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ONTOLOGY REPORT - ANNOTATIONS


Term:flucloxacillin
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Accession:CHEBI:5098 term browser browse the term
Definition:A penicillin compound having a 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido] side-chain.
Synonyms:exact_synonym: 6beta-[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido]-2,2-dimethylpenam-3alpha-carboxylic acid
 related_synonym: (2S,5R,6R)-6-({[3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;   3-(2-Chloro-6-fluorophenyl)-5-methyl-4-isoxazolylpenicillin;   Floxacillin;   Floxapen;   Formula=C19H17ClFN3O5S;   InChI=1S/C19H17ClFN3O5S/c1-7-10(12(23-29-7)11-8(20)5-4-6-9(11)21)15(25)22-13-16(26)24-14(18(27)28)19(2,3)30-17(13)24/h4-6,13-14,17H,1-3H3,(H,22,25)(H,27,28)/t13-,14+,17-/m1/s1;   InChIKey=UIOFUWFRIANQPC-JKIFEVAISA-N;   SMILES=[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)c1c(C)onc1-c1c(F)cccc1Cl)C(O)=O;   flucloxacilina;   flucloxacilline;   flucloxacillinum
 xref: Beilstein:4771988 "Beilstein";   CAS:5250-39-5 "ChemIDplus";   CAS:5250-39-5 "KEGG COMPOUND";   DrugBank:DB00301;   Drug_Central:1183 "DrugCentral";   KEGG:C11748;   KEGG:D04196
 xref_mesh: MESH:D005436
 xref: PMID:12569987 "Europe PMC";   PMID:15773973 "Europe PMC";   PMID:23032409 "Europe PMC";   PMID:23542420 "Europe PMC";   PMID:25998949 "Europe PMC";   PMID:29017833 "Europe PMC";   PMID:5481218 "Europe PMC";   Reaxys:4771988 "Reaxys";   Wikipedia:Flucloxacillin
 cyclic_relationship: is_conjugate_acid_of CHEBI:52037


show annotations for term's descendants       view all columns           Sort by:
 
flucloxacillin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Akr1b10 aldo-keto reductase family 1 member B10 JBrowse link 4 61,813,265 61,830,371 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd69 Cd69 molecule JBrowse link 4 163,041,147 163,049,065 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 C-X-C motif chemokine ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:6480464
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Rorc RAR-related orphan receptor C JBrowse link 2 195,612,471 195,636,797 RGD:6480464
G S100a8 S100 calcium binding protein A8 JBrowse link 2 190,073,239 190,074,333 RGD:6480464
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:6480464
G Srxn1 sulfiredoxin 1 JBrowse link 3 147,608,850 147,614,410 RGD:6480464
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        aetiopathogenetic role 18793
          allergen 16859
            penicillin 259
              flucloxacillin 23
                flucloxacilloyl group + 0
                flucloxacilloyl-L-lysine + 0
                flucloxcillanyl group 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                lactam 7679
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      penams 259
                                                        penicillanic acids 259
                                                          penicillanic acid 259
                                                            6-aminopenicillanic acid 259
                                                              penicillin 259
                                                                penicillin allergen 256
                                                                  flucloxacillin 23
                                                                    flucloxacilloyl group + 0
                                                                    flucloxacilloyl-L-lysine + 0
                                                                    flucloxcillanyl group 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.