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Term:sodium aurothiomalate
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Accession:CHEBI:5516 term browser browse the term
Definition:A variable mixture of the mono- and di-sodium salts of aurothiomalic acid. It is used for treatment of rheumatoid arthritis.
Synonyms:related_synonym: Gold sodium thiomalate;   Myochrysine (TN)
 alt_id: CHEBI:75985
 xref: CAS:12244-57-4 "ChemIDplus";   CAS:12244-57-4 "KEGG DRUG";   KEGG:D00992
 xref_mesh: MESH:D006052
 xref: PMID:19192274 "Europe PMC";   PMID:19194667 "Europe PMC";   PMID:20099230 "Europe PMC";   PMID:20225983 "Europe PMC";   PMID:20386869 "Europe PMC";   PMID:21467262 "Europe PMC";   PMID:23686086 "Europe PMC";   PMID:2571649 "Europe PMC";   PMID:2822844 "Europe PMC";   PMID:2840130 "Europe PMC";   PMID:2977403 "Europe PMC";   PMID:3134898 "Europe PMC";   PMID:3936929 "Europe PMC";   PMID:445303 "Europe PMC";   PMID:6318557 "Europe PMC";   PMID:6427463 "Europe PMC";   PMID:6812186 "Europe PMC";   PMID:7525650 "Europe PMC";   PMID:7720377 "Europe PMC";   PMID:818413 "Europe PMC";   PMID:8445531 "Europe PMC";   PMID:92161 "Europe PMC";   Wikipedia:Sodium_aurothiomalate


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sodium aurothiomalate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ackr3 atypical chemokine receptor 3 JBrowse link 9 97,355,881 97,367,455 RGD:6480464
G Adora2a adenosine A2a receptor JBrowse link 20 14,265,251 14,282,873 RGD:6480464
G Amigo2 adhesion molecule with Ig like domain 2 JBrowse link 7 138,704,124 138,707,221 RGD:6480464
G Antxr1 ANTXR cell adhesion molecule 1 JBrowse link 4 118,946,267 119,131,202 RGD:6480464
G Aox1 aldehyde oxidase 1 JBrowse link 9 64,929,682 65,007,872 RGD:6480464
G Bcl2a1 BCL2-related protein A1 JBrowse link 8 96,551,424 96,559,527 RGD:6480464
G Bst2 bone marrow stromal cell antigen 2 JBrowse link 16 19,938,781 19,942,353 RGD:6480464
G Ccl20 C-C motif chemokine ligand 20 JBrowse link 9 88,918,359 88,921,017 RGD:6480464
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:6480464
G Ccn5 cellular communication network factor 5 JBrowse link 3 160,207,969 160,219,316 RGD:6480464
G Cd28 Cd28 molecule JBrowse link 9 67,546,408 67,573,858 RGD:6480464
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6480464
G Clgn calmegin JBrowse link 19 24,545,257 24,578,527 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Colec12 collectin sub-family member 12 JBrowse link 18 867,048 1,054,047 RGD:6480464
G Cxcl1 C-X-C motif chemokine ligand 1 JBrowse link 14 18,743,678 18,745,457 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cxcl3 chemokine (C-X-C motif) ligand 3 JBrowse link 14 18,820,168 18,839,659 RGD:6480464
G Cxcr4 C-X-C motif chemokine receptor 4 JBrowse link 13 45,314,952 45,318,856 RGD:6480464
G Ddx10 DEAD-box helicase 10 JBrowse link 8 57,667,472 57,830,504 RGD:6480464
G Ddx58 DEXD/H-box helicase 58 JBrowse link 5 56,486,584 56,536,898 RGD:6480464
G Efemp1 EGF containing fibulin extracellular matrix protein 1 JBrowse link 14 113,202,382 113,294,993 RGD:6480464
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 JBrowse link 7 94,479,931 94,563,086 RGD:6480464
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 JBrowse link 8 129,201,000 129,232,436 RGD:6480464
G Fbl fibrillarin JBrowse link 1 85,103,519 85,112,619 RGD:6480464
G Fbln1 fibulin 1 JBrowse link 7 126,096,793 126,176,468 RGD:6480464
G Fgf7 fibroblast growth factor 7 JBrowse link 3 118,315,859 118,368,464 RGD:6480464
G Gbp1 guanylate binding protein 1 JBrowse link 2 248,343,334 248,423,402 RGD:6480464
G Gpm6b glycoprotein m6b JBrowse link X 29,604,607 29,751,174 RGD:6480464
G Gsdme gasdermin E JBrowse link 4 79,934,075 79,999,678 RGD:6480464
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 JBrowse link 4 88,606,851 88,649,424 RGD:6480464
G Hilpda hypoxia inducible lipid droplet-associated JBrowse link 4 56,547,600 56,550,584 RGD:6480464
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 JBrowse link 13 111,946,626 111,996,536 RGD:6480464
G Ifi27 interferon, alpha-inducible protein 27 JBrowse link 6 127,327,959 127,334,430 RGD:6480464
G Ifi35 interferon-induced protein 35 JBrowse link 10 89,358,376 89,366,628 RGD:6480464
G Ifi44 interferon-induced protein 44 JBrowse link 2 256,897,765 256,915,591 RGD:6480464
