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Accession:CHEBI:52010 term browser browse the term
Definition:A tertiary amino compound that is propylamine which is substituted at position 3 by a pyridin-2-yl group and a p-chlorophenyl group and in which the hydrogens attached to the nitrogen are replaced by methyl groups. A histamine H1 antagonist, it is used to relieve the symptoms of hay fever, rhinitis, urticaria, and asthma.
Synonyms:exact_synonym: 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
 related_synonym: 1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine;   1-(p-chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane;   2-[p-chloro-alpha-[2-(dimethylamino)ethyl]benzyl]pyridine;   3-(p-chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine;   Chlorphenamin;   Chlorpheniramine;   Clofeniramina;   Formula=C16H19ClN2;   Haynon;   InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3;   InChIKey=SOYKEARSMXGVTM-UHFFFAOYSA-N;   SMILES=CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1;   chlorophenylpyridamine;   chlorphenaminum;   chlorpheniraminum;   clorfenamina;   clorfeniramina;   gamma-(4-chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine;   gamma-(4-chlorophenyl)-gamma-(2-pyridyl)propyldimethylamine
 alt_id: CHEBI:3644;   CHEBI:52008
 xref: Beilstein:87362 "Beilstein";   CAS:132-22-9 "ChemIDplus";   CAS:132-22-9 "KEGG COMPOUND";   CAS:132-22-9 "NIST Chemistry WebBook";   DrugBank:DB01114 "SUBMITTER";   Drug_Central:616 "DrugCentral";   HMDB:HMDB0001944;   KEGG:C06905;   KEGG:D07398;   LINCS:LSM-1263
 xref_mesh: MESH:D002744
 xref: PMID:10796091 "Europe PMC";   PMID:11284026 "Europe PMC";   PMID:16119587 "Europe PMC";   PMID:16413139 "Europe PMC";   Patent:US2567245;   Patent:US2676964;   Patent:US2766174;   Reaxys:87362 "Reaxys";   Wikipedia:Chlorpheniramine

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chlorphenamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb4 ATP binding cassette subfamily B member 4 JBrowse link 4 22,133,984 22,192,687 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Hrh1 histamine receptor H 1 JBrowse link 4 146,374,596 146,458,148 RGD:6480464
G Hrh2 histamine receptor H 2 JBrowse link 17 10,912,959 10,931,389 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
dexchlorpheniramine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        pharmacological role 18755
          antagonist 15859
            histamine antagonist 4485
              chlorphenamine 12
                dexchlorpheniramine 1
                levochlorpheniramine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    main group molecular entity 19598
                      s-block molecular entity 19361
                        hydrogen molecular entity 19350
                          hydrides 18280
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17003
                                  azane 16693
                                    ammonia 16690
                                      organic amino compound 16689
                                        tertiary amino compound 8527
                                          chlorphenamine 12
                                            dexchlorpheniramine 1
                                            levochlorpheniramine 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.