Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:490877 term browser browse the term
Definition:A purine 2',3'-dideoxyribonucleoside that is inosine in which the hydroxy groups at both the 2' and the 3' positions on the sugar moiety have been replaced by hydrogen. An antiviral drug, it is used as a medication to treat HIV/AIDS.
Synonyms:related_synonym: 2,3-dideoxyinosine;   9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one;   9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one;   9-((2S,5R)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-ol;   9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-1,9-dihydro-6H-purin-6-one;   DDI;   Formula=C10H12N4O3;   InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1;   InChIKey=BXZVVICBKDXVGW-NKWVEPMBSA-N;   SMILES=OC[C@@H]1CC[C@@H](O1)n1cnc2c1nc[nH]c2=O;   ddIno;   didanosina;   didanosinum;   dideoxyinosine
 alt_id: CHEBI:158219;   CHEBI:39738;   CHEBI:4516;   CHEBI:475381;   CHEBI:668806
 xref: Beilstein:3619529 "Beilstein";   CAS:69655-05-6 "ChemIDplus";   CAS:69655-05-6 "KEGG COMPOUND";   DrugBank:DB00900;   Drug_Central:869 "DrugCentral";   KEGG:C06953;   KEGG:D00296;   LINCS:LSM-6017
 xref_mesh: MESH:D016049
 xref: PDBeChem:2DI;   PMID:10386939 "ChEMBL";   PMID:1619614 "ChEMBL";   PMID:17046264 "ChEMBL";   PMID:18549801 "Europe PMC";   PMID:29438107 "Europe PMC";   Patent:EP206497;   Reaxys:3619529 "Reaxys";   Wikipedia:Didanosine

show annotations for term's descendants       view all columns           Sort by:
didanosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Hfe homeostatic iron regulator JBrowse link 17 43,661,276 43,669,327 RGD:6480464
G Mt-co2 mitochondrially encoded cytochrome c oxidase II JBrowse link MT 7,006 7,689 RGD:6480464
G Slc29a3 solute carrier family 29 member 3 JBrowse link 20 30,289,527 30,327,343 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19754
    role 19701
      biological role 19700
        biochemical role 19201
          antimetabolite 8485
            didanosine 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19754
    subatomic particle 19752
      composite particle 19752
        hadron 19752
          baryon 19752
            nucleon 19752
              atomic nucleus 19752
                atom 19752
                  main group element atom 19637
                    p-block element atom 19637
                      carbon group element atom 19528
                        carbon atom 19517
                          organic molecular entity 19517
                            heteroorganic entity 19095
                              organochalcogen compound 18793
                                organooxygen compound 18705
                                  carbohydrates and carbohydrate derivatives 12118
                                    carbohydrate 12118
                                      carbohydrate derivative 11741
                                        glycosyl compound 10799
                                          N-glycosyl compound 5319
                                            nucleoside 5180
                                              deoxyribonucleoside 2706
                                                2',3'-dideoxyribonucleoside 552
                                                  purine 2',3'-dideoxyribonucleoside 6
                                                    didanosine 4
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.