G Ifi44l interferon-induced protein 44-like JBrowse link 2 256,948,722 256,979,573 RGD:6480464
G Ifih1 interferon induced with helicase C domain 1 JBrowse link 3 48,557,696 48,604,097 RGD:6480464
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 JBrowse link 1 252,906,234 252,911,377 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6480464
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Irf7 interferon regulatory factor 7 JBrowse link 1 214,249,388 214,252,909 RGD:6480464
G Isg15 ISG15 ubiquitin-like modifier JBrowse link 5 173,624,862 173,629,124 RGD:6480464
G Isg20 interferon stimulated exonuclease gene 20 JBrowse link 1 140,602,553 140,608,892 RGD:6480464
G Lamb3 laminin subunit beta 3 JBrowse link 13 112,031,614 112,073,187 RGD:6480464
G Lxn latexin JBrowse link 2 164,628,565 164,634,434 RGD:6480464
G Ly6e lymphocyte antigen 6 family member E JBrowse link 7 116,355,426 116,359,862 RGD:6480464
G Marcks myristoylated alanine rich protein kinase C substrate JBrowse link 20 42,966,140 42,971,838 RGD:6480464
G Met MET proto-oncogene, receptor tyrosine kinase JBrowse link 4 44,747,467 44,854,628 RGD:6480464
G Mmp10 matrix metallopeptidase 10 JBrowse link 8 5,734,348 5,742,243 RGD:6480464
G Mx2 MX dynamin like GTPase 2 JBrowse link 11 38,035,306 38,066,185 RGD:6480464
G Ndufa4l2 NDUFA4, mitochondrial complex associated like 2 JBrowse link 7 70,821,904 70,824,085 RGD:6480464
G Nmb neuromedin B JBrowse link 1 142,721,263 142,724,646 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 JBrowse link 5 63,781,801 63,822,890 RGD:6480464
G Oas1a 2'-5' oligoadenylate synthetase 1A JBrowse link 12 41,200,680 41,211,393 RGD:6480464
G Oasl 2'-5'-oligoadenylate synthetase-like JBrowse link 12 47,444,138 47,456,680 RGD:6480464
G Olfml2b olfactomedin-like 2B JBrowse link 13 88,995,301 89,032,487 RGD:6480464
G Phgdh phosphoglycerate dehydrogenase JBrowse link 2 200,484,245 200,513,564 RGD:6480464
G Plpp3 phospholipid phosphatase 3 JBrowse link 5 124,690,214 124,765,499 RGD:6480464
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 JBrowse link 4 133,285,552 133,323,755 RGD:6480464
G Ptges prostaglandin E synthase JBrowse link 3 9,727,408 9,738,752 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rarres1 retinoic acid receptor responder 1 JBrowse link 2 164,650,722 164,684,982 RGD:6480464
G Rgs4 regulator of G-protein signaling 4 JBrowse link 13 88,054,817 88,061,108 RGD:6480464
G Ripk2 receptor-interacting serine-threonine kinase 2 JBrowse link 5 29,838,713 29,870,390 RGD:6480464
G Rnf19b ring finger protein 19B JBrowse link 5 147,246,032 147,270,892 RGD:6480464
G Rsad2 radical S-adenosyl methionine domain containing 2 JBrowse link 6 45,655,947 45,669,083 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Sms spermine synthase JBrowse link X 40,363,646 40,415,110 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Spon1 spondin 1 JBrowse link 1 178,568,777 178,935,715 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6480464
G Sts steroid sulfatase JBrowse link X 45,420,418 45,428,748 RGD:6480464
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:6480464
G Thbs2 thrombospondin 2 JBrowse link 1 56,653,929 56,683,571 RGD:6480464
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:6480464
G Tnfaip2 TNF alpha induced protein 2 JBrowse link 6 135,890,869 135,903,647 RGD:6480464
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:6480464
G Txnrd2 thioredoxin reductase 2 JBrowse link 11 86,667,994 86,716,063 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    chemical entity 19714
      chemical substance 11495
        mixture 10815
          sodium aurothiomalate 87
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic ion 7897
                              organic anion 2229
                                carboxylic acid anion 1828
                                  dicarboxylic acid anion 213
                                    dicarboxylic acid dianion 213
                                      C4-dicarboxylate 87
                                        aurothiomalate(2-) 87
                                          disodium aurothiomalate 87
                                            sodium aurothiomalate 87
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.