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ONTOLOGY REPORT - ANNOTATIONS


Term:ciprofibrate
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Accession:CHEBI:50867 term browser browse the term
Definition:A cyclopropane that has formula C13H14Cl2O3.
Synonyms:exact_synonym: 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
 related_synonym: Formula=C13H14Cl2O3;   InChI=1S/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17);   InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N;   SMILES=CC(C)(Oc1ccc(cc1)C1CC1(Cl)Cl)C(O)=O;   ciprofibrato;   ciprofibratum
 xref: Beilstein:1984981 "ChemIDplus";   CAS:52214-84-3 "ChemIDplus";   Drug_Central:658 "DrugCentral";   KEGG:D03521;   LINCS:LSM-1600
 xref_mesh: MESH:C019304
 xref: Patent:DE2343606;   Patent:US3948973;   Reaxys:1984981 "Reaxys";   Wikipedia:Ciprofibrate


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ciprofibrate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:6480464
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Abcc3 ATP binding cassette subfamily C member 3 JBrowse link 10 82,047,308 82,116,928 RGD:6480464
G Acaa1a acetyl-CoA acyltransferase 1A JBrowse link 8 128,027,880 128,036,471 RGD:6480464
G Acaa2 acetyl-CoA acyltransferase 2 JBrowse link 18 70,733,872 70,762,395 RGD:6480464
G Acot1 acyl-CoA thioesterase 1 JBrowse link 6 107,485,088 107,493,082 RGD:6480464
G Acot2 acyl-CoA thioesterase 2 JBrowse link 6 107,460,596 107,468,324 RGD:6480464
G Acot3 acyl-CoA thioesterase 3 JBrowse link 6 107,531,508 107,537,446 RGD:6480464
G Acot4 acyl-CoA thioesterase 4 JBrowse link 6 107,517,668 107,522,952 RGD:6480464
G Acox1 acyl-CoA oxidase 1 JBrowse link 10 104,724,534 104,748,003 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:6480464
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 JBrowse link 11 25,342,119 25,350,938 RGD:6480464
G Aig1 androgen-induced 1 JBrowse link 1 7,816,841 8,038,805 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 JBrowse link 10 47,525,486 47,546,535 RGD:6480464
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 JBrowse link 13 85,580,828 85,597,497 RGD:6480464
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:6480464
G Apcs amyloid P component, serum JBrowse link 13 91,426,621 91,427,417 RGD:6480464
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:6480464
G Asgr1 asialoglycoprotein receptor 1 JBrowse link 10 56,662,188 56,666,086 RGD:6480464
G Baat bile acid CoA:amino acid N-acyltransferase JBrowse link 5 64,768,397 64,777,368 RGD:6480464
G Bdh1 3-hydroxybutyrate dehydrogenase 1 JBrowse link 11 72,577,547 72,619,435 RGD:6480464
G C9 complement C9 JBrowse link 2 55,775,562 55,823,807 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cbr1 carbonyl reductase 1 JBrowse link 11 33,813,041 33,815,418 RGD:6480464
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:6480464
G Cd14 CD14 molecule JBrowse link 18 29,560,341 29,562,290 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cd63 Cd63 molecule JBrowse link 7 3,320,250 3,335,583 RGD:6480464
G Col4a2 collagen type IV alpha 2 chain JBrowse link 16 83,386,388 83,522,169 RGD:6480464
G Cpt1b carnitine palmitoyltransferase 1B JBrowse link 7 130,395,211 130,404,731 RGD:6480464
G Cpt2 carnitine palmitoyltransferase 2 JBrowse link 5 127,505,646 127,523,016 RGD:6480464
G Crat carnitine O-acetyltransferase JBrowse link 3 8,967,984 8,981,959 RGD:6480464
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:6480464
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:6480464
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 JBrowse link 1 256,382,861 256,386,729 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 JBrowse link 1 83,103,925 83,119,578 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 JBrowse link 12 11,053,888 11,082,742 RGD:6480464
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 JBrowse link 5 134,492,734 134,507,158 RGD:6480464
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 JBrowse link 7 15,179,472 15,191,113 RGD:6480464
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 JBrowse link 2 102,701,903 102,871,257 RGD:6480464
G Dpp4 dipeptidylpeptidase 4 JBrowse link 3 48,291,055 48,372,672 RGD:6480464
G Ech1 enoyl-CoA hydratase 1 JBrowse link 1 87,009,798 87,015,996 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase JBrowse link 11 82,945,104 82,978,364 RGD:6480464
G Elovl3 ELOVL fatty acid elongase 3 JBrowse link 1 265,883,353 265,887,181 RGD:6480464
G Ets2 ETS proto-oncogene 2, transcription factor JBrowse link 11 36,075,709 36,092,495 RGD:6480464
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:6480464
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gjb1 gap junction protein, beta 1 JBrowse link X 71,272,030 71,279,973 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:6480464
G Gsta2 glutathione S-transferase alpha 2 JBrowse link 8 85,640,081 85,645,621 RGD:6480464
G Gstk1 glutathione S-transferase kappa 1 JBrowse link 4 71,621,777 71,626,096 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:6480464
