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Accession:CHEBI:61058 term browser browse the term
Definition:A derivative of L-tyrosine having a methyl group at the alpha-position and an additional hydroxy group at the 3-position on the phenyl ring.
Synonyms:related_synonym: (2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid;   (S)-(-)-alpha-Methyldopa;   3-Hydroxy-alpha-methyl-L-tyrosine;   AMD;   Alpha medopa;   Alphamethyldopa;   Formula=C10H13NO4;   InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1;   InChIKey=CJCSPKMFHVPWAR-JTQLQIEISA-N;   L(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine;   L-(alpha-Md);   L-2-Amino-2-methyl-3-(3,4-dihydroxyphenyl)propionic acid;   L-alpha-Methyl-3,4-dihydroxyphenylalanine;   L-alpha-Methyldopa;   Methyl-L-dopa;   Methyldopa anhydrous;   SMILES=C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O;   alpha-Methyl dopa;   alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine;   alpha-Methyldihydroxyphenylalanine;   alpha-Methyldopa;   l-3-(3,4-Dihydroxyphenyl)-2-methylalanine;   levo-3-(3,4-Dihydroxyphenyl)-2-methylalanine;   methyldopa;   methyldopum;   metildopa
 xref: CAS:555-30-6 "ChemIDplus";   CAS:555-30-6 "KEGG COMPOUND";   DrugBank:DB00968;   Drug_Central:1762 "DrugCentral";   HMDB:HMDB0011754;   KEGG:C07194;   KEGG:D08205;   LINCS:LSM-5596
 xref_mesh: MESH:D008750
 xref: PMID:10576686 "Europe PMC";   PMID:11901210 "Europe PMC";   PMID:29438107 "Europe PMC";   PMID:8301021 "Europe PMC";   Reaxys:2807721 "Reaxys";   Wikipedia:Methyldopa

show annotations for term's descendants       view all columns           Sort by:
alpha-methyl-L-dopa term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Gsta1 glutathione S-transferase alpha 1 JBrowse link 9 27,366,404 27,381,004 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Ren renin JBrowse link 13 50,502,724 50,513,953 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        hapten 2969
          alpha-methyl-L-dopa 6
            3-methoxy-alpha-methyl-L-tyrosine 0
            alpha-methyl-L-dopa ethyl ester 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    main group molecular entity 19531
                      s-block molecular entity 19314
                        hydrogen molecular entity 19303
                          hydrides 18231
                            organic hydride 17520
                              organic fundamental parent 17520
                                hydrocarbon 16926
                                  cyclic hydrocarbon 15090
                                    monocyclic hydrocarbon 5635
                                      annulene 5449
                                        aromatic annulene 5449
                                          benzene 5449
                                            alkylbenzene 3191
                                              methylbenzene 3051
                                                toluene 2912
                                                  benzyl group 2354
                                                    phenylalanine 2354
                                                      phenylalanine derivative 2346
                                                        tyrosine derivative 373
                                                          L-tyrosine derivative 6
                                                            alpha-methyl-L-dopa 6
                                                              3-methoxy-alpha-methyl-L-tyrosine 0
                                                              alpha-methyl-L-dopa ethyl ester 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.