxy-1,1-diphosphonoethane;   1-Hydroxyethane-1,1-bisphosphonic acid;   1-Hydroxyethane-1,1-diphosphonate;   1-Hydroxyethane-1,1-diphosphonic acid;   1-Hydroxyethanediphosphonic acid;   1-Hydroxyethylidene-1,1-bisphosphonate;   1-Hydroxyethylidene-1,1-diphosphonic acid;   Acetodiphosphonic acid;   EHDP;   Ethane-1-hydroxy-1,1-diphosphonate;   Ethane-1-hydroxy-1,1-diphosphonic acid;   Etidronsaeure;   Formula=C2H8O7P2;   HEDP;   Hydroxyethanediphosphonic acid;   InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9);   InChIKey=DBVJJBKOTRCVKF-UHFFFAOYSA-N;   Oxyethylidenediphosphonic acid;   SMILES=CC(O)(P(O)(O)=O)P(O)(O)=O;   acide etidronique;   acido etidronico;   acidum etidronicum;   ethane-1-hydroxy-1,1-bisphosphonic acid;   etidronate
 alt_id: CHEBI:63588
 xref: CAS:2809-21-4 "ChemIDplus";   CAS:2809-21-4 "KEGG COMPOUND";   DrugBank:DB01077;   Drug_Central:1098 "DrugCentral";   HMDB:HMDB0015210;   KEGG:C07736;   KEGG:D02373;   LINCS:LSM-5508
 xref_mesh: MESH:D012968
 xref: PDBeChem:911;   PMID:10385693 "Europe PMC";   PMID:11503828 "Europe PMC";   PMID:17157266 "Europe PMC";   PMID:17214981 "Europe PMC";   PMID:18313802 "Europe PMC";   PMID:18646327 "Europe PMC";   PMID:22515905 "Europe PMC";   PMID:7858370 "Europe PMC";   Patent:US3159581;   Patent:US3400147;   Patent:US3468935;   Patent:US3475486;   Reaxys:1789291 "Reaxys";   Wikipedia:Etidronic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:77356

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etidronic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      chemical role 19189
        ligand 5738
          chelator 5721
            etidronic acid 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      p-block molecular entity 19610
                        pnictogen molecular entity 18514
                          phosphorus molecular entity 9204
                            phosphorus oxoacids and derivatives 9190
                              phosphonic acids 4077
                                1,1-bis(phosphonic acid) 1677
                                  etidronic acid 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.