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ONTOLOGY REPORT - ANNOTATIONS


Term:tolcapone
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Accession:CHEBI:63630 term browser browse the term
Definition:Benzophenone substituted on one of the phenyl rings at C-3 and C-4 by hydroxy groups and at C-5 by a nitro group, and on the other phenyl ring by a methyl group at C-4. It is an inhibitor of catechol O-methyltransferase.
Synonyms:exact_synonym: (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
 related_synonym: 3,4-dihydroxy-5-nitro-4'-methylbenzophenone;   4'-methyl-3,4-dihydroxy-5-nitrobenzophenone;   Formula=C14H11NO5;   InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3;   InChIKey=MIQPIUSUKVNLNT-UHFFFAOYSA-N;   SMILES=Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O
 alt_id: CHEBI:9617
 xref: DrugBank:DB00323;   Drug_Central:2697 "DrugCentral";   KEGG:D00786;   LINCS:LSM-5282
 xref_mesh: MESH:C066340
 xref: PMID:20381177 "Europe PMC";   PMID:20502133 "Europe PMC";   PMID:21521027 "Europe PMC";   PMID:22136163 "Europe PMC";   Patent:EP237929;   Patent:US5236952;   Reaxys:8151577 "Reaxys";   Wikipedia:Tolcapone


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tolcapone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadac arylacetamide deacetylase JBrowse link 2 150,146,234 150,157,480 RGD:6480464
G Aars alanyl-tRNA synthetase JBrowse link 19 43,193,264 43,215,281 RGD:6480464
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcd2 ATP binding cassette subfamily D member 2 JBrowse link 7 132,294,564 132,343,169 RGD:6480464
G Abhd10 abhydrolase domain containing 10 JBrowse link 11 60,053,719 60,068,142 RGD:6480464
G Acat2 acetyl-CoA acetyltransferase 2 JBrowse link 1 47,972,399 47,992,654 RGD:6480464
G Acox3 acyl-CoA oxidase 3, pristanoyl JBrowse link 14 80,313,202 80,358,115 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:6480464
G Acsl5 acyl-CoA synthetase long-chain family member 5 JBrowse link 1 276,240,703 276,290,012 RGD:6480464
G Acss2 acyl-CoA synthetase short-chain family member 2 JBrowse link 3 151,032,925 151,075,856 RGD:6480464
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Adprhl1 ADP-ribosylhydrolase like 1 JBrowse link 16 81,616,098 81,648,133 RGD:6480464
G Aga aspartylglucosaminidase JBrowse link 16 41,222,225 41,234,169 RGD:6480464
G Aif1 allograft inflammatory factor 1 JBrowse link 20 5,161,350 5,167,176 RGD:6480464
G Ak2 adenylate kinase 2 JBrowse link 5 147,185,474 147,204,050 RGD:6480464
G Akr1c1 aldo-keto reductase family 1, member C1 JBrowse link 17 69,441,253 69,460,334 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Akr1d1 aldo-keto reductase family 1, member D1 JBrowse link 4 65,110,706 65,143,930 RGD:6480464
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 JBrowse link 1 259,641,673 259,674,521 RGD:6480464
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 JBrowse link 5 61,382,351 61,387,359 RGD:6480464
G Aldh1l1 aldehyde dehydrogenase 1 family, member L1 JBrowse link 4 123,516,553 123,564,067 RGD:6480464
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 JBrowse link 10 47,525,486 47,546,535 RGD:6480464
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit JBrowse link X 115,561,329 115,589,792 RGD:6480464
G Amfr autocrine motility factor receptor JBrowse link 19 11,473,538 11,509,500 RGD:6480464
G Apmap adipocyte plasma membrane associated protein JBrowse link 3 146,376,828 146,407,259 RGD:6480464
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:6480464
G Apob apolipoprotein B JBrowse link 6 33,176,826 33,216,381 RGD:6480464
G Apoc2 apolipoprotein C2 JBrowse link 1 80,589,023 80,593,991 RGD:6480464
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6480464
G Apool apolipoprotein O-like JBrowse link X 83,678,269 83,750,550 RGD:6480464
G Arf4 ADP-ribosylation factor 4 JBrowse link 16 2,338,333 2,354,909 RGD:6480464
