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ONTOLOGY REPORT - ANNOTATIONS


Term:glipizide
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Accession:CHEBI:5384 term browser browse the term
Definition:An N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus.
Synonyms:exact_synonym: N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-5-methylpyrazine-2-carboxamide
 related_synonym: 1-cyclohexyl-3-({p-[2-(5-methylpyrazinecarboxamido)ethyl]phenyl}sulfonyl)urea;   Aldiab;   CP 28,720;   CP 28720;   Digrin;   Dipazide;   Formula=C21H27N5O4S;   Glibenese;   Glibetin;   Glican;   Glidiab;   Glipid;   Gluco-Rite;   Glucolip;   Glucotrol;   Glucozide;   Glupitel;   Glupizide;   Glyde;   Glydiazinamide;   InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28);   InChIKey=ZJJXGWJIGJFDTL-UHFFFAOYSA-N;   K 4024;   Melizide;   Mindiab;   Minidab;   Minidiab;   Minodiab;   N-{4-[beta-(5-methylpyrazine-2-carboxamido)ethyl]benzenesulphonyl}-N'-cyclohexylurea;   Napizide;   Ozidia;   SMILES=Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1;   Sucrazide;   glipizida;   glipizidum
 xref: CAS:29094-61-9 "ChemIDplus";   DrugBank:DB01067;   Drug_Central:1301 "DrugCentral";   HMDB:HMDB0015200;   KEGG:D00335;   LINCS:LSM-2251
 xref_mesh: MESH:D005913
 xref: PMID:11147395 "Europe PMC";   PMID:20797618 "Europe PMC";   PMID:23230096 "Europe PMC";   PMID:24418334 "Europe PMC";   PMID:24444583 "Europe PMC";   PMID:2665487 "Europe PMC";   PMID:3143256 "Europe PMC";   PMID:389600 "Europe PMC";   PMID:3923454 "Europe PMC";   PMID:7660535 "Europe PMC";   Patent:DE2012138;   Patent:US3669966;   Reaxys:903495 "Reaxys";   Wikipedia:Glipizide


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glipizide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      application 19336
        pharmaceutical 19211
          drug 19211
            hypoglycemic agent 3991
              glipizide 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            organic group 18414
                              organic divalent group 18406
                                organodiyl group 18406
                                  carbonyl group 18295
                                    carbonyl compound 18295
                                      carboxylic acid 17963
                                        carboacyl group 17074
                                          univalent carboacyl group 17074
                                            carbamoyl group 16804
                                              carboxamide 16804
                                                monocarboxylic acid amide 14167
                                                  urea 4955
                                                    ureas 4952
                                                      N-sulfonylurea 103
                                                        glipizide 3
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