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ONTOLOGY REPORT - ANNOTATIONS


Term:antiparathyroid drug
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Accession:CHEBI:50827 term browser browse the term
Definition:A drug used to treat hyperparathyroidism by reducing the excessive production of parathyroid hormones.
Synonyms:related_synonym: antiparathyroid agent;   antiparathyroid agents;   antiparathyroid drugs


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paricalcitol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AADAC arylacetamide deacetylase JBrowse link 3 151,814,008 151,828,488 RGD:6480464
G ADIPOQ adiponectin, C1Q and collagen domain containing JBrowse link 3 186,842,710 186,858,463 RGD:6480464
G ADIPOR1 adiponectin receptor 1 JBrowse link 1 202,940,825 202,958,572 RGD:6480464
G ALPL alkaline phosphatase, biomineralization associated JBrowse link 1 21,508,984 21,578,412 RGD:6480464
G APOE apolipoprotein E JBrowse link 19 44,905,796 44,909,395 RGD:6480464
G B4GALT1 beta-1,4-galactosyltransferase 1 JBrowse link 9 33,110,641 33,167,358 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BCL2L1 BCL2 like 1 JBrowse link 20 31,664,452 31,723,963 RGD:6480464
G BMP4 bone morphogenetic protein 4 JBrowse link 14 53,949,736 53,956,891 RGD:6480464
G CAMP cathelicidin antimicrobial peptide JBrowse link 3 48,223,495 48,225,485 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CCR2 C-C motif chemokine receptor 2 JBrowse link 3 46,353,744 46,360,940 RGD:6480464
G CD14 CD14 molecule JBrowse link 5 140,631,728 140,633,701 RGD:6480464
G CES1 carboxylesterase 1 JBrowse link 16 55,802,851 55,833,127 RGD:6480464
G COL15A1 collagen type XV alpha 1 chain JBrowse link 9 98,943,392 99,070,787 RGD:6480464
G COL1A1 collagen type I alpha 1 chain JBrowse link 17 50,184,096 50,201,649 RGD:6480464
G COL3A1 collagen type III alpha 1 chain JBrowse link 2 188,974,373 189,012,746 RGD:6480464
G CP ceruloplasmin JBrowse link 3 149,162,410 149,222,008 RGD:6480464
G CPN2 carboxypeptidase N subunit 2 JBrowse link 3 194,339,765 194,351,387 RGD:6480464
G CPT1A carnitine palmitoyltransferase 1A JBrowse link 11 68,754,620 68,844,410 RGD:6480464
G CRIP1 cysteine rich protein 1 JBrowse link 14 105,486,886 105,488,947 RGD:6480464
G CTDSPL CTD small phosphatase like JBrowse link 3 37,861,880 37,984,469 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G CYBA cytochrome b-245 alpha chain JBrowse link 16 88,643,289 88,651,079 RGD:6480464
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 JBrowse link 2 38,067,603 38,076,181 RGD:6480464
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 JBrowse link 20 54,145,731 54,174,032 RGD:6480464
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 JBrowse link 19 40,991,282 41,018,398 RGD:6480464
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 JBrowse link 7 99,756,967 99,784,184 RGD:6480464
G EDN1 endothelin 1 JBrowse link 6 12,256,463 12,297,194 RGD:6480464
G EDNRB endothelin receptor type B JBrowse link 13 77,895,481 77,975,527 RGD:6480464
G ENG endoglin JBrowse link 9 127,815,012 127,854,773 RGD:6480464
G FBLN2 fibulin 2 JBrowse link 3 13,549,125 13,638,408 RGD:6480464
G ICAM1 intercellular adhesion molecule 1 JBrowse link 19 10,271,120 10,286,615 RGD:6480464
G ID3 inhibitor of DNA binding 3, HLH protein JBrowse link 1 23,557,926 23,559,501 RGD:6480464
G IL11 interleukin 11 JBrowse link 19 55,364,382 55,370,463 RGD:6480464
G IL1A interleukin 1 alpha JBrowse link 2 112,773,925 112,784,493 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL1RN interleukin 1 receptor antagonist JBrowse link 2 113,099,365 113,134,016 RGD:6480464
G IL24 interleukin 24 JBrowse link 1 206,897,404 206,904,139 RGD:6480464
G IL36RN interleukin 36 receptor antagonist JBrowse link 2 113,058,638 113,064,744 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G ITGA2 integrin subunit alpha 2 JBrowse link 5 52,989,352 53,094,779 RGD:6480464