G Arl1 ADP-ribosylation factor like GTPase 1 JBrowse link 7 29,282,411 29,293,455 RGD:6480464
G Atad1 ATPase family, AAA domain containing 1 JBrowse link 1 251,234,702 251,386,996 RGD:6480464
G Atad3a ATPase family, AAA domain containing 3A JBrowse link 5 173,189,590 173,209,809 RGD:6480464
G Atf5 activating transcription factor 5 JBrowse link 1 100,807,821 100,812,410 RGD:6480464
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 JBrowse link 8 104,190,032 104,221,342 RGD:6480464
G Atp5f1b ATP synthase F1 subunit beta JBrowse link 7 2,504,708 2,511,748 RGD:6480464
G Atp5f1c ATP synthase F1 subunit gamma JBrowse link 17 72,209,321 72,231,562 RGD:6480464
G Atp5f1e ATP synthase F1 subunit epsilon JBrowse link 3 172,563,105 172,566,007 RGD:6480464
G Atp5md ATP synthase membrane subunit DAPIT JBrowse link 1 266,859,961 266,866,753 RGD:6480464
G Atp5me ATP synthase membrane subunit e JBrowse link 14 2,325,308 2,326,436 RGD:6480464
G Atp5mf ATP synthase membrane subunit f JBrowse link 12 11,191,799 11,198,369 RGD:6480464
G Atp5mg ATP synthase membrane subunit g JBrowse link 8 49,220,441 49,227,273 RGD:6480464
G Atp5pf ATP synthase peripheral stalk subunit F6 JBrowse link 11 24,286,806 24,294,419 RGD:6480464
G Atp5po ATP synthase peripheral stalk subunit OSCP JBrowse link 11 32,081,606 32,087,918 RGD:6480464
G Auh AU RNA binding methylglutaconyl-CoA hydratase JBrowse link 17 12,310,178 12,405,224 RGD:6480464
G Bbox1 gamma-butyrobetaine hydroxylase 1 JBrowse link 3 101,425,684 101,474,848 RGD:6480464
G Bcam basal cell adhesion molecule (Lutheran blood group) JBrowse link 1 80,674,463 80,689,122 RGD:6480464
G Bcap29 B-cell receptor-associated protein 29 JBrowse link 6 50,883,758 50,923,743 RGD:6480464
G Bcas2 BCAS2, pre-mRNA processing factor JBrowse link 2 205,662,633 205,670,514 RGD:6480464
G Bmper BMP-binding endothelial regulator JBrowse link 8 24,369,916 24,615,484 RGD:6480464
G Bms1 BMS1 ribosome biogenesis factor JBrowse link 4 150,433,567 150,471,783 RGD:6480464
G Bpgm bisphosphoglycerate mutase JBrowse link 4 61,912,210 61,940,697 RGD:6480464
G Btf3l4 basic transcription factor 3-like 4 JBrowse link 5 128,432,049 128,450,530 RGD:6480464
G C1d C1D nuclear receptor corepressor JBrowse link 14 100,415,645 100,427,878 RGD:6480464
G C1galt1c1 C1GALT1-specific chaperone 1 JBrowse link X 124,921,686 124,926,171 RGD:6480464
G C4b complement C4B (Chido blood group) JBrowse link 20 4,302,344 4,316,752 RGD:6480464
G C5 complement C5 JBrowse link 3
3
14,049,993
14,206,466
14,113,931
14,229,141
RGD:6480464
G C8a complement C8 alpha chain JBrowse link 5 124,348,536 124,403,117 RGD:6480464
G Cbr4 carbonyl reductase 4 JBrowse link 16 31,944,328 31,972,553 RGD:6480464
G Ccnl2 cyclin L2 JBrowse link 5 173,256,301 173,268,279 RGD:6480464
G Cct7 chaperonin containing TCP1 subunit 7 JBrowse link 4 117,235,023 117,252,265 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cfb complement factor B JBrowse link 20 4,536,206 4,542,073 RGD:6480464
G Chchd1 coiled-coil-helix-coiled-coil-helix domain containing 1 JBrowse link 15 4,025,455 4,026,637 RGD:6480464
G Chchd7 coiled-coil-helix-coiled-coil-helix domain containing 7 JBrowse link 5 16,843,253 16,847,809 RGD:6480464
G Chrac1 chromatin accessibility complex subunit 1 JBrowse link 7 114,323,542 114,326,930 RGD:6480464
G Churc1 churchill domain containing 1 JBrowse link 6 99,817,439 99,831,574 RGD:6480464
G Ciao2a cytosolic iron-sulfur assembly component 2A JBrowse link 8 71,786,336 71,798,258 RGD:6480464
G Cidea cell death-inducing DFFA-like effector a JBrowse link 18 63,082,861 63,108,450 RGD:6480464
G Cisd1 CDGSH iron sulfur domain 1 JBrowse link 20 18,493,538 18,506,923 RGD:6480464
G Cltc clathrin heavy chain JBrowse link 10 74,014,560 74,070,578 RGD:6480464
G Cnih4 cornichon family AMPA receptor auxiliary protein 4 JBrowse link 13 99,469,382 99,490,693 RGD:6480464
