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ONTOLOGY REPORT - ANNOTATIONS


Term:O-acetyl-L-carnitine
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Accession:CHEBI:57589 term browser browse the term
Definition:An O-acyl-L-carnitine where the acyl group specified is acetyl. It facilitates movement of acetyl-CoA into the matrices of mammalian mitochondria during the oxidation of fatty acids.
Synonyms:exact_synonym: (3R)-3-(acetyloxy)-4-(trimethylazaniumyl)butanoate
 related_synonym: Acetyl-L-carnitine;   Acetylcarnitine;   Formula=C9H17NO4;   InChI=1S/C9H17NO4/c1-7(11)14-8(5-9(12)13)6-10(2,3)4/h8H,5-6H2,1-4H3/t8-/m1/s1;   InChIKey=RDHQFKQIGNGIED-MRVPVSSYSA-N;   L-Acetylcarnitine;   L-Carnitine acetyl ester;   L-O-Acetylcarnitine;   O-acetyl-(R)-carnitine;   R-Acetylcarnitine;   SMILES=CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C
 alt_id: MESH:D000108
 xref: Beilstein:3667658 "Beilstein";   CAS:3040-38-8 "ChemIDplus";   Drug_Central:64 "DrugCentral";   HMDB:HMDB0000201;   KEGG:C02571
 xref_mesh: MESH:D000108
 xref: MetaCyc:O-ACETYLCARNITINE;   PMID:22770225 "Europe PMC";   Reaxys:3667658 "Reaxys";   Wikipedia:Acetyl-L-carnitine
 cyclic_relationship: is_enantiomer_of CHEBI:86045


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O-acetyl-L-carnitine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 JBrowse link 15 27,849,943 27,852,083 RGD:6480464
G Atp6v1f ATPase H+ transporting V1 subunit F JBrowse link 4 56,744,563 56,747,657 RGD:6480464
G C1qa complement C1q A chain JBrowse link 5 155,261,254 155,264,101 RGD:6480464
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:6480464
G Ctss cathepsin S JBrowse link 2 197,655,780 197,679,768 RGD:6480464
G Cxcl14 C-X-C motif chemokine ligand 14 JBrowse link 17 9,109,731 9,117,754 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hmox2 heme oxygenase 2 JBrowse link 10 10,990,034 11,035,493 RGD:6480464
G Hspb1 heat shock protein family B (small) member 1 JBrowse link 12 23,839,390 23,841,051 RGD:6480464
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Mt-co1 mitochondrially encoded cytochrome c oxidase I JBrowse link MT 5,323 6,867 RGD:6480464
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:6480464
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Pah phenylalanine hydroxylase JBrowse link 7 28,066,639 28,129,772 RGD:6480464
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:6480464
G Psmb6 proteasome 20S subunit beta 6 JBrowse link 10 57,131,339 57,133,685 RGD:6480464
G Ptma prothymosin alpha JBrowse link 9 93,545,396 93,549,436 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rps17 ribosomal protein S17 JBrowse link 1 143,167,329 143,169,915 RGD:6480464
G Skap2 src kinase associated phosphoprotein 2 JBrowse link 4 81,816,778 81,968,832 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Tnni3 troponin I3, cardiac type JBrowse link 1 72,882,806 72,886,490 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            butyrate 80
              carnitine 80
                O-acetyl-L-carnitine 38
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    main group molecular entity 19598
                      s-block molecular entity 19361
                        hydrogen molecular entity 19350
                          hydrides 18280
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17003
                                  ammonium 8225
                                    ammonium ion derivative 8220
                                      quaternary ammonium ion 5061
                                        quaternary nitrogen compound 545
                                          ammonium betaine 270
                                            amino-acid betaine 183
                                              carnitine 80
                                                O-acylcarnitine 42
                                                  O-acyl-L-carnitine 38
                                                    saturated fatty acyl-L-carnitine 38
                                                      O-acetyl-L-carnitine 38
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.