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ONTOLOGY REPORT - ANNOTATIONS


Term:teratogenic agent
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Accession:CHEBI:50905 term browser browse the term
Definition:A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect.
Synonyms:related_synonym: agent teratogene;   teratogen;   teratogeno


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acetylsalicylic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G PTGS1 prostaglandin-endoperoxide synthase 1 JBrowse link 9 60,195,118 60,216,847 RGD:6480464
amlodipine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464
benazepril term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DES desmin JBrowse link 37 25,933,525 25,939,910 RGD:6480464
cilazapril monohydrate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AGT angiotensinogen JBrowse link 4 8,681,192 8,694,059 RGD:6480464
G REN renin JBrowse link 38 744,540 766,998 RGD:6480464
clofibrate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACAA2 acetyl-CoA acyltransferase 2 JBrowse link 7 79,028,636 79,057,720 RGD:6480464
G ACADVL acyl-CoA dehydrogenase very long chain JBrowse link 5 32,189,191 32,194,255 RGD:6480464
G AHCY adenosylhomocysteinase JBrowse link 24 23,410,553 23,423,494 RGD:6480464
G ASL argininosuccinate lyase JBrowse link 6 768,522 779,144 RGD:6480464
G ASS1 argininosuccinate synthase 1 JBrowse link 9 53,425,228 53,478,007 RGD:6480464
G CPS1 carbamoyl-phosphate synthase 1 JBrowse link 37 18,308,164 18,428,487 RGD:6480464
G CPT2 carnitine palmitoyltransferase 2 JBrowse link 5 55,718,209 55,786,175 RGD:6480464
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 JBrowse link 30 37,818,400 37,824,192 RGD:6480464
G CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 JBrowse link 1 112,932,246 112,938,248 RGD:6480464
G CYP2B6 cytochrome P450 2B11 JBrowse link 1 112,817,561 112,833,294 RGD:6480464
G CYP2C18 cytochrome P450 2C21 JBrowse link 28 8,727,010 8,750,427 RGD:6480464
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 JBrowse link 28 41,079,164 41,089,188 RGD:6480464
G CYP3A12 cytochrome P-450 3A12 RGD:6480464
G CYP3A26 cytochrome P450 3A26 JBrowse link 6 9,777,663 9,815,345 RGD:6480464
G CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 JBrowse link 15 13,663,337 13,676,350 RGD:6480464
G DLST dihydrolipoamide S-succinyltransferase JBrowse link 8 48,003,730 48,025,001 RGD:6480464
G ECHS1 enoyl-CoA hydratase, short chain 1 JBrowse link 28 40,939,856 40,947,694 RGD:6480464
G GDI1 GDP dissociation inhibitor 1 JBrowse link X 122,141,633 122,146,724 RGD:6480464
G GSTA4 glutathione S-transferase alpha 4 JBrowse link 12 20,426,724 20,443,200 RGD:6480464
G GSTK1 glutathione S-transferase kappa 1 JBrowse link 16 6,411,678 6,416,135 RGD:6480464
G GSTO1 glutathione S-transferase omega 1 JBrowse link 28 16,569,421 16,579,239 RGD:6480464
G HADH hydroxyacyl-CoA dehydrogenase JBrowse link 32 28,460,445 28,506,141 RGD:6480464
G HSPD1 heat shock protein family D (Hsp60) member 1 JBrowse link 37 7,010,421 7,025,912 RGD:6480464
G KRT1 keratin 1 JBrowse link 27 2,422,150 2,427,160 RGD:6480464
G KRT18 keratin 18 JBrowse link 27 2,189,269 2,193,368 RGD:6480464
G LOC100855679 serine--pyruvate aminotransferase, mitochondrial JBrowse link 25 50,968,291 50,976,089 RGD:6480464
G LOC474938 glutathione S-transferase A2 JBrowse link 12 20,349,133 20,365,023 RGD:6480464
G LOC479912 glutathione S-transferase Mu 1 JBrowse link 6 42,201,697 42,207,886 RGD:6480464
G MGST1 microsomal glutathione S-transferase 1 JBrowse link 27 30,370,588 30,391,898 RGD:6480464
G PC pyruvate carboxylase JBrowse link 18 50,406,994 50,507,677 RGD:6480464
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial JBrowse link 8 4,099,016 4,107,870 RGD:6480464
G PRDX6 peroxiredoxin 6 JBrowse link 7 25,663,238 25,675,855 RGD:6480464
G SELENBP1 selenium binding protein 1 JBrowse link 17 60,410,727 60,418,770 RGD:6480464
G SHMT1 serine hydroxymethyltransferase 1 JBrowse link 5 41,221,531 41,248,653 RGD:6480464
G UGP2 UDP-glucose pyrophosphorylase 2 JBrowse link 10 63,532,366 63,598,362 RGD:6480464
G UQCRC1 ubiquinol-cytochrome c reductase core protein 1 JBrowse link 20 40,507,767 40,515,854 RGD:6480464
G UROC1 urocanate hydratase 1 JBrowse link 20 676,624 717,109 RGD:6480464
felodipine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 33 23,444,367 23,456,405 RGD:6480464
valproic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G DHRS4 dehydrogenase/reductase 4 JBrowse link 8 4,046,532 4,058,498 RGD:6480464

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 227
    role 227
      biological role 227
        aetiopathogenetic role 145
          teratogenic agent 43
            (S)-nicotine + 0
            (S)-thalidomide + 0
            1,1-dimethylhydrazine 0
            2-(2-methoxyethoxy)ethanol 0
            2-amino-6-hydroxyaminopurine 0
            2-ethoxyethanol + 0
            6-aminonicotinamide 0
            BMS-453 0
            Evans blue 0
            Evans blue free acid 0
            N(6)-hydroxyadenine 0
            N-methyl-N-nitrosourea 0
            acetaldehyde + 0
            acetylsalicylic acid + 1
            ammodendrine 0
            anabasine + 0
            arotinoid acid 0
            azetidine-2-carboxylic acid + 0
            busulfan 0
            dibutyl phthalate 0
            diethyl phthalate 0
            diisobutyl phthalate 0
            dinocap 0
            ethanol + 41
            ethyl methanesulfonate 0
            flubendazole 0
            flumioxazin 0
            flumipropyn 0
            hadacidin 0
            hydroxyurea 0
            isotretinoin 0
            malachite green 0
            mevinolinic acid 0
            nicotine + 0
            ochratoxin A + 0
            phenytoin 0
            solasodine 0
            soraphen A 0
            tazarotene 0
            tazarotenic acid + 0
            thalidomide + 0
            valproic acid + 1
            valpromide 0
            vismodegib 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.