G Commd6 COMM domain containing 6 JBrowse link 15 86,136,096 86,142,672 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Copg1 COPI coat complex subunit gamma 1 JBrowse link 4 119,815,041 119,840,997 RGD:6480464
G Copg2 COPI coat complex subunit gamma 2 JBrowse link 4 58,064,394 58,195,242 RGD:6480464
G Coq10a coenzyme Q10A JBrowse link 7 2,780,930 2,788,189 RGD:6480464
G Coq3 coenzyme Q3 methyltransferase JBrowse link 5 36,024,673 36,056,664 RGD:6480464
G Cox6c cytochrome c oxidase subunit 6C JBrowse link 7 74,723,177 74,735,650 RGD:6480464
G Cox7a2 cytochrome c oxidase subunit 7A2 JBrowse link 8 87,209,529 87,213,627 RGD:6480464
G Cox7b cytochrome c oxidase subunit 7B JBrowse link X 77,065,427 77,071,676 RGD:6480464
G Cp ceruloplasmin JBrowse link 2 104,744,249 104,803,034 RGD:6480464
G Crem cAMP responsive element modulator JBrowse link 17 57,021,704 57,090,888 RGD:6480464
G Crip2 cysteine-rich protein 2 JBrowse link 6 137,953,545 137,958,491 RGD:6480464
G Cse1l chromosome segregation 1 like JBrowse link 3 163,664,074 163,702,074 RGD:6480464
G Cstb cystatin B JBrowse link 20 10,966,357 10,968,399 RGD:6480464
G Cyc1 cytochrome c-1 JBrowse link 7 117,409,576 117,411,953 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Dap death-associated protein JBrowse link 2 84,275,884 84,328,998 RGD:6480464
G Dctd dCMP deaminase JBrowse link 16 47,177,144 47,222,850 RGD:6480464
G Ddost dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit JBrowse link 5 156,668,924 156,676,036 RGD:6480464
G Ddx18 DEAD-box helicase 18 JBrowse link 13 37,522,558 37,536,066 RGD:6480464
G Dhcr24 24-dehydrocholesterol reductase JBrowse link 5 126,164,708 126,188,926 RGD:6480464
G Dhcr7 7-dehydrocholesterol reductase JBrowse link 1 217,018,916 217,034,890 RGD:6480464
G Dmac1 distal membrane arm assembly complex 1 JBrowse link 5 92,038,050 92,039,146 RGD:6480464
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 JBrowse link 15 59,990,131 60,056,710 RGD:6480464
G Dock11 dedicator of cytokinesis 11 JBrowse link X 122,507,169 122,690,463 RGD:6480464
G Dpm3 dolichyl-phosphate mannosyltransferase subunit 3, regulatory JBrowse link 2 188,583,664 188,584,179 RGD:6480464
G Dpy30 dpy-30 histone methyltransferase complex regulatory subunit JBrowse link 6 22,296,128 22,316,894 RGD:6480464
G Dtymk deoxythymidylate kinase JBrowse link 9 100,921,565 100,930,399 RGD:6480464
G Dynll1 dynein light chain LC8-type 1 JBrowse link 12 47,074,200 47,076,573 RGD:6480464
G Dynlt3 dynein light chain Tctex-type 3 JBrowse link X 14,633,342 14,642,356 RGD:6480464
G Ebp EBP, cholestenol delta-isomerase JBrowse link X 15,049,394 15,055,782 RGD:6480464
G Echs1 enoyl-CoA hydratase, short chain 1 JBrowse link 1 212,570,213 212,579,040 RGD:6480464
G Eloc elongin C JBrowse link 5 2,042,991 2,059,357 RGD:6480464
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:6480464
G Fam162a family with sequence similarity 162, member A JBrowse link 11 67,618,683 67,646,253 RGD:6480464
G Fbll1 fibrillarin-like 1 JBrowse link 10 20,620,957 20,622,600 RGD:6480464
G Fcf1 FCF1 rRNA-processing protein JBrowse link 6 108,796,182 108,808,051 RGD:6480464
G Fga fibrinogen alpha chain JBrowse link 2 181,997,562 182,013,726 RGD:6480464
G Fmc1 formation of mitochondrial complex V assembly factor 1 JBrowse link 4 66,276,835 66,284,868 RGD:6480464
G Gcdh glutaryl-CoA dehydrogenase JBrowse link 19 26,000,497 26,006,970 RGD:6480464
G Glg1 golgi glycoprotein 1 JBrowse link 19 42,983,879 43,088,074 RGD:6480464
G Gmfg glia maturation factor, gamma JBrowse link 1 85,312,473 85,322,860 RGD:6480464
G Gng10 G protein subunit gamma 10 JBrowse link 5 76,182,100 76,189,014 RGD:6480464
G Gng5 G protein subunit gamma 5 JBrowse link 2 252,359,976 252,368,473 RGD:6480464
G Gpc3 glypican 3 JBrowse link X 139,579,268 139,947,093 RGD:6480464
G Gtf2h5 general transcription factor IIH subunit 5 JBrowse link 1 46,978,345 46,985,032 RGD:6480464
