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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glutaraldehyde
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Accession:CHEBI:64276 term browser browse the term
Definition:A dialdehyde comprised of pentane with aldehyde functions at C-1 and C-5.
Synonyms:related_synonym: 1,3-Diformylpropane;   1,5-Pentanedial;   1,5-Pentanedione;   Formula=C5H8O2;   Glutardialdehyde;   Glutaric acid dialdehyde;   Glutaric dialdehyde;   InChI=1S/C5H8O2/c6-4-2-1-3-5-7/h4-5H,1-3H2;   InChIKey=SXRSQZLOMIGNAQ-UHFFFAOYSA-N;   PENTANEDIAL;   SMILES=O=CCCCC=O;   glutaral;   glutaralum
 alt_id: CHEBI:45072
 xref: Beilstein:605390;   CAS:111-30-8;   Drug_Central:3267;   HMDB:HMDB0029599;   KEGG:C12518;   KEGG:D01120
 xref_mesh: MESH:D005976
 xref: PDBeChem:PTD;   PMID:10672649;   PMID:11378863;   PMID:22020189;   PMID:22221459;   PMID:22233542;   PMID:22266295;   PMID:22269730;   PMID:22348538;   PMID:22351440;   PMID:24332617;   PMID:7701454;   PMID:9582689;   PPDB:1567;   Reaxys:605390;   Wikipedia:Glutaraldehyde


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glutaraldehyde term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 increases expression ISO Glutaral results in increased expression of ATF4 mRNA CTD PMID:28236482 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Casp8 caspase 8 decreases expression ISO Glutaral results in decreased expression of CASP8 mRNA CTD PMID:28236482 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Glutaral results in increased expression of CCL4 mRNA CTD PMID:20713136 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Cd86 CD86 molecule increases expression ISO Glutaral results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity ISO Glutaral results in decreased activity of G6PD protein CTD PMID:19490936 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Glutaral results in decreased expression of GJA1 protein CTD PMID:19932693 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
ISO Glutaral results in decreased activity of GSR protein
Idarubicin promotes the reaction [Glutaral results in decreased activity of GSR protein]
CTD PMID:19490936 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Il1r2 interleukin 1 receptor type 2 increases expression ISO Glutaral results in increased expression of IL1R2 mRNA CTD PMID:20713136 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il6 interleukin 6 affects expression ISO Glutaral affects the expression of IL6 mRNA CTD PMID:20200221 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Glutaral results in increased expression of PMAIP1 mRNA CTD PMID:20713136 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Tnf tumor necrosis factor affects expression
increases expression
ISO Glutaral affects the expression of TNF mRNA
Glutaral results in increased expression of TNF mRNA
CTD PMID:20200221, PMID:28236482 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Glutaral results in decreased expression of TP53 mRNA CTD PMID:28236482 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        fixative 21
          glutaraldehyde 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        carboacyl group 17346
                                          univalent carboacyl group 17346
                                            formyl group 7845
                                              aldehyde 7845
                                                dialdehyde 117
                                                  glutaraldehyde 12
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