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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:nelarabine
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Accession:CHEBI:63612 term browser browse the term
Definition:A purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N(9)-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G).
Synonyms:exact_synonym: 9-(beta-D-arabinofuranosyl)-6-methoxy-9H-purin-2-amine
 related_synonym: 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine;   Arranon;   Formula=C11H15N5O5;   InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/m1/s1;   InChIKey=IXOXBSCIXZEQEQ-UHTZMRCNSA-N;   SMILES=COc1nc(N)nc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1O;   nelzarabine
 xref: CAS:121032-29-9;   DrugBank:DB01280;   Drug_Central:1892;   KEGG:D05134;   KEGG:D06488;   PMID:18586926;   PMID:19825456;   PMID:20043113;   PMID:20528871;   PMID:20616909;   PMID:20796200;   PMID:21151585;   PMID:21190039;   PMID:21320002;   PMID:21353591;   PMID:21715318;   PMID:21730354;   PMID:21737993;   PMID:22184539;   PMID:63612;   Reaxys:13568768


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Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      application 19420
        pro-agent 8857
          prodrug 8623
            nelarabine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            heteroorganic entity 19175
                              organochalcogen compound 18886
                                organooxygen compound 18809
                                  carbohydrates and carbohydrate derivatives 12196
                                    carbohydrate 12196
                                      carbohydrate derivative 11819
                                        glycosyl compound 10861
                                          glycoside 9213
                                            pentoside 571
                                              arabinoside 569
                                                beta-D-arabinoside 568
                                                  9-beta-D-arabinofuranosylguanine 0
                                                    nelarabine 0
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