G H2az2 H2A.Z variant histone 2 JBrowse link 14 86,687,782 86,706,639 RGD:6480464
G Hbb hemoglobin subunit beta JBrowse link 1 168,971,269 168,972,680 RGD:6480464
G Higd1a HIG1 hypoxia inducible domain family, member 1A JBrowse link 8 130,482,492 130,491,888 RGD:6480464
G Hint3 histidine triad nucleotide binding protein 3 JBrowse link 1 29,413,425 29,423,288 RGD:6480464
G Hist1h4b histone cluster 1 H4 family member B JBrowse link 17 44,522,144 44,526,587 RGD:6480464
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 JBrowse link 10 35,872,619 35,879,911 RGD:6480464
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 JBrowse link 14 7,054,724 7,104,567 RGD:6480464
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 JBrowse link 3 82,924,699 83,048,465 RGD:6480464
G Hsd17b13 hydroxysteroid (17-beta) dehydrogenase 13 JBrowse link 14 7,113,544 7,128,218 RGD:6480464
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 JBrowse link 18 44,810,462 44,897,677 RGD:6480464
G Hsdl2 hydroxysteroid dehydrogenase like 2 JBrowse link 5 76,812,881 76,848,853 RGD:6480464
G Igfbp1 insulin-like growth factor binding protein 1 JBrowse link 14 87,448,716 87,453,783 RGD:6480464
G Ipo7 importin 7 JBrowse link 1 174,655,939 174,696,173 RGD:6480464
G Itm2a integral membrane protein 2A JBrowse link X 78,490,872 78,496,814 RGD:6480464
G Jagn1 jagunal homolog 1 JBrowse link 4 145,399,885 145,404,605 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:6480464
G Lage3 L antigen family, member 3 JBrowse link X 156,355,376 156,356,799 RGD:6480464
G Lbp lipopolysaccharide binding protein JBrowse link 3 154,786,232 154,812,910 RGD:6480464
G Lrrc59 leucine rich repeat containing 59 JBrowse link 10 82,352,390 82,367,047 RGD:6480464
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 4 123,162,086 123,168,330 RGD:6480464
G Lsm5 LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 4 87,016,003 87,019,219 RGD:6480464
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated JBrowse link 7 11,724,932 11,732,020 RGD:6480464
G Magoh mago homolog, exon junction complex subunit JBrowse link 5 127,480,465 127,487,617 RGD:6480464
G Masp1 mannan-binding lectin serine peptidase 1 JBrowse link 11 80,736,424 80,806,278 RGD:6480464
G Matr3 matrin 3 JBrowse link 18 28,351,691 28,390,764 RGD:6480464
G Mcee methylmalonyl CoA epimerase JBrowse link 1 125,229,487 125,252,692 RGD:6480464
G Mcts1 MCTS1, re-initiation and release factor JBrowse link X 124,894,269 124,906,129 RGD:6480464
G Med21 mediator complex subunit 21 JBrowse link 4 180,961,194 180,968,155 RGD:6480464
G Med28 mediator complex subunit 28 JBrowse link 14 70,089,225 70,098,021 RGD:6480464
G Med31 mediator complex subunit 31 JBrowse link 10 58,780,987 58,784,369 RGD:6480464
G Mettl5 methyltransferase like 5 JBrowse link 3 56,101,597 56,113,823 RGD:6480464
G Mfsd5 major facilitator superfamily domain containing 5 JBrowse link 7 143,882,000 143,884,281 RGD:6480464
G Mgst1 microsomal glutathione S-transferase 1 JBrowse link 4 172,119,382 172,134,609 RGD:6480464
G Mia3 MIA SH3 domain ER export factor 3 JBrowse link 13 101,727,434 101,770,127 RGD:6480464
G Mkks McKusick-Kaufman syndrome JBrowse link 3 129,866,542 129,885,213 RGD:6480464
G Mkrn1 makorin ring finger protein 1 JBrowse link 4 67,185,167 67,206,478 RGD:6480464
G Mmadhc metabolism of cobalamin associated D JBrowse link 3 35,783,511 35,801,474 RGD:6480464
G Mrpl1 mitochondrial ribosomal protein L1 JBrowse link 14 14,951,507 15,008,136 RGD:6480464
G Mrpl13 mitochondrial ribosomal protein L13 JBrowse link 7 95,288,400 95,309,997 RGD:6480464
G Mrpl14 mitochondrial ribosomal protein L14 JBrowse link 9 17,687,622 17,698,591 RGD:6480464
G Mrpl18 mitochondrial ribosomal protein L18 JBrowse link 1 48,033,531 48,038,726 RGD:6480464
G Mrpl20 mitochondrial ribosomal protein L20 JBrowse link 5 173,248,245 173,252,775 RGD:6480464
