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ONTOLOGY REPORT - ANNOTATIONS


Term:6-hydroxypaclitaxel
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Accession:CHEBI:63859 term browser browse the term
Definition:A taxane diterpenoid that consists of paclitaxel bearing an additional hydroxy substituent at the 6alpha-position.
Synonyms:exact_synonym: (2alpha,5beta,6alpha,7beta,10beta,13alpha)-4,10-diacetoxy-13-{[(2R,3S)-3-(benzoylamino)-2-hydroxy-3-phenylpropanoyl]oxy}-1,6,7-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
 related_synonym: 6-hydroxytaxol;   6alpha-hydroxypaclitaxel;   6alpha-hydroxytaxol;   Formula=C47H51NO15;   InChI=1S/C47H51NO15/c1-24-30(61-43(57)33(51)32(27-16-10-7-11-17-27)48-41(55)28-18-12-8-13-19-28)22-47(58)40(62-42(56)29-20-14-9-15-21-29)36-45(6,38(54)35(60-25(2)49)31(24)44(47,4)5)37(53)34(52)39-46(36,23-59-39)63-26(3)50/h7-21,30,32-37,39-40,51-53,58H,22-23H2,1-6H3,(H,48,55)/t30-,32-,33+,34-,35+,36-,37-,39+,40-,45-,46+,47+/m0/s1;   InChIKey=NDCWHEDPSFRTDA-FJMWQILYSA-N;   SMILES=[H][C@]12[C@H](OC(=O)c3ccccc3)[C@]3(O)C[C@H](OC(=O)[C@H](O)[C@@H](NC(=O)c4ccccc4)c4ccccc4)C(C)=C([C@@H](OC(C)=O)C(=O)[C@]1(C)[C@@H](O)[C@H](O)[C@H]1OC[C@@]21OC(C)=O)C3(C)C
 xref: CAS:153212-75-0 "ChemIDplus"
 xref_mesh: MESH:C086219
 xref: Reaxys:8105272 "Reaxys"


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6-hydroxypaclitaxel term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464

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Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      application 19308
        pharmaceutical 19179
          drug 19179
            antineoplastic agent 16732
              6-hydroxypaclitaxel 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        aromatic carboxylic acid 10745
                                          benzoic acids 10711
                                            benzoate ester 3992
                                              baccatin III 777
                                                paclitaxel 777
                                                  6-hydroxypaclitaxel 1
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