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Accession:CHEBI:5195 term browser browse the term
Definition:A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera.
Synonyms:exact_synonym: 3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one
 related_synonym: 3-(5'-Nitrofurfuralamino)-2-oxazolidone;   3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone;   3-[(5-Nitrofurfurylidene)amino]-2-oxazolidone;   3-[(5-Nitrofurylidene)amino]-2-oxazolidone;   3-{[(5-Nitro-2-furanyl)methylene]amino}-2-oxazolidinone;   5-Nitro-N-(2-oxo-3-oxazolidinyl)-2-furanmethanimine;   FZL;   Formula=C8H7N3O5;   Furazolidona;   Furazolidonum;   Furoxone;   InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2;   InChIKey=PLHJDBGFXBMTGZ-UHFFFAOYSA-N;   N-(5-Nitro-2-furfurylidene)-3-amino-2-oxazolidone;   N-(5-Nitro-2-furfurylidene)-3-aminooxazolidine-2-one;   Nitrofurazolidone;   Nitrofurazolidonum;   SMILES=[O-][N+](=O)c1ccc(C=NN2CCOC2=O)o1
 xref: Beilstein:384794 "Beilstein";   CAS:67-45-8 "ChemIDplus";   CAS:67-45-8 "DrugBank";   CAS:67-45-8 "KEGG COMPOUND";   CAS:67-45-8 "KEGG DRUG";   CAS:67-45-8 "NIST Chemistry WebBook";   DrugBank:DB00614;   Drug_Central:1257 "DrugCentral";   HMDB:HMDB0014752;   KEGG:C07999;   KEGG:D00830;   LINCS:LSM-6543
 xref_mesh: MESH:D005664
 xref: PMID:10735922 "Europe PMC";   PMID:14500876 "Europe PMC";   PMID:15666977 "Europe PMC";   PMID:16225499 "Europe PMC";   PMID:17422910 "Europe PMC";   PMID:21817887 "Europe PMC";   PMID:22024820 "Europe PMC";   PMID:22177019 "Europe PMC";   PMID:22221615 "Europe PMC";   PMID:22226073 "Europe PMC";   PMID:22228494 "Europe PMC";   PMID:22240115 "Europe PMC";   PMID:22249086 "Europe PMC";   PMID:22260837 "Europe PMC";   PMID:22362365 "Europe PMC";   PMID:22759325 "Europe PMC";   PMID:22829809 "Europe PMC";   PMID:22868168 "Europe PMC";   PMID:22877600 "Europe PMC";   PMID:23112108 "Europe PMC";   PMID:23151414 "Europe PMC";   PMID:23153221 "Europe PMC";   PMID:23261742 "Europe PMC";   PMID:23279258 "Europe PMC";   PMID:23285433 "Europe PMC";   PMID:23376004 "Europe PMC";   PMID:23403439 "Europe PMC";   PMID:23418857 "Europe PMC";   PMID:23429422 "Europe PMC";   PMID:23461927 "Europe PMC";   Patent:GB735136;   Patent:US2742462;   Patent:US2759931;   Patent:US2927110;   Reaxys:384794 "Reaxys";   Wikipedia:Furazolidone

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furazolidone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        antimicrobial agent 17227
          nitrofuran antibiotic 43
            furazolidone 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic molecule 19434
                              organic cyclic compound 19201
                                organic heterocyclic compound 18270
                                  organic heteromonocyclic compound 16358
                                    furans 4122
                                      nitrofuran antibiotic 43
                                        furazolidone 12
paths to the root


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