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ONTOLOGY REPORT - ANNOTATIONS


Term:1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine
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Accession:CHEBI:64093 term browser browse the term
Definition:An N-alkylpiperazine that consists of piperazine bearing 2-(benzhydryloxy)ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent and selective inhibitor of dopamine uptake (KD = 5.5 nM in rat striatal membranes).
Synonyms:exact_synonym: 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine
 related_synonym: Formula=C28H34N2O;   GBR 12935;   GBR12935;   InChI=1S/C28H34N2O/c1-4-11-25(12-5-1)13-10-18-29-19-21-30(22-20-29)23-24-31-28(26-14-6-2-7-15-26)27-16-8-3-9-17-27/h1-9,11-12,14-17,28H,10,13,18-24H2;   InChIKey=RAQPOZGWANIDQT-UHFFFAOYSA-N;   SMILES=C(CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)Cc1ccccc1
 xref: CAS:76778-22-8 "ChemIDplus";   LINCS:LSM-3101
 xref_mesh: MESH:C044630
 xref: PMID:1346964 "Europe PMC";   PMID:18596684 "Europe PMC";   PMID:18784647 "Europe PMC";   PMID:19924693 "Europe PMC";   PMID:20576034 "Europe PMC";   PMID:21693154 "Europe PMC";   PMID:21741457 "Europe PMC";   PMID:21990355 "Europe PMC";   PMID:2952763 "Europe PMC";   PMID:3436357 "Europe PMC";   PMID:8007761 "Europe PMC";   PMID:9286626 "Europe PMC";   Reaxys:578614 "Reaxys";   Wikipedia:GBR-12935
 cyclic_relationship: is_conjugate_base_of CHEBI:64092


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1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      application 19339
        refrigerant 17093
          ammonia 16691
            organic amino compound 16690
              tertiary amino compound 8544
                1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    main group molecular entity 19622
                      s-block molecular entity 19388
                        hydrogen molecular entity 19377
                          hydrides 18283
                            inorganic hydride 17204
                              pnictogen hydride 17166
                                nitrogen hydride 17001
                                  azane 16694
                                    ammonia 16691
                                      organic amino compound 16690
                                        tertiary amino compound 8544
                                          N-alkylpiperazine 3030
                                            1-[2-(benzhydryloxy)ethyl]-4-(3-phenylpropyl)piperazine 2
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