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Term:homovanillic acid
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Accession:CHEBI:545959 term browser browse the term
Definition:A monocarboxylic acid that is the 3-O-methyl ether of (3,4-dihydroxyphenyl)acetic acid. It is a catecholamine metabolite.
Synonyms:exact_synonym: 2-(4-hydroxy-3-methoxyphenyl)acetic acid
 related_synonym: (4-hydroxy-3-methoxyphenyl)acetic acid;   3-Methoxy-4-hydroxyphenylacetate;   3-Methoxy-4-hydroxyphenylacetic acid;   4-Hydroxy-3-methoxybenzeneacetic acid;   Formula=C9H10O4;   HVA;   InChI=1S/C9H10O4/c1-13-8-4-6(5-9(11)12)2-3-7(8)10/h2-4,10H,5H2,1H3,(H,11,12);   InChIKey=QRMZSPFSDQBLIX-UHFFFAOYSA-N;   SMILES=COc1cc(CC(O)=O)ccc1O;   Vanillacetic acid
 alt_id: CHEBI:5758
 xref: CAS:306-08-1 "ChemIDplus";   CAS:306-08-1 "KEGG COMPOUND";   HMDB:HMDB0000118;   KEGG:C05582;   KNApSAcK:C00029504
 xref_mesh: MESH:D006719
 xref: MetaCyc:CPD-7651;   PMID:14688447 "Europe PMC";   PMID:24007816 "Europe PMC";   PMID:24416192 "Europe PMC";   PMID:24423636 "Europe PMC";   PMID:8353435 "Europe PMC";   Reaxys:2213447 "Reaxys";   Wikipedia:Homovanillic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:133744

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homovanillic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Maob monoamine oxidase B JBrowse link X 6,430,694 6,533,520 RGD:6480464
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Oprm1 opioid receptor, mu 1 JBrowse link 1 43,454,803 43,704,948 RGD:6480464
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Tfam transcription factor A, mitochondrial JBrowse link 20 18,594,057 18,606,106 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        poison 17833
          toxin 13562
            phenylacetic acid 1151
              (3,4-dihydroxyphenyl)acetic acid 18
                homovanillic acid 9
                  N-octylhomovanillamide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        hydroxy carboxylic acid 3586
                                          hydroxy monocarboxylic acid 3586
                                            dihydroxy monocarboxylic acid 255
                                              dihydroxyphenylacetic acid 18
                                                (3,4-dihydroxyphenyl)acetic acid 18
                                                  homovanillic acid 9
                                                    N-octylhomovanillamide 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.