G ITGAM integrin subunit alpha M JBrowse link 16 31,259,975 31,332,877 RGD:6480464
G MAPK13 mitogen-activated protein kinase 13 JBrowse link 6 36,130,513 36,144,521 RGD:6480464
G MELTF melanotransferrin JBrowse link 3 197,001,740 197,029,817 RGD:6480464
G MGP matrix Gla protein JBrowse link 12 14,880,864 14,885,854 RGD:6480464
G MRPL33 mitochondrial ribosomal protein L33 JBrowse link 2 27,771,717 27,779,741 RGD:6480464
G NCOR1 nuclear receptor corepressor 1 JBrowse link 17 16,029,157 16,216,475 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NOS3 nitric oxide synthase 3 JBrowse link 7 150,991,017 151,014,588 RGD:6480464
G NPPA natriuretic peptide A JBrowse link 1 11,845,709 11,847,783 RGD:6480464
G NPY neuropeptide Y JBrowse link 7 24,284,190 24,291,862 RGD:6480464
G NR4A1 nuclear receptor subfamily 4 group A member 1 JBrowse link 12 52,022,832 52,059,507 RGD:6480464
G NR4A2 nuclear receptor subfamily 4 group A member 2 JBrowse link 2 156,324,432 156,332,724 RGD:6480464
G PEX11A peroxisomal biogenesis factor 11 alpha JBrowse link 15 89,681,535 89,690,754 RGD:6480464
G POSTN periostin JBrowse link 13 37,562,582 37,598,844 RGD:6480464
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,287,485 12,434,344 RGD:6480464
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 JBrowse link 5 40,759,379 40,798,195 RGD:6480464
G PRKCA protein kinase C alpha JBrowse link 17 66,302,613 66,810,743 RGD:6480464
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 122,369,906 122,395,703 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 186,671,791 186,680,423 RGD:6480464
G PTH parathyroid hormone JBrowse link 11 13,492,045 13,496,175 RGD:6480464
G RARRES1 retinoic acid receptor responder 1 JBrowse link 3 158,696,892 158,732,944 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G REN renin JBrowse link 1 204,154,819 204,166,337 RGD:6480464
G SELL selectin L JBrowse link 1 169,690,667 169,711,620 RGD:6480464
G SERPINE1 serpin family E member 1 JBrowse link 7 101,127,104 101,139,247 RGD:6480464
G SMAD2 SMAD family member 2 JBrowse link 18 47,808,957 47,931,188 RGD:6480464
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,693 31,668,931 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G SOD3 superoxide dismutase 3 JBrowse link 4 24,795,478 24,800,845 RGD:6480464
G SPP1 secreted phosphoprotein 1 JBrowse link 4 87,975,650 87,983,411 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TGFB3 transforming growth factor beta 3 JBrowse link 14 75,958,061 75,983,011 RGD:6480464
G THBD thrombomodulin JBrowse link 20 23,045,633 23,049,672 RGD:6480464
G THBS1 thrombospondin 1 JBrowse link 15 39,581,079 39,599,466 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TNFRSF11B TNF receptor superfamily member 11b JBrowse link 8 118,923,557 118,951,885 RGD:6480464
G TNFSF11 TNF superfamily member 11 JBrowse link 13 42,562,736 42,608,013 RGD:6480464
G TNXB tenascin XB JBrowse link 6 32,041,153 32,109,338 RGD:6480464
G TREM1 triggering receptor expressed on myeloid cells 1 JBrowse link 6 41,267,385 41,286,745 RGD:6480464
G VDR vitamin D receptor JBrowse link 12 47,841,537 47,905,022 RGD:6480464
G VWF von Willebrand factor JBrowse link 12 5,948,874 6,124,675 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      biological role 23606
        pharmacological role 20965
          antagonist 17220
            hormone antagonist 11033
              antiparathyroid drug 83
                paricalcitol 83
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      application 23035
        pharmaceutical 22583
          drug 22583
            receptor modulator 19641
              hormone receptor modulator 19527
                hormone antagonist 11033
                  antiparathyroid drug 83
                    paricalcitol 83
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.