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ONTOLOGY REPORT - ANNOTATIONS


Term:alcuronium
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Accession:CHEBI:55313 term browser browse the term
Definition:An indole alkaloid of the curare family. A neuroblocker, it is often used in chloride form as an anesthesia adjuvant.
Synonyms:exact_synonym: (1R,3aR,9Z,10S,11aS,12R,14aR,19aS,20Z,20bS,21S,22aS,23E,26E)-23,26-bis(2-hydroxyethylidene)-1,12-di(prop-2-en-1-yl)-1,2,3,10,11,11a,12,13,14,21,22,22a-dodecahydro-19aH,20bH-1,21:10,12-diethanodipyrrolo[3,2-f:3,2-f'][1,5]diazocino[3,2,1-jk:7,6,5-j'k']dicarbazole-1,12-diium
 related_synonym: 4,4'-Didemethyl-4,4'-di-2-propenyl-toxiferine I (9CI);   Alcuronum;   Alloferine;   Diallylbis(nortoxiferine);   Diallylnortoxiferine;   Diallyltoxiferine;   Formula=C44H50N4O2;   InChI=1S/C44H50N4O2/c1-3-17-47-19-15-43-35-9-5-7-11-37(35)45-26-34-32-24-40-44(16-20-48(40,18-4-2)28-30(32)14-22-50)36-10-6-8-12-38(36)46(42(34)44)25-33(41(43)45)31(23-39(43)47)29(27-47)13-21-49/h3-14,25-26,31-32,39-42,49-50H,1-2,15-24,27-28H2/q+2/b29-13-,30-14-,33-25-,34-26-/t31-,32-,39-,40-,41-,42-,43+,44+,47-,48-/m0/s1;   InChIKey=MUQUYTSLDVKIOF-CHJKCJHBSA-N;   N,N'-Diallylnortoxiferinium;   N,N'-diallyl-bis-nor-toxiferine;   SMILES=[H][C@]12C[C@@]3([H])[C@@]4(CC[N@@+]3(CC=C)C\\C1=C\\CO)c1ccccc1N1\\C=C3\\[C@@]5([H])C[C@@]6([H])[C@@]7(CC[N@@+]6(CC=C)C\\C5=C\\CO)c5ccccc5N(\\C=C2/[C@@]41[H])[C@@]37[H]
 xref: Beilstein:4101239 "Beilstein";   CAS:23214-96-2 "ChemIDplus"
 xref_mesh: MESH:D000443
 xref: PMID:12039641 "Europe PMC";   PMID:6196640 "Europe PMC";   PMID:7818127 "Europe PMC";   Reaxys:4101239 "Reaxys"


show annotations for term's descendants       view all columns           Sort by:
 
alcuronium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrm4 cholinergic receptor, muscarinic 4 JBrowse link 3 80,833,272 80,841,165 RGD:6480464
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit JBrowse link 3 176,533,182 176,547,965 RGD:6480464
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit JBrowse link 2 189,088,570 189,096,785 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      biological role 19694
        biochemical role 19192
          metabolite 19164
            alkaloid 5281
              indole alkaloid 1832
                alcuronium 3
                  alcuronium bromide 0
                  alcuronium chloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    p-block element atom 19630
                      carbon group element atom 19523
                        carbon atom 19517
                          organic molecular entity 19517
                            organic group 18427
                              cyclic organic group 1832
                                organic heterobicyclic ring 1832
                                  indole skeleton 1832
                                    indole alkaloid 1832
                                      alcuronium 3
                                        alcuronium bromide 0
                                        alcuronium chloride 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.