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta JBrowse link 6 27,555,408 27,589,539 RGD:6480464
G Hdac1 histone deacetylase 1 JBrowse link 5 147,716,664 147,743,723 RGD:6480464
G Hgf hepatocyte growth factor JBrowse link 4 15,435,460 15,505,377 RGD:6480464
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 JBrowse link 2 200,452,623 200,480,785 RGD:6480464
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 JBrowse link 14 7,054,724 7,104,567 RGD:6480464
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 JBrowse link 18 44,810,462 44,897,677 RGD:6480464
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 JBrowse link 2 200,756,557 200,762,492 RGD:6480464
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:6480464
G Igfbp2 insulin-like growth factor binding protein 2 JBrowse link 9 80,118,029 80,144,804 RGD:6480464
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1rap interleukin 1 receptor accessory protein JBrowse link 11 77,456,648 77,593,208 RGD:6480464
G Impact impact RWD domain protein JBrowse link 18 4,325,872 4,346,734 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Itln1 intelectin 1 JBrowse link 13 89,919,570 89,929,774 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Junb JunB proto-oncogene, AP-1 transcription factor subunit JBrowse link 19 26,092,972 26,094,756 RGD:6480464
G Krt8 keratin 8 JBrowse link 7 143,596,511 143,603,745 RGD:6480464
G Lcn2 lipocalin 2 JBrowse link 3 11,414,189 11,417,534 RGD:6480464
G Lgals3bp galectin 3 binding protein JBrowse link 10 107,415,334 107,424,672 RGD:6480464
G Lpcat3 lysophosphatidylcholine acyltransferase 3 JBrowse link 4 157,181,722 157,222,997 RGD:6480464
G Lpl lipoprotein lipase JBrowse link 16 22,537,687 22,561,487 RGD:6480464
G Ly6d lymphocyte antigen 6 family member D JBrowse link 7 115,993,304 115,994,812 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:6480464
G Myh1 myosin heavy chain 1 JBrowse link 10 53,740,841 53,764,610 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Oat ornithine aminotransferase JBrowse link 1 204,562,289 204,582,070 RGD:6480464
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:6480464
G Palmd palmdelphin JBrowse link 2 220,481,292 220,536,004 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:6480464
G Pex11a peroxisomal biogenesis factor 11 alpha JBrowse link 1 141,474,189 141,481,270 RGD:6480464
G Phlda1 pleckstrin homology-like domain, family A, member 1 JBrowse link 7 54,247,460 54,249,664 RGD:6480464
G Plin2 perilipin 2 JBrowse link 5 104,984,413 105,010,863 RGD:6480464
G Plscr1 phospholipid scramblase 1 JBrowse link 8 99,625,523 99,645,882 RGD:6480464
G Pon1 paraoxonase 1 JBrowse link 4 30,249,749 30,276,297 RGD:6480464
G Pon2 paraoxonase 2 JBrowse link 4 30,344,705 30,380,119 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rbm3 RNA binding motif protein 3 JBrowse link X 15,098,880 15,102,344 RGD:6480464
G Retsat retinol saturase JBrowse link 4 100,465,365 100,474,128 RGD:6480464
G Rpl12 ribosomal protein L12 JBrowse link 3 12,009,578 12,011,952 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Slc10a1 solute carrier family 10 member 1 JBrowse link 6 104,617,730 104,631,355 RGD:6480464
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
G Slc25a34 solute carrier family 25, member 34 JBrowse link 5 160,175,206 160,179,978 RGD:6480464
G Slc37a4 solute carrier family 37 member 4 JBrowse link 8 48,716,914 48,723,024 RGD:6480464
G Slc4a4 solute carrier family 4 member 4 JBrowse link 14 20,476,258 20,817,042 RGD:6480464
G Slco1b2 solute carrier organic anion transporter family member 1B2 JBrowse link 4 175,814,118 175,881,775 RGD:6480464
G Slco2a1 solute carrier organic anion transporter family, member 2a1 JBrowse link 8 111,495,443 111,577,320 RGD:6480464
G Slco2b1 solute carrier organic anion transporter family, member 2b1 JBrowse link 1 164,623,313 164,671,612 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Stat5b signal transducer and activator of transcription 5B JBrowse link 10 88,686,207 88,712,313 RGD:6480464
G Sult2a1 sulfotransferase family 2A member 1 JBrowse link 1 76,558,721 76,614,315 RGD:6480464
G Tagln2 transgelin 2 JBrowse link 13 90,807,196 90,814,119 RGD:6480464
G Tm4sf4 transmembrane 4 L six family member 4 JBrowse link 2 147,532,032 147,547,254 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 JBrowse link 10 48,903,540 48,925,036 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 14 22,724,399 22,736,148 RGD:6480464
G Vnn3 vanin 3 JBrowse link 1 22,649,114 22,661,376 RGD:6480464

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  CHEBI ontology 19728
    role 19675
      application 19328
        pharmaceutical 19202
          drug 19202
            antilipemic drug 6369
              ciprofibrate 138
Path 2
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  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        monocarboxylic acid 17264
                                          ciprofibrate 138
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.