G Mrpl22 mitochondrial ribosomal protein L22 JBrowse link 10 43,601,786 43,612,119 RGD:6480464
G Mrpl23 mitochondrial ribosomal protein L23 JBrowse link 1 215,701,544 215,709,313 RGD:6480464
G Mrpl30 mitochondrial ribosomal protein L30 JBrowse link 9 44,483,809 44,496,116 RGD:6480464
G Mrpl32 mitochondrial ribosomal protein L32 JBrowse link 17 53,102,534 53,105,400 RGD:6480464
G Mrpl36 mitochondrial ribosomal protein L36 JBrowse link 1 31,261,370 31,264,715 RGD:6480464
G Mrpl40 mitochondrial ribosomal protein L40 JBrowse link 11 86,276,616 86,282,452 RGD:6480464
G Mrpl53 mitochondrial ribosomal protein L53 JBrowse link 4 113,942,037 113,942,927 RGD:6480464
G Mrps14 mitochondrial ribosomal protein S14 JBrowse link 13 77,940,454 77,946,201 RGD:6480464
G Mrps18c mitochondrial ribosomal protein S18C JBrowse link 14 10,440,691 10,446,909 RGD:6480464
G Mrps24 mitochondrial ribosomal protein S24 JBrowse link 14 85,947,763 85,951,891 RGD:6480464
G Mrps33 mitochondrial ribosomal protein S33 JBrowse link 4 67,606,971 67,616,056 RGD:6480464
G Mrps36 mitochondrial ribosomal protein S36 JBrowse link 2 30,740,620 30,750,916 RGD:6480464
G Mtap methylthioadenosine phosphorylase JBrowse link 5 107,711,077 107,777,530 RGD:6480464
G Mttp microsomal triglyceride transfer protein JBrowse link 2 243,366,181 243,407,608 RGD:6480464
G Mvk mevalonate kinase JBrowse link 12 47,904,266 47,920,457 RGD:6480464
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit JBrowse link 3 140,106,723 140,125,047 RGD:6480464
G Nat10 N-acetyltransferase 10 JBrowse link 3 93,658,119 93,698,136 RGD:6480464
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 JBrowse link X 123,803,109 123,806,760 RGD:6480464
G Ndufa2 NADH:ubiquinone oxidoreductase subunit A2 JBrowse link 18 29,585,671 29,587,760 RGD:6480464
G Ndufa6 NADH:ubiquinone oxidoreductase subunit A6 JBrowse link 7 123,583,062 123,586,919 RGD:6480464
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 JBrowse link 7 18,683,553 18,696,332 RGD:6480464
G Ndufa9 NADH:ubiquinone oxidoreductase subunit A9 JBrowse link 4 159,371,263 159,399,636 RGD:6480464
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 JBrowse link 5 56,567,109 56,576,676 RGD:6480464
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 JBrowse link 1 162,369,801 162,376,024 RGD:6480464
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 JBrowse link 2 46,372,488 46,476,162 RGD:6480464
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 JBrowse link 5 141,390,577 141,405,507 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nipsnap1 nipsnap homolog 1 JBrowse link 14 85,113,578 85,137,457 RGD:6480464
G Nipsnap2 nipsnap homolog 2 JBrowse link 12 30,527,540 30,566,090 RGD:6480464
G Nme3 NME/NM23 nucleoside diphosphate kinase 3 JBrowse link 10 14,258,232 14,259,365 RGD:6480464
G Nop56 NOP56 ribonucleoprotein JBrowse link 3 122,803,726 122,808,564 RGD:6480464
G Nphp1 nephrocystin 1 JBrowse link 3 120,316,048 120,370,089 RGD:6480464
G Nploc4 NPL4 homolog, ubiquitin recognition factor JBrowse link 10 109,553,518 109,610,087 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Nupr2 nuclear protein 2, transcriptional regulator JBrowse link 12 30,300,936 30,304,041 RGD:6480464
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 JBrowse link 20 28,920,616 28,972,576 RGD:6480464
G Pc pyruvate carboxylase JBrowse link 1 219,759,157 219,859,854 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Pcyt1a phosphate cytidylyltransferase 1, choline, alpha JBrowse link 11 71,547,865 71,592,037 RGD:6480464
G Pdzd11 PDZ domain containing 11 JBrowse link X 70,458,601 70,461,635 RGD:6480464
G Pfdn1 prefoldin subunit 1 JBrowse link 18 29,233,987 29,290,447 RGD:6480464
G Pfdn5 prefoldin subunit 5 JBrowse link 7 143,924,662 143,929,400 RGD:6480464
G Pgm1 phosphoglucomutase 1 JBrowse link 5 118,743,632 118,803,055 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P JBrowse link 11 34,592,128 34,598,253 RGD:6480464
