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ONTOLOGY REPORT - ANNOTATIONS


Term:ecothiopate iodide
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Accession:CHEBI:59849 term browser browse the term
Definition:The iodide salt of ecothiopate. An irreversible acetylcholinesterase inhibitor, it is used an ocular antihypertensive in the treatment of open-angle glaucoma, particularly when other drugs have proved inadequate.
Synonyms:exact_synonym: 2-[(diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethanaminium iodide
 related_synonym: (2-mercaptoethyl)trimethylammonium iodidie O,O-diethyl phosphorothioate;   2-[(diethoxyphosphinyl)thio]-N,N,N-trimethylethanaminium iodide;   2-diethoxy-phosphinylthioethyl-trimethylammonium iodide;   Formula=C9H23INO3PS;   InChI=1S/C9H23NO3PS.HI/c1-6-12-14(11,13-7-2)15-9-8-10(3,4)5;/h6-9H2,1-5H3;1H/q+1;/p-1;   InChIKey=OVXQHPWHMXOFRD-UHFFFAOYSA-M;   N-(2-(diethoxyphosphinylthio)ethyl)trimethylammonium iodide;   O,O-diethyl S-2-trimethylammonium ethylphosphonothiolate iodide;   S-(2-(N,N,N-trimethylammonio)ethyl) O,O-diethylphosphorothiolate iodide;   S-(2-dimethylaminoethyl)-O,O-diethylphosphorothioate methiodide;   S-beta-dimethylaminoethyl-O,O-diethylthionophosphate methiodide;   SMILES=[I-].CCOP(=O)(OCC)SCC[N+](C)(C)C;   diethoxyphosphinylthiocholine iodide;   diethoxyphosphoryl-thiocholine iodide;   ecothiopati iodidum;   ecothiophate iodide;   iodure d'ecothiopate;   ioduro de ecotiopato
 xref: Beilstein:3762945 "Beilstein";   CAS:513-10-0 "ChemIDplus";   CAS:513-10-0 "KEGG DRUG";   DrugBank:DB01057;   KEGG:D02193
 xref_mesh: MESH:D004456
 xref: Patent:US2911430


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ecothiopate iodide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Nceh1 neutral cholesterol ester hydrolase 1 JBrowse link 2 112,868,834 112,932,622 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      biological role 19693
        pharmacological role 18802
          neurotransmitter agent 16410
            miotic 65
              ecothiopate iodide 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    main group molecular entity 19628
                      s-block molecular entity 19393
                        hydrogen molecular entity 19382
                          hydrides 18296
                            inorganic hydride 17211
                              pnictogen hydride 17174
                                nitrogen hydride 17010
                                  ammonium 8221
                                    ammonium ion derivative 8216
                                      quaternary ammonium ion 5059
                                        cholines 4765
                                          choline 3507
                                            choline ester 123
                                              phosphocholines 123
                                                ecothiopate 4
                                                  ecothiopate iodide 4
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