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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor
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Accession:CHEBI:50696 term browser browse the term
Definition:An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129).
Synonyms:related_synonym: EC 2.4.1.129 inhibitor;   EC 2.4.1.129 inhibitors;   PBP3 inhibitor;   PG-II inhibitor;   PG-II inhibitors;   [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitor;   [poly-N-acetyl-D-glucosaminyl-(1->4)-(N-acetyl-D-muramoylpentapeptide)]-diphosphoundecaprenol:[N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide]-diphosphoundecaprenol disaccharidetransferase inhibitors;   bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitor;   bactoprenyldiphospho-N-acetylmuramoyl-(N-acetyl-D-glucosaminyl)-pentapeptide:peptidoglycan N-acetylmuramoyl-N-acetyl-D-glucosaminyltransferase inhibitors;   penicillin binding protein 1B inhibitor;   penicillin binding protein 1B inhibitors;   penicillin binding protein 3 inhibitor;   penicillin binding protein 3 inhibitors;   peptidoglycan glycosyltransferase (EC 2.4.1.129) inhibitors;   peptidoglycan glycosyltransferase inhibitor;   peptidoglycan glycosyltransferase inhibitors;   peptidoglycan transglycosylase inhibitor;   peptidoglycan transglycosylase inhibitors;   undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitor;   undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide):undecaprenyldiphospho-(N-acetyl-D-glucosaminyl-(1->4)-N-acetyl-D-muramoylpentapeptide) disaccharidetransferase inhibitors


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aztreonam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 6 7,935,771 7,961,207 RGD:6480464
G Abcg8 ATP binding cassette subfamily G member 8 JBrowse link 6 7,961,413 7,980,708 RGD:6480464
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 JBrowse link 14 86,345,946 86,560,694 RGD:6480464
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 JBrowse link 13 53,750,470 53,870,288 RGD:6480464
G RT1-Ha RT1 class II, locus Ha JBrowse link 20 3,875,478 3,885,140 RGD:6480464
G Slc10a1 solute carrier family 10 member 1 JBrowse link 6 104,617,730 104,631,355 RGD:6480464
G Slc10a2 solute carrier family 10 member 2 JBrowse link 16 90,324,420 90,350,254 RGD:6480464
G Slc51b solute carrier family 51 subunit beta JBrowse link 8 70,930,196 70,938,559 RGD:6480464
ceftazidime pentahydrate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc4 ATP binding cassette subfamily C member 4 JBrowse link 15 103,695,415 103,927,980 RGD:6480464
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      biological role 19734
        biochemical role 19227
          enzyme inhibitor 18102
            EC 2.* (transferase) inhibitor 13550
              EC 2.4.* (glycosyltransferase) inhibitor 343
                EC 2.4.1.* (hexosyltransferase) inhibitor 141
                  EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor 12
                    aztreonam + 9
                    ceftazidime + 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.