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ONTOLOGY REPORT - ANNOTATIONS


Term:glyburide
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Accession:CHEBI:5441 term browser browse the term
Definition:An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Synonyms:exact_synonym: 5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
 related_synonym: 1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea;   1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea;   5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide;   Diabeta;   Formula=C23H28ClN3O5S;   Glynase;   InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29);   InChIKey=ZNNLBTZKUZBEKO-UHFFFAOYSA-N;   Micronase;   SMILES=COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1;   glibenclamida;   glibenclamide;   glibenclamidum
 xref: Beilstein:2230085 "Beilstein";   CAS:10238-21-8 "ChemIDplus";   CAS:10238-21-8 "KEGG COMPOUND";   DrugBank:DB01016;   Drug_Central:1314 "DrugCentral";   KEGG:C07022;   KEGG:D00336;   LINCS:LSM-2811
 xref_mesh: MESH:D005905
 xref: PMID:16081479 "Europe PMC";   PMID:20797618 "Europe PMC";   Patent:NL6603398;   Patent:NL6610580;   Patent:US3454635;   Wikipedia:Glibenclamide


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glyburide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CFTR CF transmembrane conductance regulator JBrowse link 14 56,290,417 56,452,919 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 223
    role 223
      application 188
        pharmaceutical 185
          drug 185
            hypoglycemic agent 3
              glyburide 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 223
    subatomic particle 223
      composite particle 223
        hadron 223
          baryon 223
            nucleon 223
              atomic nucleus 223
                atom 223
                  main group element atom 216
                    p-block element atom 216
                      carbon group element atom 205
                        carbon atom 204
                          organic molecular entity 204
                            organic group 153
                              organic divalent group 152
                                organodiyl group 152
                                  carbonyl group 152
                                    carbonyl compound 152
                                      carboxylic acid 112
                                        carboacyl group 47
                                          univalent carboacyl group 47
                                            carbamoyl group 44
                                              carboxamide 44
                                                monocarboxylic acid amide 19
                                                  urea 9
                                                    ureas 7
                                                      N-sulfonylurea 1
                                                        glyburide 1
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