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ONTOLOGY REPORT - ANNOTATIONS


Term:vigabatrin
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Accession:CHEBI:63638 term browser browse the term
Definition:A gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase
Synonyms:exact_synonym: 4-aminohex-5-enoic acid
 related_synonym: 4-Amino-5-hexenoic acid;   Formula=C6H11NO2;   GVG;   InChI=1S/C6H11NO2/c1-2-5(7)3-4-6(8)9/h2,5H,1,3-4,7H2,(H,8,9);   InChIKey=PJDFLNIOAUIZSL-UHFFFAOYSA-N;   SMILES=NC(CCC(O)=O)C=C;   gamma-vinyl GABA;   gamma-vinyl-gamma-aminobutyric acid;   vigabatrina;   vigabatrine;   vigabatrinum
 alt_id: CHEBI:9979
 xref: CAS:60643-86-9 "ChemIDplus";   CAS:60643-86-9 "KEGG COMPOUND";   DrugBank:DB01080;   Drug_Central:2819 "DrugCentral";   KEGG:C07500;   KEGG:D00535;   LINCS:LSM-4959
 xref_mesh: MESH:D020888
 xref: PMID:20018576 "Europe PMC";   PMID:20878340 "Europe PMC";   PMID:20926323 "Europe PMC";   PMID:21361740 "Europe PMC";   PMID:22061177 "Europe PMC";   PMID:22061178 "Europe PMC";   PMID:22061182 "Europe PMC";   PMID:22234618 "Europe PMC";   Patent:US3960927;   Wikipedia:Vigabatrin


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vigabatrin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadat aminoadipate aminotransferase JBrowse link 16 32,832,001 32,868,680 RGD:6480464
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:6480464
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:6480464
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:6480464
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480464
G Gnat2 G protein subunit alpha transducin 2 JBrowse link 2 210,880,754 210,890,765 RGD:6480464
G Kyat1 kynurenine aminotransferase 1 JBrowse link 3 8,752,289 8,785,617 RGD:6480464
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6480464
G Pde6g phosphodiesterase 6G JBrowse link 10 109,620,499 109,625,214 RGD:6480464
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19748
    role 19695
      application 19350
        pharmaceutical 19224
          drug 19224
            central nervous system drug 16424
              central nervous system depressant 15997
                anticonvulsant 15139
                  vigabatrin 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19748
    subatomic particle 19744
      composite particle 19744
        hadron 19744
          baryon 19744
            nucleon 19744
              atomic nucleus 19744
                atom 19744
                  main group element atom 19628
                    p-block element atom 19628
                      carbon group element atom 19522
                        carbon atom 19516
                          organic molecular entity 19516
                            organic group 18426
                              organic divalent group 18418
                                organodiyl group 18418
                                  carbonyl group 18306
                                    carbonyl compound 18306
                                      carboxylic acid 17973
                                        amino acid 12448
                                          non-proteinogenic amino acid 1732
                                            gamma-amino acid 129
                                              vigabatrin 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.