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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
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Accession:CHEBI:52425 term browser browse the term
Definition:An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
Synonyms:related_synonym: EC 3.2.1.18 inhibitor;   EC 3.2.1.18 inhibitors;   N-acylneuraminate glycohydrolase inhibitor;   N-acylneuraminate glycohydrolase inhibitors;   Neuraminidase inhibitors;   acetylneuraminidase inhibitor;   acetylneuraminidase inhibitors;   acetylneuraminyl hydrolase inhibitor;   acetylneuraminyl hydrolase inhibitors;   alpha-neuraminidase inhibitor;   alpha-neuraminidase inhibitors;   exo-alpha-sialidase (EC 3.2.1.18) inhibitors;   exo-alpha-sialidase inhibitor;   exo-alpha-sialidase inhibitors;   neuraminidase inhibitor;   sialidase inhibitor;   sialidase inhibitors


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Path 1
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      biological role 0
        antimicrobial agent 0
          antimicrobial drug 0
            antiviral drug 0
              EC 3.2.1.18 (exo-alpha-sialidase) inhibitor 0
                (2S)-2,7-dihydroxy-5-methoxy-6,8-dimethylflavanone 0
                (2S)-5,7-dihydroxy-6,8-dimethylflavanone 0
                (2S)-6-formyl-8-methyl-7-O-methylpinocembrin 0
                (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone 0
                (2S,3S)-3,5,7-trihydroxy-6,8-dimethylflavanone 0
                (5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone 0
                (E)-4,2',4'-trihydroxy-6'-methoxy-3',5'-dimethylchalcone 0
                2',4'-dihydroxy-3'-methyl-6'-methoxychalcone 0
                2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone 0
                5alpha-ergosta-7,22-dien-3beta-ol 0
                7-hydroxy-5-methoxy-6,8-dimethylflavone 0
                7-hydroxy-5-methoxy-6,8-dimethylisoflavone 0
                FR191512 0
                N-acetylneuraminic acid + 0
                apiin + 0
                fattiviracin A1 0
                fluvirucin A1 + 0
                ganoderone C 0
                oseltamivir + 0
                oseltamivir acid 0
                peramivir 0
                peramivir hydrate + 0
                strongylin A 0
                zanamivir 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 0
    role 0
      application 0
        pharmaceutical 0
          drug 0
            antiinfective agent 0
              antimicrobial drug 0
                antiviral drug 0
                  EC 3.2.1.18 (exo-alpha-sialidase) inhibitor 0
                    (2S)-2,7-dihydroxy-5-methoxy-6,8-dimethylflavanone 0
                    (2S)-5,7-dihydroxy-6,8-dimethylflavanone 0
                    (2S)-6-formyl-8-methyl-7-O-methylpinocembrin 0
                    (2S)-8-formyl-5-hydroxy-7-methoxy-6-methylflavanone 0
                    (2S,3S)-3,5,7-trihydroxy-6,8-dimethylflavanone 0
                    (5R)-5-hydroxy-7-(4''-hydroxy-3''-methoxyphenyl)-1-phenyl-3-heptanone 0
                    (E)-4,2',4'-trihydroxy-6'-methoxy-3',5'-dimethylchalcone 0
                    2',4'-dihydroxy-3'-methyl-6'-methoxychalcone 0
                    2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone 0
                    5alpha-ergosta-7,22-dien-3beta-ol 0
                    7-hydroxy-5-methoxy-6,8-dimethylflavone 0
                    7-hydroxy-5-methoxy-6,8-dimethylisoflavone 0
                    FR191512 0
                    N-acetylneuraminic acid + 0
                    apiin + 0
                    fattiviracin A1 0
                    fluvirucin A1 + 0
                    ganoderone C 0
                    oseltamivir + 0
                    oseltamivir acid 0
                    peramivir 0
                    peramivir hydrate + 0
                    strongylin A 0
                    zanamivir 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.