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Accession:CHEBI:64045 term browser browse the term
Definition:A member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist. It is an atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects.
Synonyms:exact_synonym: 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
 related_synonym: 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide;   4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide;   Aminosultopride;   Formula=C17H27N3O4S;   InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21);   InChIKey=NTJOBXMMWNYJFB-UHFFFAOYSA-N;   SMILES=CCN1CCCC1CNC(=O)c1cc(c(N)cc1OC)S(=O)(=O)CC;   amisulprida;   amisulpridum
 xref: CAS:71675-85-9 "ChemIDplus";   DrugBank:DB06288;   Drug_Central:179 "DrugCentral";   HMDB:HMDB0015633;   KEGG:D07310;   LINCS:LSM-1669
 xref_mesh: MESH:D000077582
 xref: PMID:21176108 "Europe PMC";   PMID:21647545 "Europe PMC";   PMID:21663752 "Europe PMC";   PMID:21746752 "Europe PMC";   PMID:21822161 "Europe PMC";   PMID:21845006 "Europe PMC";   PMID:21852060 "Europe PMC";   PMID:21886905 "Europe PMC";   PMID:21888613 "Europe PMC";   PMID:21969105 "Europe PMC";   PMID:22035899 "Europe PMC";   PMID:22059694 "Europe PMC";   PMID:22121864 "Europe PMC";   PMID:22241281 "Europe PMC";   PMID:22250612 "Europe PMC";   Patent:BE872585;   Patent:US4401822;   Reaxys:6876191 "Reaxys";   Wikipedia:Amisulpride

show annotations for term's descendants       view all columns           Sort by:
amisulpride term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Vipr2 vasoactive intestinal peptide receptor 2 JBrowse link 6 143,932,960 144,009,476 RGD:6480464

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      biological role 19596
        xenobiotic 18165
          amisulpride 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        carboacyl group 16930
                                          univalent carboacyl group 16930
                                            carbamoyl group 16610
                                              carboxamide 16610
                                                monocarboxylic acid amide 13174
                                                  arenecarboxamide 6402
                                                    benzamides 6402
                                                      amisulpride 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.