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ONTOLOGY REPORT - ANNOTATIONS


Term:ginkgetin
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Accession:CHEBI:5353 term browser browse the term
Definition:A biflavonoid that is the 7,4'-dimethyl ether derivative of amentoflavone. Isolated from Ginkgo biloba and Dioon, it exhibits anti-HSV-1, antineoplastic and inhibitory activities towards arachidonate 5-lipoxygenase and cyclooxygenase 2.
Synonyms:exact_synonym: 5,7-dihydroxy-8-[5-(5-hydroxy-7-methoxy-4-oxo-4H-chromen-2-yl)-2-methoxyphenyl]-2-(4-hydroxyphenyl)-4H-chromen-4-one
 related_synonym: 4''',5,5'',7''-tetrahydroxy-4',7-dimethoxy-(3'->8'')-biflavone;   5,7-dihydroxy-8-(5-(5-hydroxy-7-methoxy-4-oxo-4H-1-benzopyran-2-yl)-2-methoxyphenyl)-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one;   Amentoflavone 7,4'-dimethyl ether;   Formula=C32H22O10;   InChI=1S/C32H22O10/c1-39-18-10-20(34)30-23(37)13-27(41-28(30)11-18)16-5-8-25(40-2)19(9-16)29-21(35)12-22(36)31-24(38)14-26(42-32(29)31)15-3-6-17(33)7-4-15/h3-14,33-36H,1-2H3;   InChIKey=AIFCFBUSLAEIBR-UHFFFAOYSA-N;   SMILES=COc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(OC)c(c1)-c1c(O)cc(O)c2c1oc(cc2=O)-c1ccc(O)cc1
 alt_id: CHEBI:65965
 xref: CAS:481-46-9 "ChemIDplus";   CAS:481-46-9 "KEGG COMPOUND";   KEGG:C10048;   KNApSAcK:C00001044;   LINCS:LSM-42758;   LIPID_MAPS_instance:LMPK12040003 "LIPID MAPS"
 xref_mesh: MESH:C077458
 xref: PMID:1329635 "Europe PMC";   PMID:16327145 "Europe PMC";   PMID:9134745 "Europe PMC";   Reaxys:381052 "Reaxys"


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ginkgetin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ftl1 ferritin light chain 1 JBrowse link 1 101,448,190 101,450,034 RGD:6480464
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:6480464
G Th tyrosine hydroxylase JBrowse link 1 216,073,034 216,080,287 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        biochemical role 19125
          metabolite 19093
            ginkgetin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  oxacycle 16944
                                    benzopyran 9466
                                      1-benzopyran 9161
                                        flavonoid 6311
                                          flavones 4140
                                            hydroxyflavone 4129
                                              amentoflavone 26
                                                ginkgetin 6
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