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Term:ketorolac tromethamine
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Accession:CHEBI:6130 term browser browse the term
Definition:An organoammonium salt resulting from the mixture of equimolar amounts of ketorolac and tromethamine (tris). It has potent non-sedating analgesic and moderate anti-inflammatory effects. It is used in the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
Synonyms:exact_synonym: 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylate
 related_synonym: Acular;   Acuvail;   Dolac;   Formula=C19H24N2O6;   InChI=1S/C15H13NO3.C4H11NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13;5-4(1-6,2-7)3-8/h1-7,11H,8-9H2,(H,18,19);6-8H,1-3,5H2;   InChIKey=BWHLPLXXIDYSNW-UHFFFAOYSA-N;   Lixidol;   SMILES=[NH3+]C(CO)(CO)CO.[O-]C(=O)C1CCn2c1ccc2C(=O)c1ccccc1;   Sprix;   Toradol
 xref: CAS:74103-07-4 "ChemIDplus";   CAS:74103-07-4 "KEGG DRUG";   DrugBank:DB00465;   HMDB:HMDB0014608;   KEGG:D00813;   PMID:19663721 "Europe PMC";   PMID:23016110 "Europe PMC";   PMID:23098098 "Europe PMC";   PMID:23199134 "Europe PMC";   PMID:23302965 "Europe PMC";   PMID:23992042 "Europe PMC";   PMID:8863973 "Europe PMC";   Reaxys:6463165 "Reaxys"

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Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      biological role 19678
        pharmacological role 18794
          analgesic 13056
            ketorolac tromethamine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    main group molecular entity 19614
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18289
                            inorganic hydride 17210
                              pnictogen hydride 17172
                                nitrogen hydride 17008
                                  ammonium 8223
                                    ammonium ion derivative 8218
                                      ammonium compound 5086
                                        organoammonium salt 410
                                          ketorolac tromethamine 0
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