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ONTOLOGY REPORT - ANNOTATIONS


Term:succimer
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Accession:CHEBI:63623 term browser browse the term
Definition:A sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning.
Synonyms:exact_synonym: (2R,3S)-2,3-disulfanylsuccinic acid
 related_synonym: (R*,S*)-2,3-Dimercaptobutanedioic acid;   DMSA;   Dimercaptosuccinic acid;   Formula=C4H6O4S2;   InChI=1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+;   InChIKey=ACTRVOBWPAIOHC-XIXRPRMCSA-N;   SMILES=OC(=O)[C@@H](S)[C@@H](S)C(O)=O;   meso-2,3-Dimercaptobernsteinsaeure;   meso-2,3-Dimercaptosuccinic acid;   meso-Dimercaptosuccinic acid;   succimero;   succimerum
 alt_id: CHEBI:9303
 xref: Beilstein:1725150 "ChemIDplus";   CAS:304-55-2 "ChemIDplus";   CAS:304-55-2 "KEGG COMPOUND";   DrugBank:DB00566;   Drug_Central:2486 "DrugCentral";   KEGG:C07598;   KEGG:D00572;   LINCS:LSM-4749
 xref_mesh: MESH:D004113
 xref: PMID:19123743 "Europe PMC";   PMID:21112928 "Europe PMC";   PMID:22234625 "Europe PMC";   Reaxys:1725150 "Reaxys";   Wikipedia:Succimer


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succimer term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G GSR glutathione-disulfide reductase JBrowse link 16 33,633,949 33,680,411 RGD:6480464

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Path 1
Term Annotations click to browse term
  CHEBI ontology 227
    role 227
      chemical role 163
        ligand 6
          chelator 6
            succimer 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 227
    subatomic particle 227
      composite particle 227
        hadron 227
          baryon 227
            nucleon 227
              atomic nucleus 227
                atom 227
                  main group element atom 220
                    main group molecular entity 220
                      s-block molecular entity 174
                        hydrogen molecular entity 172
                          hydrides 114
                            inorganic hydride 76
                              chalcogen hydride 9
                                sulfur hydride 7
                                  hydrogen sulfide 7
                                    thiol group 7
                                      thiol 7
                                        dithiol 2
                                          succimer 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.