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ONTOLOGY REPORT - ANNOTATIONS


Term:genotoxin
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Accession:CHEBI:50902 term browser browse the term
Definition:A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
Synonyms:related_synonym: genotoxic agent;   genotoxic agents;   genotoxins
 xref: Wikipedia:Genotoxicity


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  CHEBI ontology 20742
    role 20720
      biological role 20719
        aetiopathogenetic role 19749
          genotoxin 16554
            1,5-dinitronaphthalene 0
            1-naphthol + 164
            2,6-dinitrotoluene 2178
            2-naphthol + 35
            4-methoxyestrone + 0
            7-epi-cylindrospermopsin 0
            MeIQx + 163
            N-(2,6-diethylphenyl)-2-chloroacetamide 1
            N-ethyl-N-nitrosourea 544
            N-hydroxy-MeIQx 0
            N-hydroxy-PhIP 21
            acridine + 27
            arsenic trichloride 40
            benzamidoxime 6
            benzo[a]pyrene-7,8-dione 17
            beryllium dichloride 3
            cadmium nitrate + 3
            cadmium nitrate tetrahydrate 0
            camptothecin 196
            catechol + 298
            cisplatin 7394
            cobalt(2+) sulfate heptahydrate 0
            cylindrospermopsin 524
            ebselen 53
            ethoxyquin 45
            ethyl methanesulfonate 2191
            hydrogen peroxide + 3062
            hydrogen sulfide + 2015
            hydroxyurea 222
            imidacloprid + 77
            methyl methanesulfonate 3674
            mutagen + 16158
            o-anisidine 97
            p-anisidine + 43
            parathion-methyl 48
            riddelliine + 57
            riddelliine N-oxide 0
            tolylfluanid 8
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.