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ONTOLOGY REPORT - ANNOTATIONS


Term:mercaptopurine
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Accession:CHEBI:50667 term browser browse the term
Definition:A member of the class of purines that is 6,7-dihydro-1H-purine carrying a thione group at position 6. An adenine analogue, it is used in the treatment of acute lymphocytic leukemia (ALL), chronic myeloid leukemia (CML), Crohn's disease, and ulcerative colitis.
Synonyms:exact_synonym: 1,7-dihydro-6H-purine-6-thione
 related_synonym: 6-MP;   6-Mercaptopurine;   6-Thiohypoxanthine;   6-Thioxopurine;   Formula=C5H4N4S;   InChI=1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10);   InChIKey=GLVAUDGFNGKCSF-UHFFFAOYSA-N;   Mercaptopurina;   Mercapurin;   Puri-Nethol;   Purinethol;   SMILES=S=c1[nH]cnc2nc[nH]c12;   mercaptopurinum
 xref: Beilstein:132916 "Beilstein";   CAS:50-44-2 "ChemIDplus";   CAS:50-44-2 "KEGG COMPOUND";   DrugBank:DB01033;   KEGG:C02380;   KEGG:D04931
 xref_mesh: MESH:D015122
 xref: PDBeChem:PM6;   PMID:16267626 "Europe PMC";   PMID:28011186 "Europe PMC";   PMID:28166217 "Europe PMC";   PMID:28212467 "Europe PMC";   PMID:28295989 "Europe PMC";   PMID:28301625 "Europe PMC";   PMID:28406092 "Europe PMC";   PMID:28418010 "Europe PMC";   PMID:28484608 "Europe PMC";   PMID:28574837 "Europe PMC";   Patent:US2697709;   Patent:US2721866;   Reaxys:132916 "Reaxys"
 cyclic_relationship: is_tautomer_of CHEBI:2208


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  CHEBI ontology 0
    role 0
      biological role 0
        biochemical role 0
          antimetabolite 0
            mercaptopurine 0
              mercaptopurine hydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    subatomic particle 0
      composite particle 0
        hadron 0
          baryon 0
            nucleon 0
              atomic nucleus 0
                atom 0
                  main group element atom 0
                    p-block element atom 0
                      carbon group element atom 0
                        carbon atom 0
                          organic molecular entity 0
                            organic molecule 0
                              organic cyclic compound 0
                                organic heterocyclic compound 0
                                  organic heteropolycyclic compound 0
                                    organic heterobicyclic compound 0
                                      imidazopyrimidine 0
                                        purines 0
                                          mercaptopurine 0
                                            mercaptopurine hydrate 0
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