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ONTOLOGY REPORT - ANNOTATIONS


Term:fondaparinux
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Accession:CHEBI:61033 term browser browse the term
Definition:A synthetic pentasaccharide which, apart from the O-methyl group at the reducing end of the molecule, consists of monomeric sugar units which are identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparin and heparan sulfate.
Synonyms:exact_synonym: methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-beta-D-glucopyranuronosyl-(1->4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranosyl-(1->4)-2-O-sulfo-alpha-L-idopyranuronosyl-(1->4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside
 related_synonym: Formula=C31H53N3O49S8;   InChI=1S/C31H53N3O49S8/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18-,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-/m1/s1;   InChIKey=KANJSNBRCNMZMV-ABRZTLGGSA-N;   Natural heparin pentasaccharide;   SMILES=CO[C@H]1O[C@H](COS(O)(=O)=O)[C@@H](O[C@@H]2O[C@H]([C@@H](O[C@H]3O[C@H](COS(O)(=O)=O)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@H]5O[C@H](COS(O)(=O)=O)[C@@H](O)[C@H](O)[C@H]5NS(O)(=O)=O)[C@H](O)[C@H]4O)C(O)=O)[C@H](OS(O)(=O)=O)[C@H]3NS(O)(=O)=O)[C@H](O)[C@H]2OS(O)(=O)=O)C(O)=O)[C@H](O)[C@H]1NS(O)(=O)=O;   fondaparin
 alt_id: CHEBI:44566
 xref: CAS:104993-28-4 "ChemIDplus";   Drug_Central:1236 "DrugCentral"
 xref_mesh: MESH:C438268
 xref: PDBeChem:NTO;   PMID:29531454 "Europe PMC";   PMID:30169652 "Europe PMC";   PMID:30656269 "Europe PMC";   PMID:31030756 "Europe PMC";   PMID:31251320 "Europe PMC";   PMID:31549765 "Europe PMC";   PMID:31782283 "Europe PMC";   PPR:PPR103739 "Europe PMC";   Reaxys:9381701 "Reaxys";   Wikipedia:Fondaparinux
 cyclic_relationship: is_conjugate_acid_of CHEBI:61038


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fondaparinux term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      application 19350
        pharmaceutical 19224
          drug 19224
            hematologic agent 4260
              anticoagulant 4050
                fondaparinux 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      chalcogen 19337
                        oxygen atom 19298
                          oxygen molecular entity 19298
                            hydroxides 19053
                              oxoacid 18117
                                chalcogen oxoacid 11406
                                  sulfur oxoacid 10998
                                    sulfuric acid 7916
                                      sulfuric acid derivative 7916
                                        sulfates 7913
                                          organic sulfate 1809
                                            carbohydrate sulfate 1280
                                              oligosaccharide sulfate 2
                                                normethylfondaparinux 1
                                                  fondaparinux 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.