G Pigs phosphatidylinositol glycan anchor biosynthesis, class S JBrowse link 10 65,591,638 65,606,175 RGD:6480464
G Pin4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 JBrowse link X 72,004,413 72,011,667 RGD:6480464
G Plin2 perilipin 2 JBrowse link 5 104,984,413 105,010,863 RGD:6480464
G Plin3 perilipin 3 JBrowse link 9 10,769,739 10,781,659 RGD:6480464
G Pnpla2 patatin-like phospholipase domain containing 2 JBrowse link 1 214,434,638 214,439,720 RGD:6480464
G Polr2g RNA polymerase II subunit G JBrowse link 1 224,991,250 224,998,355 RGD:6480464
G Prpf8 pre-mRNA processing factor 8 JBrowse link 10 63,635,239 63,658,360 RGD:6480464
G Prxl2a peroxiredoxin like 2A JBrowse link 16 17,494,000 17,513,781 RGD:6480464
G Psmc5 proteasome 26S subunit, ATPase 5 JBrowse link 10 94,445,877 94,451,811 RGD:6480464
G Psme2 proteasome activator subunit 2 JBrowse link 15 34,265,552 34,269,851 RGD:6480464
G Ptrh2 peptidyl-tRNA hydrolase 2 JBrowse link 10 74,002,151 74,012,182 RGD:6480464
G Ramac RNA guanine-7 methyltransferase activating subunit JBrowse link 1 143,583,675 143,589,563 RGD:6480464
G Ran RAN, member RAS oncogene family JBrowse link 12 31,319,556 31,324,105 RGD:6480464
G Rap1a RAP1A, member of RAS oncogene family JBrowse link 2 208,193,950 208,215,186 RGD:6480464
G Rbis ribosomal biogenesis factor JBrowse link 2 88,338,018 88,350,785 RGD:6480464
G Rbm8a RNA binding motif protein 8A JBrowse link 2 198,755,261 198,758,028 RGD:6480464
G Rbp1 retinol binding protein 1 JBrowse link 8 106,449,321 106,470,842 RGD:6480464
G Reep6 receptor accessory protein 6 JBrowse link 7 12,240,059 12,246,814 RGD:6480464
G RGD1307100 similar to RIKEN cDNA D630029K19 JBrowse link 2 123,555,742 123,766,675 RGD:6480464
G RGD1309730 similar to RIKEN cDNA B230118H07 JBrowse link 3 91,086,186 91,195,981 RGD:6480464
G RGD1309779 similar to ENSANGP00000021391 JBrowse link 8 68,308,286 68,312,975 RGD:6480464
G RGD1311745 similar to RIKEN cDNA 1110059G10 JBrowse link 8 132,029,618 132,032,971 RGD:6480464
G RGD1563941 similar to hypothetical protein FLJ20010 JBrowse link 8 52,829,196 52,829,610 RGD:6480464
G Rnf7 ring finger protein 7 JBrowse link 8 104,326,719 104,336,098 RGD:6480464
G Rnls renalase, FAD-dependent amine oxidase JBrowse link 1 251,828,285 252,101,963 RGD:6480464
G Romo1 reactive oxygen species modulator 1 JBrowse link 3 151,688,213 151,689,813 RGD:6480464
G Rpa3 replication protein A3 JBrowse link 4 34,279,320 34,282,351 RGD:6480464
G Rpl10a ribosomal protein L10A JBrowse link 20 7,908,309 7,910,867 RGD:6480464
G Rpl15 ribosomal protein L15 JBrowse link 15 8,188,717 8,192,153 RGD:6480464
G Rpl18a ribosomal protein L18A JBrowse link 16 20,293,277 20,295,283 RGD:6480464
G Rpl22 ribosomal protein L22 JBrowse link 5 169,506,150 169,512,875 RGD:6480464
G Rpl22l1 ribosomal protein L22 like 1 JBrowse link 2 115,362,799 115,364,735 RGD:6480464
G Rpl23 ribosomal protein L23 JBrowse link 10 85,721,398 85,725,359 RGD:6480464
G Rpl35a ribosomal protein L35a JBrowse link 11 70,963,223 70,967,146 RGD:6480464
G Rpl36a ribosomal protein L36a JBrowse link X 105,402,867 105,405,580 RGD:6480464
G Rpl41 ribosomal protein L41 JBrowse link 7 2,972,897 2,973,977 RGD:6480464
G Rpl7a ribosomal protein L7a JBrowse link 3 5,458,985 5,461,627 RGD:6480464
G Rpl7l1 ribosomal protein L7-like 1 JBrowse link 9 16,508,477 16,516,502 RGD:6480464
G Rpl9 ribosomal protein L9 JBrowse link 14 44,524,419 44,527,613 RGD:6480464
G Rpp21 ribonuclease P/MRP subunit p21 JBrowse link 20 2,515,541 2,517,471 RGD:6480464
G Rps11 ribosomal protein S11 JBrowse link 1 101,116,641 101,118,749 RGD:6480464
G Rps14 ribosomal protein S14 JBrowse link 18 56,042,532 56,047,316 RGD:6480464
G Rps15a ribosomal protein S15a JBrowse link 1 187,759,865 187,766,734 RGD:6480464
G Rps20 ribosomal protein S20 JBrowse link 5 16,706,052 16,707,214 RGD:6480464
