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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor
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Accession:CHEBI:63674 term browser browse the term
Definition:An EC 2.6.1.* (transaminase) inhibitor that interferes with the action of 4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19).
Synonyms:related_synonym: 4-aminobutanoate:2-oxoglutarate aminotransferase inhibitor;   4-aminobutanoate:2-oxoglutarate aminotransferase inhibitors;   4-aminobutyrate aminotransferase inhibitor;   4-aminobutyrate aminotransferase inhibitors;   4-aminobutyrate transaminase inhibitor;   4-aminobutyrate transaminase inhibitors;   4-aminobutyrate--2-ketoglutarate aminotransferase inhibitor;   4-aminobutyrate--2-ketoglutarate aminotransferase inhibitors;   4-aminobutyrate--2-oxoglutarate aminotransferase inhibitor;   4-aminobutyrate--2-oxoglutarate aminotransferase inhibitors;   4-aminobutyrate--2-oxoglutarate transaminase (EC 2.6.1.19) inhibitors;   4-aminobutyrate-2-oxoglutarate transaminase inhibitor;   4-aminobutyrate-2-oxoglutarate transaminase inhibitors;   4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitor;   4-aminobutyric acid 2-ketoglutaric acid aminotransferase inhibitors;   4-aminobutyric acid aminotransferase inhibitor;   4-aminobutyric acid aminotransferase inhibitors;   EC 2.6.1.19 inhibitor;   EC 2.6.1.19 inhibitors;   GABA aminotransferase inhibitor;   GABA aminotransferase inhibitors;   GABA transaminase inhibitor;   GABA transaminase inhibitors;   GABA transferase inhibitor;   GABA transferase inhibitors;   GABA--2-oxoglutarate aminotransferase inhibitor;   GABA--2-oxoglutarate aminotransferase inhibitors;   GABA--2-oxoglutarate transaminase inhibitor;   GABA--2-oxoglutarate transaminase inhibitors;   GABA--alpha-ketoglutarate aminotransferase inhibitors;   GABA--alpha-ketoglutarate transaminase inhibitor;   GABA--alpha-ketoglutarate transaminase inhibitors;   GABA--alpha-ketoglutaric acid transaminase inhibitor;   GABA--alpha-ketoglutaric acid transaminase inhibitors;   GABA--alpha-oxoglutarate aminotransferase inhibitor;   GABA--alpha-oxoglutarate aminotransferase inhibitors;   GABA--oxoglutarate aminotransferase inhibitor;   GABA--oxoglutarate aminotransferase inhibitors;   GABA--oxoglutarate transaminase inhibitor;   GABA--oxoglutarate transaminase inhibitors;   GabT inhibitor;   GabT inhibitors;   aminobutyrate aminotransferase inhibitor;   aminobutyrate aminotransferase inhibitors;   aminobutyrate transaminase inhibitor;   aminobutyrate transaminase inhibitors;   beta-alanine aminotransferase inhibitor;   beta-alanine aminotransferase inhibitors;   beta-alanine--oxoglutarate aminotransferase inhibitor;   beta-alanine--oxoglutarate aminotransferase inhibitors;   beta-alanine--oxoglutarate transaminase inhibitor;   beta-alanine--oxoglutarate transaminase inhibitors;   gamma-amino-N-butyrate transaminase inhibitor;   gamma-amino-N-butyrate transaminase inhibitors;   gamma-aminobutyrate aminotransaminase inhibitor;   gamma-aminobutyrate aminotransaminase inhibitors;   gamma-aminobutyrate transaminase inhibitor;   gamma-aminobutyrate transaminase inhibitors;   gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitor;   gamma-aminobutyrate--alpha-ketoglutarate aminotransferase inhibitors;   gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitor;   gamma-aminobutyrate--alpha-ketoglutarate transaminase inhibitors;   gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitor;   gamma-aminobutyrate:alpha-oxoglutarate aminotransferase inhibitors;   gamma-aminobutyric acid aminotransferase inhibitor;   gamma-aminobutyric acid aminotransferase inhibitors;   gamma-aminobutyric acid pyruvate transaminase inhibitor;   gamma-aminobutyric acid pyruvate transaminase inhibitors;   gamma-aminobutyric acid transaminase inhibitor;   gamma-aminobutyric acid transaminase inhibitors;   gamma-aminobutyric acid--2-oxoglutarate transaminase inhibitor;   gamma-aminobutyric acid--2-oxoglutarate transaminase inhibitors;   gamma-aminobutyric acid--alpha-ketoglutarate transaminase inhibitor;   gamma-aminobutyric acid--alpha-ketoglutarate transaminase inhibitors;   gamma-aminobutyric acid--alpha-ketoglutaric acid aminotransferase inhibitor;   gamma-aminobutyric acid--alpha-ketoglutaric acid aminotransferase inhibitors;   gamma-aminobutyric transaminase inhibitor;   gamma-aminobutyric transaminase inhibitors;   glutamate--succinic semialdehyde transaminase inhibitor;   glutamate--succinic semialdehyde transaminase inhibitors
 xref: Wikipedia:4-aminobutyrate_transaminase


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vigabatrin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aadat aminoadipate aminotransferase JBrowse link 16 32,832,001 32,868,680 RGD:6480464
G Abat 4-aminobutyrate aminotransferase JBrowse link 10 7,093,406 7,200,439 RGD:6480464
G Ddc dopa decarboxylase JBrowse link 14 91,905,919 91,996,816 RGD:6480464
G Fmr1 FMRP translational regulator 1 JBrowse link X 154,684,924 154,722,369 RGD:6480464
G Gad1 glutamate decarboxylase 1 JBrowse link 3 56,861,440 56,902,139 RGD:6480464
G Gnat2 G protein subunit alpha transducin 2 JBrowse link 2 210,880,754 210,890,765 RGD:6480464
G Kyat1 kynurenine aminotransferase 1 JBrowse link 3 8,752,289 8,785,617 RGD:6480464
G Mthfr methylenetetrahydrofolate reductase JBrowse link 5 164,844,642 164,864,360 RGD:6480464
G Pde6g phosphodiesterase 6G JBrowse link 10 109,620,499 109,625,214 RGD:6480464
G Reln reelin JBrowse link 4 9,347,533 9,774,257 RGD:6480464

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  CHEBI ontology 19764
    role 19711
      biological role 19710
        biochemical role 19209
          enzyme inhibitor 18091
            EC 2.* (transferase) inhibitor 13517
              EC 2.6.* (nitrogenous group transferase) inhibitor 10
                EC 2.6.1.* (transaminase) inhibitor 10
                  EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor 10
                    (S)-gabaculine + 0
                    rac-gabaculine 0
                    vigabatrin 10
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.