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ONTOLOGY REPORT - ANNOTATIONS


Term:genotoxin
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Accession:CHEBI:50902 term browser browse the term
Definition:A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
Synonyms:related_synonym: genotoxic agent;   genotoxic agents;   genotoxins
 xref: Wikipedia:Genotoxicity


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  CHEBI ontology 23699
    role 23588
      biological role 23549
        aetiopathogenetic role 22200
          genotoxin 17265
            1,5-dinitronaphthalene 0
            1-naphthol + 169
            2,6-dinitrotoluene 2184
            2-naphthol + 33
            4-methoxyestrone + 0
            7-epi-cylindrospermopsin 0
            MeIQx + 170
            N-(2,6-diethylphenyl)-2-chloroacetamide 1
            N-ethyl-N-nitrosourea 514
            N-hydroxy-MeIQx 0
            N-hydroxy-PhIP 26
            acridine + 27
            arsenic trichloride 40
            benzamidoxime 6
            benzo[a]pyrene-7,8-dione 20
            beryllium dichloride 3
            cadmium nitrate + 3
            cadmium nitrate tetrahydrate 0
            camptothecin 200
            catechol + 309
            cisplatin 8004
            cobalt(2+) sulfate heptahydrate 0
            cylindrospermopsin 558
            ebselen 53
            ethoxyquin 39
            ethyl methanesulfonate 2319
            hydrogen peroxide + 3185
            hydrogen sulfide + 2003
            hydroxyurea 219
            imidacloprid + 78
            methyl methanesulfonate 3882
            mutagen + 16805
            o-anisidine 98
            p-anisidine + 38
            parathion-methyl 47
            riddelliine + 57
            riddelliine N-oxide 0
            tolylfluanid 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.