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ONTOLOGY REPORT - ANNOTATIONS


Term:linezolid
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Accession:CHEBI:63607 term browser browse the term
Definition:An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex.
Synonyms:exact_synonym: N-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamide
 related_synonym: Formula=C16H20FN3O4;   InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1;   InChIKey=TYZROVQLWOKYKF-ZDUSSCGKSA-N;   N-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide;   SMILES=CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(N2CCOCC2)c(F)c1
 alt_id: CHEBI:6477
 xref: CAS:165800-03-3 "ChemIDplus";   CAS:165800-03-3 "KEGG COMPOUND";   DrugBank:DB00601;   Drug_Central:1584 "DrugCentral";   KEGG:C08146;   KEGG:D00947;   LINCS:LSM-5750
 xref_mesh: MESH:C098010
 xref: PDBeChem:ZLD;   PMID:21740298 "Europe PMC";   PMID:21815204 "Europe PMC";   PMID:21899392 "Europe PMC";   PMID:22037854 "Europe PMC";   PMID:22064533 "Europe PMC";   PMID:22064542 "Europe PMC";   PMID:22110086 "Europe PMC";   PMID:22134348 "Europe PMC";   PMID:22139199 "Europe PMC";   PMID:22214776 "Europe PMC";   PMID:22230331 "Europe PMC";   PMID:22247123 "Europe PMC";   Patent:US5688792;   Patent:WO957271;   Reaxys:7496939 "Reaxys";   Wikipedia:Linezolid


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linezolid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alas2 5'-aminolevulinate synthase 2 JBrowse link X 23,167,576 23,187,356 RGD:6480464
G Camkv CaM kinase-like vesicle-associated JBrowse link 8 116,715,755 116,730,061 RGD:6480464
G Cdc25b cell division cycle 25B JBrowse link 3 123,731,539 123,741,696 RGD:6480464
G Cfap77 cilia and flagella associated protein 77 JBrowse link 3 7,508,500 7,632,311 RGD:6480464
G Cib2 calcium and integrin binding family member 2 JBrowse link 8 59,123,078 59,139,946 RGD:6480464
G Crym crystallin, mu JBrowse link 1 189,944,895 189,960,069 RGD:6480464
G Csad cysteine sulfinic acid decarboxylase JBrowse link 7 143,781,520 143,810,880 RGD:6480464
G Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) JBrowse link 13 78,857,638 78,885,464 RGD:6480464
G Hba-a2 hemoglobin alpha, adult chain 2 JBrowse link 10 15,589,364 15,590,207 RGD:6480464
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:6480464
G IgG-2a gamma-2a immunoglobulin heavy chain RGD:6480464
G Kifc1 kinesin family member C1 JBrowse link 20 5,509,059 5,526,175 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Mlc1 modulator of VRAC current 1 JBrowse link 7 129,949,984 129,970,314 RGD:6480464
G Phlda3 pleckstrin homology-like domain, family A, member 3 JBrowse link 13 52,588,917 52,592,002 RGD:6480464
G Prcp prolylcarboxypeptidase JBrowse link 1 157,701,089 157,750,177 RGD:6480464
G Prtg protogenin JBrowse link 8 79,489,790 79,593,806 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Stac3 SH3 and cysteine rich domain 3 JBrowse link 7 70,807,427 70,815,271 RGD:6480464
G Trip13 thyroid hormone receptor interactor 13 JBrowse link 1 31,967,980 32,012,923 RGD:6480464
G Zfyve19 zinc finger FYVE-type containing 19 JBrowse link 3 111,013,856 111,021,841 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        antimicrobial agent 17211
          antibacterial agent 12926
            antibacterial drug 3089
              linezolid 21
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                acetamides 11598
                                                  linezolid 21
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