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ONTOLOGY REPORT - ANNOTATIONS


Term:epinastine
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Accession:CHEBI:51032 term browser browse the term
Definition:A benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.
Synonyms:exact_synonym: 9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine
 related_synonym: 3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepine;   Formula=C16H15N3;   InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18);   InChIKey=WHWZLSFABNNENI-UHFFFAOYSA-N;   SMILES=NC1=NCC2N1c1ccccc1Cc1ccccc21;   epinastina;   epinastinum
 xref: Beilstein:3593307 "Beilstein";   CAS:80012-43-7 "ChemIDplus";   DrugBank:DB00751;   Drug_Central:1027 "DrugCentral";   KEGG:D07900
 xref_mesh: MESH:C053090
 xref: Patent:GB2071095;   Patent:US4313931;   Reaxys:3593307 "Reaxys";   Wikipedia:Epinastine


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epinastine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B JBrowse link 4 22,225,123 22,307,577 RGD:6480464
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il13 interleukin 13 JBrowse link 10 38,982,909 38,985,466 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il5 interleukin 5 JBrowse link 10 39,066,716 39,069,587 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        pharmacological role 18794
          antagonist 16201
            histamine antagonist 4590
              epinastine 11
                R-epinastine 0
                S-epinastine 0
                epinastine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic molecule 19418
                              organic cyclic compound 19189
                                organic heterocyclic compound 18267
                                  organic heteropolycyclic compound 17572
                                    organic heterobicyclic compound 16245
                                      benzazepine 488
                                        epinastine 11
                                          R-epinastine 0
                                          S-epinastine 0
                                          epinastine hydrochloride 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.