G Rps21-ps1 ribosomal protein S21, pseudogene 1 JBrowse link 5 159,606,647 159,606,990 RGD:6480464
G Rps24 ribosomal protein S24 JBrowse link 16 757,390 762,091 RGD:6480464
G Rps25 ribosomal protein s25 JBrowse link 8 48,727,346 48,729,722 RGD:6480464
G Rps27 ribosomal protein S27 JBrowse link 2 189,572,175 189,573,280 RGD:6480464
G Rps27a ribosomal protein S27a JBrowse link 14 113,966,163 113,968,440 RGD:6480464
G S100a10 S100 calcium binding protein A10 JBrowse link 2 193,892,589 193,901,236 RGD:6480464
G Sc5d sterol-C5-desaturase JBrowse link 8 46,525,406 46,537,014 RGD:6480464
G Scd stearoyl-CoA desaturase JBrowse link 1 264,159,966 264,173,061 RGD:6480464
G Sdha succinate dehydrogenase complex flavoprotein subunit A JBrowse link 1 31,545,631 31,570,601 RGD:6480464
G Sdhb succinate dehydrogenase complex iron sulfur subunit B JBrowse link 5 159,484,378 159,505,063 RGD:6480464
G Sec11c SEC11 homolog C, signal peptidase complex subunit JBrowse link 18 61,490,051 61,506,393 RGD:6480464
G Sec31a SEC31 homolog A, COPII coat complex component JBrowse link 14 10,854,713 10,909,579 RGD:6480464
G Serbp1 Serpine1 mRNA binding protein 1 JBrowse link 4 98,027,563 98,044,717 RGD:6480464
G Sf3b6 splicing factor 3B, subunit 6 JBrowse link 6 29,991,232 29,999,668 RGD:6480464
G Sfxn1 sideroflexin 1 JBrowse link 17 11,046,588 11,082,219 RGD:6480464
G Sik3 SIK family kinase 3 JBrowse link 8 50,310,263 50,520,284 RGD:6480464
G Slc1a5 solute carrier family 1 member 5 JBrowse link 1 78,710,686 78,724,789 RGD:6480464
G Slc25a1 solute carrier family 25 member 1 JBrowse link 11 87,204,248 87,207,265 RGD:6480464
G Slc25a13 solute carrier family 25 member 13 JBrowse link 4 31,134,165 31,757,006 RGD:6480464
G Slc25a4 solute carrier family 25 member 4 JBrowse link 16 49,266,903 49,270,698 RGD:6480464
G Slc25a5 solute carrier family 25 member 5 JBrowse link X 123,404,570 123,407,637 RGD:6480464
G Slc25a6 solute carrier family 25 member 6 JBrowse link 18 70,959,872 70,961,040 RGD:6480464
G Slc39a7 solute carrier family 39 member 7 JBrowse link 20 3,819,416 3,822,788 RGD:6480464
G Smim26 small integral membrane protein 26 JBrowse link 3 138,764,926 138,766,515 RGD:6480464
G Snapin SNAP-associated protein JBrowse link 2 189,878,159 189,880,743 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Snrnp27 small nuclear ribonucleoprotein U4/U6.U5 subunit 27 JBrowse link 4 118,478,075 118,487,633 RGD:6480464
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 JBrowse link 3 137,138,082 137,147,575 RGD:6480464
G Snrpd3 small nuclear ribonucleoprotein D3 polypeptide JBrowse link 20 14,080,562 14,095,644 RGD:6480464
G Snrpe small nuclear ribonucleoprotein polypeptide E JBrowse link 13 50,252,707 50,258,951 RGD:6480464
G Snrpf small nuclear ribonucleoprotein polypeptide F JBrowse link 7 34,478,331 34,485,034 RGD:6480464
G Snrpg small nuclear ribonucleoprotein polypeptide G JBrowse link 4 118,167,267 118,174,846 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Srp14 signal recognition particle 14 JBrowse link 3 110,245,936 110,249,627 RGD:6480464
G Srprb SRP receptor subunit beta JBrowse link 8 111,673,479 111,687,426 RGD:6480464
G Ss18l2 SS18 like 2 JBrowse link 8 130,350,504 130,353,126 RGD:6480464
G Ssr1 signal sequence receptor subunit 1 JBrowse link 17 27,496,369 27,512,781 RGD:6480464
G Stac3 SH3 and cysteine rich domain 3 JBrowse link 7 70,807,427 70,815,271 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Sult2a1 sulfotransferase family 2A member 1 JBrowse link 1 76,558,721 76,614,315 RGD:6480464
G Taf9 TATA-box binding protein associated factor 9 JBrowse link 2 30,664,407 30,668,414 RGD:6480464
G Tbca tubulin folding cofactor A JBrowse link 2 24,449,498 24,505,351 RGD:6480464
G Tceal8 transcription elongation factor A like 8 JBrowse link X 106,713,319 106,715,391 RGD:6480464
G Tfr2 transferrin receptor 2 JBrowse link 12 22,177,382 22,194,330 RGD:6480464
