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ONTOLOGY REPORT - ANNOTATIONS


Term:flucytosine
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Accession:CHEBI:5100 term browser browse the term
Definition:An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.
Synonyms:exact_synonym: 4-amino-5-fluoropyrimidin-2(1H)-one
 related_synonym: 5-FC;   5-Fluorocystosine;   5-Fluorocytosine;   Ancobon (TN);   Ancotil;   Formula=C4H4FN3O;   InChI=1S/C4H4FN3O/c5-2-1-7-4(9)8-3(2)6/h1H,(H3,6,7,8,9);   InChIKey=XRECTZIEBJDKEO-UHFFFAOYSA-N;   SMILES=Nc1nc(=O)[nH]cc1F;   flucytosina;   flucytosinum
 xref: CAS:2022-85-7 "ChemIDplus";   CAS:2022-85-7 "KEGG DRUG";   DrugBank:DB01099;   Drug_Central:1188 "DrugCentral";   HMDB:HMDB0015231;   KEGG:D00323;   LINCS:LSM-5878
 xref_mesh: MESH:D005437
 xref: PDBeChem:1LD;   PMID:11519290 "Europe PMC";   PMID:14871609 "Europe PMC";   PMID:18731030 "Europe PMC";   PMID:23576540 "Europe PMC";   PMID:25649231 "Europe PMC";   PMID:26201447 "Europe PMC";   PMID:28166217 "Europe PMC";   Patent:US2802005;   Patent:US2945038;   Patent:US3040026;   Wikipedia:Flucytosine


show annotations for term's descendants       view all columns           Sort by:
 
flucytosine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      application 19328
        pro-agent 8807
          prodrug 8597
            flucytosine 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    main group molecular entity 19610
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18278
                            inorganic hydride 17205
                              pnictogen hydride 17167
                                nitrogen hydride 17003
                                  azane 16694
                                    ammonia 16691
                                      organic amino compound 16690
                                        aromatic amine 13592
                                          aminopyrimidine 1051
                                            cytosine 929
                                              flucytosine 3
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