G Timm10 translocase of inner mitochondrial membrane 10 JBrowse link 3 72,226,563 72,230,087 RGD:6480464
G Timm44 translocase of inner mitochondrial membrane 44 JBrowse link 12 2,517,006 2,533,707 RGD:6480464
G Timm8b translocase of inner mitochondrial membrane 8 homolog B JBrowse link 8 55,037,750 55,039,130 RGD:6480464
G Tk2 thymidine kinase 2 JBrowse link 19 917,203 939,236 RGD:6480464
G Tm2d1 TM2 domain containing 1 JBrowse link 5 116,992,405 117,038,882 RGD:6480464
G Tmed10 transmembrane p24 trafficking protein 10 JBrowse link 6 109,169,739 109,205,004 RGD:6480464
G Tmed4 transmembrane p24 trafficking protein 4 JBrowse link 14 86,390,327 86,395,151 RGD:6480464
G Tmed9 transmembrane p24 trafficking protein 9 JBrowse link 17 9,560,735 9,565,249 RGD:6480464
G Tmem126a transmembrane protein 126A JBrowse link 1 156,283,105 156,291,057 RGD:6480464
G Tmem126b transmembrane protein 126B JBrowse link 1 156,262,220 156,274,207 RGD:6480464
G Tmem128 transmembrane protein 128 JBrowse link 14 77,270,794 77,279,979 RGD:6480464
G Tmem203 transmembrane protein 203 JBrowse link 3 2,474,972 2,475,800 RGD:6480464
G Tmem238 transmembrane protein 238 JBrowse link 1 72,623,409 72,629,606 RGD:6480464
G Tmem256 transmembrane protein 256 JBrowse link 10 56,446,022 56,447,138 RGD:6480464
G Tmsb4x thymosin beta 4, X-linked JBrowse link X 28,593,405 28,617,267 RGD:6480464
G Tnfaip8 TNF alpha induced protein 8 JBrowse link 18 44,664,310 44,779,914 RGD:6480464
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:6480464
G Tomm20 translocase of outer mitochondrial membrane 20 JBrowse link 19 59,863,421 59,873,411 RGD:6480464
G Tomm40 translocase of outer mitochondrial membrane 40 JBrowse link 1 80,617,749 80,630,253 RGD:6480464
G Tomm7 translocase of outer mitochondrial membrane 7 JBrowse link 4 7,835,949 7,842,790 RGD:6480464
G Tp53i3 tumor protein p53 inducible protein 3 JBrowse link 13 75,101,759 75,145,967 RGD:6480464
G Trappc2l trafficking protein particle complex 2-like JBrowse link 19 55,423,350 55,428,551 RGD:6480464
G Tspan6 tetraspanin 6 JBrowse link X 104,719,930 104,729,606 RGD:6480464
G Tubb6 tubulin, beta 6 class V JBrowse link 18 63,130,542 63,140,181 RGD:6480464
G Txndc17 thioredoxin domain containing 17 JBrowse link 10 58,776,792 58,779,764 RGD:6480464
G Uchl3-ps1 ubiquitin carboxyl-terminal esterase L3, pseudogene 1 JBrowse link 3 171,092,806 171,134,704 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 JBrowse link 1 190,555,177 190,585,741 RGD:6480464
G Uqcrfs1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 JBrowse link 17 35,677,984 35,682,262 RGD:6480464
G Uvrag UV radiation resistance associated JBrowse link 1 163,844,804 164,101,568 RGD:6480464
G Vdac2 voltage-dependent anion channel 2 JBrowse link 15 2,634,622 2,648,548 RGD:6480464
G Vdac3 voltage-dependent anion channel 3 JBrowse link 16 74,292,466 74,308,910 RGD:6480464
G Vsnl1 visinin-like 1 JBrowse link 6 37,001,360 37,121,969 RGD:6480464
G Washc3 WASH complex subunit 3 JBrowse link 7 28,762,417 28,809,286 RGD:6480464
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:6480464
G Yars1 tyrosyl-tRNA synthetase 1 JBrowse link 5 147,375,350 147,403,578 RGD:6480464
G Yeats4 YEATS domain containing 4 JBrowse link 7 60,287,477 60,294,618 RGD:6480464
G Znrd1 zinc ribbon domain containing 1 JBrowse link 20 2,088,518 2,092,436 RGD:6480464
G Znrf1 zinc and ring finger 1 JBrowse link 19 43,750,205 43,834,962 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            antidyskinesia agent 1129
              antiparkinson drug 846
                tolcapone 335
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      ketone 15780
                                        aromatic ketone 11819
                                          benzophenones 1116
                                            tolcapone 335
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.